公开(公告)号：EP4442871A1

公开(公告)日：2024-10-09

申请号：EP22901406.3

申请日：2022-12-01

申请人： HiPep Laboratories

发明人： NOKIHARA, Kiyoshi ,  SASAKI, Toru ,  KASAMA, Takeshi

IPC分类号： C40B40/10 ,  C07K5/12 ,  C07K7/54 ,  C07K7/64 ,  C07K17/00 ,  G01N33/545

CPC分类号： C07K5/12 ,  C07K7/54 ,  C07K7/64 ,  C07K17/00 ,  G01N33/545 ,  C40B40/10

摘要： Disclosed is a peptide-immobilized bead library from which peptides are more likely to be obtained as candidates of useful substances such as pharmaceuticals, and with which the amino acid sequence bound to a target substance can be more easily analyzed, compared to known OPOB libraries. The peptide-immobilized bead library has a structure of General Formula [I].

In General Formula [I], X is an amino acid residue; n is an integer of 4 to 8; Y is a cyclization structure; A is a spacer structure; B is a specific cleavage site-containing structure; and the 4 to 8 amino acid residues of X are each independently randomly selected.