公开(公告)号：EP1778283A2

公开(公告)日：2007-05-02

申请号：EP05851200.5

申请日：2005-06-30

申请人： ID Biomedical Corporation of Quebec

发明人： BURT, David, S. ,  REDDISH, Mark, A. ,  HU, Mary, ChaoHong ,  LOWELL, George, H. ,  JONES, David, Hugh

IPC分类号： A61K39/215 ,  C07K14/165

CPC分类号： A61K39/215 ,  A61K39/12 ,  A61K2039/543 ,  A61K2039/55511 ,  A61K2039/55516 ,  A61K2039/55572 ,  A61K2039/57 ,  C07K14/005 ,  C12N2770/20022 ,  C12N2770/20034

摘要： The present disclosure relates to compositions and methods for treating or preventing coronavirus infections. For example, compositions are provided that comprise a coronavirus S protein or N protein, fragment, or variant thereof, capable of eliciting a protective humoral and/or cell-mediated immune response, which compositions are useful for treating or preventing infection by coronavirus, such as the causative agent of SARS. Also, coronavirus S protein and N protein immunogen compositions are provided that include an adjuvant, such as Proteosome or Protollin, which may be used for treating or preventing infection caused by a coronavirus, such as a SARS coronavirus.