-
1.发明公开BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE 审中-公开具有锁定效应蛋白激酶双环杂芳基衍生物
公开(公告)号：EP2528920A2
公开(公告)日：2012-12-05
申请号：EP11737311.8
申请日：2011-01-28
发明人： JUNG, Seung Hyun , JUNG, Young Hee , CHOI, Wha Il , SON, Jung Beom , JEON, Eun Ju , YANG, In Ho , SONG, Tae Hun , LEE, Mi Kyoung , KO, Myoung Sil , AHN, Young Gil , KIM, Maeng Sup , HAM, Young Jin , SIM, Tae Bo , CHOI, Hwan Geun , HAH, Jung Mi , PARK, Dong-sik , KIM, Hwan
IPC分类号： C07D487/04 , C07D495/04 , A61K31/519 , A61P43/00
CPC分类号： C07D495/04
摘要： The present invention relates to a novel bicyclic heteroaryl derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof, and a solvate thereof having an improved inhibitory activity for protein kinases, and a pharmaceutical composition for preventing or treating an abnormal cell growth disorder comprising same as an active ingredient.
-
2.发明公开
公开(公告)号：EP1765822A1
公开(公告)日：2007-03-28
申请号：EP05753525.4
申请日：2005-06-14
发明人： YOO, Kyung Ho, Gunyoung Apt. 104-1501 , KIM, D. J., Taereung Hyundai Hometwn Sweet 104-306 , KANG, Yong Koo, Gunyoung 3-cha Apt. , LEE, Kyung Seok , LEE, Gwan Sun , KIM, Maeng Sup , KANG, Jae Hoon
IPC分类号： C07D477/20
CPC分类号： C07D477/20
摘要： The present invention relates to a novel 1β-methylcarbapenem derivative, a process for the preparation thereof and a pharmaceutical composition comprising the 1β-methylcarbapenem derivative or a pharmaceutically acceptable salt thereof as an active antibacterial ingredient.
摘要翻译： 本发明涉及一种新的1β-甲基碳代青霉烯衍生物，其制备方法和含有1β-甲基碳代青霉烯衍生物或其药学上可接受的盐作为活性抗菌成分的药物组合物。
-
3.发明授权THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROTEIN KINASES 有权噻吩并[3,2-d]嘧啶衍生物对蛋白激酶具有抑制活性
公开(公告)号：EP2528925B1
公开(公告)日：2017-07-05
申请号：EP11737323.3
申请日：2011-01-31
申请人： Hanmi Science Co., Ltd. , Korea Institute of Science and Technology , Catholic University Industry Academic Cooperation Foundation
发明人： SON, Jung Beom , JUNG, Seung Hyun , CHOI, Wha Il , JUNG, Young Hee , CHOI, Jae Yul , SONG, Ji Yeon , LEE, Kyu Hang , LEE, Jae Chul , KIM, Eun Young , AHN, Young Gil , KIM, Maeng Sup , CHOI, Hwan Geun , SIM, Tae Bo , HAM, Young Jin , PARK, Dong-sik , KIM, Hwan , KIM, Dong-Wook
IPC分类号： C07D495/04 , C07D495/14 , C07D409/14 , A61P35/00
CPC分类号： C07D495/04
-
4.发明公开THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROTEIN KINASES 有权带有锁定对蛋白激酶噻吩并[3,2-D]嘧啶衍生物
公开(公告)号：EP2528925A2
公开(公告)日：2012-12-05
申请号：EP11737323.3
申请日：2011-01-31
申请人： Hanmi Science Co., Ltd. , Korea Institute of Science and Technology , Catholic University Industry Academic Cooperation
发明人： SON, Jung Beom , JUNG, Seung Hyun , CHOI, Wha Il , JUNG, Young Hee , CHOI, Jae Yul , SONG, Ji Yeon , LEE, Kyu Hang , LEE, Jae Chul , KIM, Eun Young , AHN, Young Gil , KIM, Maeng Sup , CHOI, Hwan Geun , SIM, Tae Bo , HAM, Young Jin , PARK, Dong-sik , KIM, Hwan , KIM, Dong-Wook
IPC分类号： C07D495/04 , C07D495/14 , C07D409/14 , A61P35/00
CPC分类号： C07D495/04
摘要： The present invention relates to a thieno[3,2-d]pyrimidine derivative of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, which has an excellent inhibitory activity on protein kinases, and a pharmaceutical composition comprising the same is effective in preventing or treating abnormal cell growth diseases.
-
5.发明公开STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF 审中-公开作为β-淀粉样蛋白纤维形成抑制剂的STYRYLBENZOFURAN衍生物及其制备方法
公开(公告)号：EP2291364A2
公开(公告)日：2011-03-09
申请号：EP09762685.7
申请日：2009-06-12
发明人： KIM, Dong Jin , YOO, Kyung Ho , BYUN, Ji Hun , KIM, YoungSoo , KIM, Hye Yun , LEE, Gwan Sun , KIM, Maeng Sup , AHN, Young Gil , LEE, Ji Hoon , LEE, Myoung-Hwan , HWANG, Hana , RYU, Jiyeon
IPC分类号： C07D307/78 , A61K31/343
CPC分类号： C07D307/81 , C07D307/80
摘要： The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.
摘要翻译： 本发明涉及有效抑制脑中β-淀粉样原纤维形成以用于预防或治疗退行性脑疾病的新型化合物，其制备方法，以及包含其作为活性成分的药物组合物。
-
6.发明公开QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF 有权喹唑啉衍生物ALS抑制剂MULTIPLEX AND METHOD FOR THEIR
公开(公告)号：EP1951686A1
公开(公告)日：2008-08-06
申请号：EP06812505.3
申请日：2006-11-08
发明人： AHN, Young-Gil , KIM, Jong Woo , BANG, Keuk Chan , PARK, Bum Woo , KIM, Se Young , LEE, Kyungik , LEE, Kyuhang , KO, Myoung-Sil , KIM, Han Kyong , KIM, Young Hoon , KIM, Maeng Sup , LEE, Gwan Sun
IPC分类号： C07D239/94 , A61K31/517 , A61P35/00 , A61P29/00
CPC分类号： C07D239/94
摘要： The present invention relates to a novel quinazoline derivative and a pharmaceutically acceptable salt thereof as a multiplex inhibitor, a method for the preparation thereof, and a pharmaceutical composition and a therapeutic composition comprising same as an active ingredient. The inventive quinazoline derivative as a multiplex inhibitor can selectively and effectively inhibit diseases caused by the overactivity of a tyrosine kinase.
-
7.发明授权QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF 有权喹唑啉衍生物ALS抑制剂MULTIPLEX AND METHOD FOR THEIR
公开(公告)号：EP1951686B1
公开(公告)日：2013-04-03
申请号：EP06812505.3
申请日：2006-11-08
发明人： AHN, Young-Gil , KIM, Jong Woo , BANG, Keuk Chan , PARK, Bum Woo , KIM, Se Young , LEE, Kyungik , LEE, Kyuhang , KO, Myoung-Sil , KIM, Han Kyong , KIM, Young Hoon , KIM, Maeng Sup , LEE, Gwan Sun
IPC分类号： C07D239/94 , A61K31/517 , A61P35/00 , A61P29/00
CPC分类号： C07D239/94
-
公开(公告)号：EP2167492A2
公开(公告)日：2010-03-31
申请号：EP08766124.5
申请日：2008-06-05
发明人： LEE, Kwang-Ok , CHA, Mi Young , KIM, Mi Ra , JUNG, Young Hee , LEE, Chang Gon , KIM, Se Young , BANG, Keukchan , PARK, Bum Woo , CHOI, Bo Im , CHAE, Yun Jung , KO, Mi Young , KIM, Han Kyong , AHN, Young-Gil , KIM, Maeng Sup , LEE, Gwan Sun
IPC分类号： C07D403/12
CPC分类号： C07D403/12 , C07D401/12 , C07D401/14 , C07D403/14
摘要： The present invention provides a novel amide derivative and a pharmaceutically acceptable salt thereof which selectively and effectively inhibits the growth of cancer cells induced by the overexpression of an epidermal growth factor receptor and also prevents the development of drug resistance caused by the mutation of EGFR tyrosine kinase, and a pharmaceutical composition comprising same as an active ingredient.
-
9.发明公开NOVEL P-GLYCOPROTEIN INHIBITOR, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME 审中-公开新的P-GLYCOPROTEININHIBITOR，对于其方法和药物组合物包含此
公开(公告)号：EP1711490A1
公开(公告)日：2006-10-18
申请号：EP04774781.1
申请日：2004-10-07
发明人： CHA, Mi Young, Cheongsolmaeul Halla Apt. , BANG, Keuk Chan, Mansujugong Apt. , AHN, Young Gil, Sangrokmaeul Life Apt. , KIM, Maeng Sup , LEE, Gwan Sun
IPC分类号： C07D405/12
CPC分类号： C07D405/12
摘要： A p-glycoprotein inhibitor of Formula 1 is capable of effectively preventing the development of multi-drug resistance directed to an anticancer agent in cancer cells, and greatly enhances the bioavailability of the drug, such as paclitaxel, which is not readily absorbed when orally administered.
-
10.发明公开
公开(公告)号：EP1678162A1
公开(公告)日：2006-07-12
申请号：EP04774778.7
申请日：2004-10-06
发明人： BANG, Keuk Chan , CHA, Mi Young , AHN, Young Gil , HAM, Young Jin , KIM, Maeng Sup , LEE, Gwan Sun
IPC分类号： C07D401/14
CPC分类号： C04B35/632 , C07D257/04 , C07D401/12 , C07D405/12 , C07D409/12
摘要： The bioavailability of an anticancer agent is enhanced when the anticancer agent is administered together with a pharmaceutical composition comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof.
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.027 秒)
