-
公开(公告)号：EP2884324B1
公开(公告)日：2017-12-27
申请号：EP13827299.2
申请日：2013-08-07
IPC分类号： G02B21/18 , G01N21/45 , G01N21/64 , G02B7/04 , G02B21/00 , G02B21/06 , G02B21/14 , G02B21/16
CPC分类号： G02B21/0076 , G01N21/6458 , G01N2021/6441 , G02B21/0056 , G02B21/06 , G02B21/14 , G02B21/16 , G02B21/18
摘要： An observation device is provided as one capable of readily acquiring a fluorescence image and an interference image on a common observation plane in an observation object substantially at the same time. The observation device 1 is a device capable of substantially simultaneously acquiring the fluorescence image and the interference image on the common observation plane in the observation object 90 mounted on slide glass 41, and has an excitation light source 11, a filter 12, a dichroic mirror 13, a lens 14, a dichroic mirror 15, an objective lens 16, a filter 17, a fluorescence imaging unit 18, an interference imaging light source 21, a filter 22, a dichroic mirror 23, a lens 24, a half mirror 25, an objective lens 26, a lens 27, a dichroic mirror 28, an interference imaging unit 29, a position detection light source 31, a light detection unit 32, the slide glass 41, an actuator 42, a reference mirror 43, an actuator 44, a control unit 51, and a display unit 52.
-
公开(公告)号：EP3130913B1
公开(公告)日：2019-02-27
申请号：EP16190479.2
申请日：2008-06-03
发明人： IWAI, Hidenao , YAMAUCHI, Toyohiko
-
公开(公告)号：EP2668465A1
公开(公告)日：2013-12-04
申请号：EP12702385.1
申请日：2012-01-25
CPC分类号： G01B9/04 , G01B9/02032 , G01B9/02047 , G01B9/02064 , G01B9/0207 , G01B9/02084 , G01B9/02091 , G01N21/45 , G02B27/1086 , G02B27/50 , G03H1/0443 , G03H2001/005 , G03H2001/0456 , G03H2222/24
摘要： The present invention relates to a full-field reflection phase microscope. In a preferred embodiment, the invention can combine low-coherence interferometry and off-axis digital holographic microscopy (DHM). The reflection-based DHM provides highly sensitive and a single-shot imaging of cellular dynamics while the use of low coherence source provides a depth-selective measurement. A preferred embodiment of the system uses a diffraction grating in the reference arm to generate an interference image of uniform contrast over the entire field-of-view albeit low-coherence light source. With improved path-length sensitivity, the present invention is suitable for full-field measurement of membrane dynamics in live cells with sub-nanometer-scale sensitivity.
-
公开(公告)号：EP2187198A1
公开(公告)日：2010-05-19
申请号：EP08778292.6
申请日：2008-07-18
发明人： IWAI, Hidenao , YAMAUCHI, Toyohiko
CPC分类号： G01N15/1434 , G01N15/1459 , G01N15/1463 , G01N15/147 , G01N33/4915 , G01N2015/1006 , G01N2015/145 , G01N2015/149 , G01N2015/1493 , G02B21/14 , G06T7/0012 , G06T2207/20056 , G06T2207/30024
摘要： This blood examination apparatus examines cancer cells mixed in an examination object which is flowing blood, and includes: a flow cell through which the examination object is made to flow; an imaging optical system which light output from the examination object in an examination region in the flow cell enters, the imaging optical system forming an image of the light on a first image plane; a first Fourier transformation optical system which optically two-dimensionally Fourier-transforms the image formed on the first image plane by the imaging optical system to form the Fourier-transformed image on a second image plane; a spatial light filter which selectively allows a portion in a certain range around an optical axis of the first Fourier transformation optical system of the image formed on the second image plane by the first Fourier transformation optical system to pass through; and a second Fourier transformation optical system which optically two-dimensionally Fourier-transforms the portion which has passed through the spatial light filter of the image formed on the second image plane by the first Fourier transformation optical system to form the Fourier-transformed image on a third image plane.
摘要翻译： 该血液检查装置检查在流动的血液的检查对象物中混合的癌细胞，并且包括：使检查对象流过的流通池; 在流动池中的检查区域中从检查对象输出的成像光学系统进入成像光学系统，在第一图像平面上形成光的图像; 第一傅立叶变换光学系统，其通过所述成像光学系统光学地二维地傅里叶变换在所述第一图像平面上形成的图像，以在第二图像平面上形成所述傅里叶变换图像; 空间光滤波器，其通过第一傅里叶变换光学系统选择性地允许在第二图像平面上形成的图像的第一傅立叶变换光学系统的光轴周围的一定范围内的部分通过; 以及第二傅里叶变换光学系统，其通过第一傅立叶变换光学系统对通过第二图像平面上形成的图像的空间滤光器的部分进行光学二维傅立叶变换，以形成傅立叶变换图像 第三象机。
-
公开(公告)号：EP2050411A1
公开(公告)日：2009-04-22
申请号：EP07790830.9
申请日：2007-07-17
IPC分类号： A61B18/20
CPC分类号： A61B18/24 , A61B2017/00057 , G02B6/0208 , G02B6/4246
摘要： The light irradiation device 1 is provided with a laser light source 10 for generating laser light, a light source for detection light 20 for generating detection light of a predetermined wavelength, an optical fiber 30 having a FBG 32 for inputting laser light on one end face 30a and emitting the light from the other end face 30b to radiate it to an object 3, inputting detection light on the one end face 30a and also reflecting the light of a predetermined wavelength adjacent to the other end face 30b, a light detector 50 for detecting an intensity of detection light reflected by the FBG 32 and emitted from the one end face 30a, and a signal processing unit 60 for detecting an irradiation state of the laser light to the object 3 based on an intensity of the thus detected detection light. The laser light generated from the laser light source 10 is light other than that of a wavelength reflected by the FBG 32.
摘要翻译： 光照射装置1具有用于产生激光的激光光源10，用于产生预定波长的检测光的检测光用光源20，具有用于在一个端面输入激光的FBG32的光纤30 并从另一端面30b发射光以将其发射到物体3，在一个端面30a上输入检测光并且还反射与另一个端面30b相邻的预定波长的光;光检测器50，用于 检测由FBG32反射并从一个端面30a发射的检测光的强度;以及信号处理单元60，用于基于检测到的检测光的强度来检测激光到被检体3的照射状态。 从激光光源10产生的激光是除FBG32反射的波长以外的光。
-
公开(公告)号：EP2955505B1
公开(公告)日：2020-11-25
申请号：EP14748553.6
申请日：2014-02-05
-
7.发明公开MEASUREMENT INSTRUMENT OF OPTICAL CHARACTERISTICS FOR SAMPLE FLOWING IN PASSAGE 审中-公开EINER PASSAGESTRÖMENDEN探索仪器仪器仪表EIGENSCHAFTENFÜREINE
公开(公告)号：EP3130913A1
公开(公告)日：2017-02-15
申请号：EP16190479.2
申请日：2008-06-03
发明人： IWAI, Hidenao , YAMAUCHI, Toyohiko
CPC分类号： G01B9/02069 , G01B9/0201 , G01B11/06 , G01B2290/35 , G01N21/45
摘要： An optical property measurement apparatus 1 includes a light source unit 10, a first optical coupler 21, a second optical coupler 22, a lens 31, a lens 32, a phase modulation unit 40, a drive unit 41, an optical path length difference adjustment unit 50, a control unit 51, a light receiving unit 60, a synchronization detection unit 70, and a measurement unit 80. The phase modulation unit 40 carries out phase modulation with a frequency f. The synchronization detection unit 70 outputs a first signal having a value corresponding to a magnitude of a component of the frequency f included in an electrical signal output from the light receiving unit 60, and also outputs a second signal having a value corresponding to a magnitude of a component of the frequency 2f included in the electrical signal. The control unit 51 controls the optical path length difference adjusted by the optical path length difference adjustment unit 50 to be a predetermined value based on the first signal or the second signal output from the synchronization detection unit 70.
摘要翻译： 光学特性测量装置1包括光源单元10，第一光耦合器21，第二光耦合器22，透镜31，透镜32，相位调制单元40，驱动单元41，光程长度差调整 单元50，控制单元51，光接收单元60，同步检测单元70和测量单元80.相位调制单元40执行频率f的相位调制。 同步检测单元70输出具有与从光接收单元60输出的电信号中包括的频率f的分量的大小对应的值的第一信号，并且还输出具有对应于 包括在电信号中的频率2f的分量。 控制单元51基于从同步检测单元70输出的第一信号或第二信号，将由光程长度差调整单元50调整的光程长度差控制为预定值。
-
公开(公告)号：EP2187198B1
公开(公告)日：2017-06-28
申请号：EP08778292.6
申请日：2008-07-18
发明人： IWAI, Hidenao , YAMAUCHI, Toyohiko
CPC分类号： G01N15/1434 , G01N15/1459 , G01N15/1463 , G01N15/147 , G01N33/4915 , G01N2015/1006 , G01N2015/145 , G01N2015/149 , G01N2015/1493 , G02B21/14 , G06T7/0012 , G06T2207/20056 , G06T2207/30024
-
9.发明授权MEASUREMENT INSTRUMENT OF OPTICAL CHARACTERISTICS FOR SAMPLE FLOWING IN PASSAGE 有权用于测量光学楼盘在李刚FLOWING PROBE
公开(公告)号：EP2175258B1
公开(公告)日：2017-04-12
申请号：EP08765011.5
申请日：2008-06-03
发明人： IWAI, Hidenao , YAMAUCHI, Toyohiko
CPC分类号： G01B9/02069 , G01B9/0201 , G01B11/06 , G01B2290/35 , G01N21/45
-
公开(公告)号：EP2050411B1
公开(公告)日：2011-03-09
申请号：EP07790830.9
申请日：2007-07-17
IPC分类号： A61B18/20 , A61B18/24 , G01H9/00 , A61N5/067 , A61N5/06 , A61B18/26 , G01L1/24 , G01B11/16 , A61B17/00 , G02B6/02 , A61B17/22
CPC分类号： A61B18/24 , A61B2017/00057 , G02B6/0208 , G02B6/4246
摘要： A light irradiation apparatus (1) is provided with a laser light source (10) for generating laser light; a light source (20) for detection light, for generating detection light having a prescribed wavelength; an optical fiber (30), which permits the laser light to be inputted from one end surface (30a) and to be outputted from the other end surface (30b) to irradiate an object (3), permits the detection light to be inputted from the end surface (30a), and has an FBG (32) in the vicinity of the end surface (30b) for reflecting light having a prescribed wavelength; a light detector (50) for detecting intensity of detection light, which is reflected by the FBG (32) and outputted from the end surface (30a); and a signal processing section (60) for detecting irradiation status of the object (3) with the laser light, based on the detected intensity of the detection light. The laser light generated from the laser light source (10) has a wavelength other than that reflected by the FBG (32).
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.012 秒)
