公开(公告)号：EP2430428A4

公开(公告)日：2017-11-15

申请号：EP11755662

申请日：2011-03-15

Applicant: IND TECH RES INST

Inventor： CHIOU CHUNG-FAN ,  PU YING-CHIH ,  PAN CHAO-CHI ,  SHIH CHIH-TSUNG ,  LI MING-CHIA ,  KUO CHEIN-SHIU ,  CHIEN HUNG-CHI ,  CHU CHANG-SHENG

IPC: G01N21/64 ,  C12Q1/68

CPC classification number: C12Q1/6869 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6454 ,  G01N21/648 ,  G01N21/7703 ,  G01N2021/6439 ,  G01N2201/08 ,  G01N2201/12 ,  C12Q2563/155 ,  C12Q2561/113

Abstract: Embodiments encompass a single-molecule detection system and methods of using the detection system to detect an object. Further, embodiments encompass a detection system comprising a movable light coupler, a waveguide, and a light detector. Embodiments further encompass methods of single-molecule detection, including methods of single-molecule nucleic acid sequencing.

公开(公告)号：EP2580576A4

公开(公告)日：2015-08-12

申请号：EP11791952

申请日：2011-06-10

Applicant: IND TECH RES INST

Inventor： CHIOU CHUNG-FAN ,  TSAI RUNG-YWAN ,  LI YU-TANG ,  SHIH CHIH-TSUNG ,  LI MING-CHIA ,  CHU CHANG-SHENG ,  CHUNG SHUANG-CHAO ,  CHEN JUNG-PO ,  PU YING-CHIH

IPC: G01N21/63 ,  B82B1/00 ,  B82Y15/00 ,  C12Q1/68 ,  G01N21/64 ,  G01N21/77 ,  G01N33/543

CPC classification number: G01N21/6486 ,  B82Y15/00 ,  G01N21/645 ,  G01N21/648 ,  G01N21/7703 ,  G01N33/54373 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/088 ,  Y10S977/954 ,  Y10S977/957 ,  Y10S977/958 ,  Y10T436/143333 ,  Y10T436/145555

Abstract: An apparatus for detecting an object capable of emitting light. The apparatus includes a light source and a waveguide. The waveguide includes a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further includes a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell.

Abstract translation: 一种用于检测能够发光的物体的装置。 该装置包括光源和波导。 波导包括芯层和第一覆层。 在至少第一包层中形成至少一个纳米线。 该装置还包括光检测器。 光检测器可以检测从包含在至少一个纳米线中的单个分子物体发射的光。

公开(公告)号：EP2300801A4

公开(公告)日：2011-09-14

申请号：EP10750363

申请日：2010-03-10

Applicant: IND TECH RES INST

Inventor： CHEN HUNG-CHUN ,  LI MING-CHIA ,  CHU CHANG-SHENG ,  LI YU-TANG ,  CHIOU CHUNG-FAN

IPC: G01N21/01 ,  C12Q1/68 ,  G01N15/14 ,  G01N21/27

CPC classification number: G01N21/6428 ,  C12Q1/6869 ,  G01N15/1459 ,  G01N21/645 ,  G01N2015/1477 ,  G01N2015/149 ,  G01N2021/6441 ,  C12Q2565/607 ,  C12Q2563/107 ,  C12Q2537/157

Abstract: An apparatus for detecting an object capable of emitting light. The apparatus comprises a light detector comprising at least two optical sensors capable of determining the intensity of the light; and a computer processing output signal generated by the optical sensors and comparing a processing result with a know result corresponding to a know type to determine whether the object belongs to the known type. A method for detecting an object capable of emitting light is also provided.