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    PROCEDE ET DISPOSITIF DE SEPARATION AVEC DES ZONES CHROMATOGRAPHIQUES A LONGUEUR VARIABLE
    1.
    发明公开
    PROCEDE ET DISPOSITIF DE SEPARATION AVEC DES ZONES CHROMATOGRAPHIQUES A LONGUEUR VARIABLE 有权
    可变长度的色谱区分离工艺

    公开(公告)号：EP1128881A1

    公开(公告)日：2001-09-05

    申请号：EP99950884.9

    申请日：1999-10-29

    申请人： INSTITUT FRANCAIS DU PETROLE ,  Novasep

    发明人： BAILLY, Michel ,  ADAM, Philippe ,  LUDEMANN-HOMBOURGER, Olivier ,  NICOUD, Roger, Marc

    IPC分类号： B01D15/02

    CPC分类号： B01D15/1828 ,  B01D2215/023

    摘要： The invention concerns a method for separating at least a constituent of a mixture in a set of looping chromatographic columns, the loop comprising at least a point for injecting a load, a point for drawing off the raffinate, a point for injecting an eluting agent and a point for drawing of the extract. The method consists in: determining between an injection point and a drawing off point or vice-versa a chromatographic zone and at the end of a specific time interval, the whole set of injection points and drawing off points are offset by the same number of columns or column sections and advantageously from one column or one column section in a specific direction defined with respect to that of the flow of the main fluid circulating through the loop. During said time interval, the offsetting of the different injection and drawing off points of at least one column or column section is carried out at different times such that the length of the zones defined by the different points varies. The invention is useful in particular for separating stereoisomers for pharmaceutical purposes.

    CHROMATOGRAPHIC PROCESS FOR THE PRODUCTION OF HIGHLY PURIFIED POLYUNSATURATED FATTY ACIDS
    3.
    发明公开
    CHROMATOGRAPHIC PROCESS FOR THE PRODUCTION OF HIGHLY PURIFIED POLYUNSATURATED FATTY ACIDS 审中-公开
    色谱过程生产高纯度，多不饱和脂肪酸

    公开(公告)号：EP2994523A1

    公开(公告)日：2016-03-16

    申请号：EP14720547.0

    申请日：2014-04-23

    申请人： Groupe Novasep

    发明人： VALERY, Eric ,  ADAM, Philippe ,  BLEHAUT, Jean

    IPC分类号： C11C1/08 ,  B01D15/18

    CPC分类号： B01D15/185 ,  B01D15/1892 ,  C11C1/08

    摘要： The invention relates to a process for recovering a first polyunsaturated fatty acid from a feed mixture, wherein the feed mixture comprises at least a second fatty acid in addition to the first polyunsaturated fatty acid, the process comprising: - performing a main step of chromatographic separation using an aqueous organic eluent and thereby collecting a first stream of eluent enriched in the first polyunsaturated fatty acid and a second stream of eluent enriched in the second fatty acid; - subjecting the second stream of eluent to a concentration step so as to obtain a stream of concentrated fatty acids on the one hand and a depleted second stream of eluent on the other hand, wherein the water-to-organic ratio of the depleted second stream of eluent is lower than the water-to-organic ratio of the second stream of eluent; recycling at least part of the depleted second stream of eluent to use it in the main step of chromatographic separation.

    PROCEDE DE SEPARATION AVEC DES ZONES CHROMATOGRAPHIQUES A LONGUEUR VARIABLE
    5.
    发明授权
    PROCEDE DE SEPARATION AVEC DES ZONES CHROMATOGRAPHIQUES A LONGUEUR VARIABLE 有权
    可变长度的色谱区分离工艺

    公开(公告)号：EP1128881B1

    公开(公告)日：2005-06-08

    申请号：EP99950884.9

    申请日：1999-10-29

    申请人： Institut Français du Pétrole ,  Novasep

    发明人： BAILLY, Michel ,  ADAM, Philippe ,  LUDEMANN-HOMBOURGER, Olivier ,  NICOUD, Roger, Marc

    IPC分类号： B01D15/02

    CPC分类号： B01D15/1828 ,  B01D2215/023

    摘要： The invention concerns a method for separating at least a constituent of a mixture in a set of looping chromatographic columns, the loop comprising at least a point for injecting a load, a point for drawing off the raffinate, a point for injecting an eluting agent and a point for drawing of the extract. The method consists in: determining between an injection point and a drawing off point or vice-versa a chromatographic zone and at the end of a specific time interval, the whole set of injection points and drawing off points are offset by the same number of columns or column sections and advantageously from one column or one column section in a specific direction defined with respect to that of the flow of the main fluid circulating through the loop. During said time interval, the offsetting of the different injection and drawing off points of at least one column or column section is carried out at different times such that the length of the zones defined by the different points varies. The invention is useful in particular for separating stereoisomers for pharmaceutical purposes.