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公开(公告)号：EP3230461A1
公开(公告)日：2017-10-18
申请号：EP15807648.9
申请日：2015-12-07
发明人： CHARNEAU, Pierre , DESPRES, Philippe , DE WISPELAERE, Melissanne , SOUQUE, Philippe , FRENKIEL, Marie-Pascale
CPC分类号： A61K39/12 , A61K9/19 , A61K47/26 , A61K2039/5256 , A61K2039/5258 , A61K2039/54 , A61K2039/552 , A61K2039/575 , C07K14/005 , C07K14/1825 , C07K2319/40 , C12N7/00 , C12N15/86 , C12N2740/15043 , C12N2740/16043 , C12N2770/24122 , C12N2770/24123 , C12N2770/24134 , C12N2770/24171 , Y02A50/39
摘要： The present invention relates to a lentiviral vector-based Japanese encephalitis (JE) immunogenic composition. The present invention is directed to a recombinant lentiviral vector expressing the precursor of membrane (prM) and the envelope (E) protein, in particular glycoprotein of a Japanese encephalitis virus (JEV) or immunogenic fragments thereof. The present invention also provides cells expressing the lentiviral vector, uses and methods to prevent a JEV infection in a mammalian host, especially in a human or an animal host.
摘要翻译： 基于慢病毒载体的日本脑炎（JE）免疫原性组合物本发明涉及基于慢病毒载体的日本脑炎（JE）免疫原性组合物。 本发明涉及表达膜（prM）前体和包膜（E）蛋白，特别是日本脑炎病毒（JEV）的糖蛋白或其免疫原性片段的重组慢病毒载体。 本发明还提供了表达慢病毒载体的细胞，用于和预防哺乳动物宿主，尤其是人或动物宿主，特别是猪或小猪，优选家猪或家养仔猪JEV感染的方法。
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公开(公告)号：EP4214223A1
公开(公告)日：2023-07-26
申请号：EP21790380.6
申请日：2021-09-21
申请人： Theravectys , INSTITUT PASTEUR
发明人： CHARNEAU, Pierre , ANNA, François , NEVO, Fabien , NOIRAT, Amandine , JACOB, Yves , SOUQUE, Philippe
IPC分类号： C07K14/165 , G01N33/50
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3.发明授权NOVEL ISOLATED AND PURIFIED STRAINS OF CHIKUNGUNYA VIRUS AND POLYNUCLEOTIDES AND POLYPEPTIDES SEQUENCES, DIAGNOSTIC AND IMMUNOGENICAL USES THEREOF 有权新的和孤立的AUFGEREIGNIGTECHIKUNGUNYAVIRENSTÄMME，多核苷酸和多肽，其诊断和用途免疫原性
公开(公告)号：EP2001900B1
公开(公告)日：2015-04-29
申请号：EP07734896.9
申请日：2007-03-15
申请人： INSTITUT PASTEUR
发明人： DESPRES, Philippe , BREHIN, Anne-Claire , MARECHAL, Valérie , CHARNEAU, Pierre , SOUQUE, Philippe
IPC分类号： C07K14/18
CPC分类号： G01N33/56983 , A61K38/00 , A61K39/00 , C07K14/005 , C07K16/1081 , C12N7/00 , C12N2770/36121 , C12N2770/36122 , C12N2770/36131 , G01N2333/181 , G01N2800/32 , Y02A50/383 , Y02A50/51
摘要： The present invention concerns wild-strains of Chikungunya virus isolated from patients exhibiting severe forms of infection and stemming from a human arbovirosis epidemy. The present invention also concerns polypeptide sequences and fragment thereof derived from their genome, the polynucleotide encoding same and their use as diagnostic products, as vaccine and/or as immunogenic compositions.
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4.发明公开NOVEL ISOLATED AND PURIFIED STRAINS OF CHIKUNGUNYA VIRUS AND POLYNUCLEOTIDES AND POLYPEPTIDES SEQUENCES, DIAGNOSTIC AND IMMUNOGENICAL USES THEREOF 有权新的和孤立的AUFGEREIGNIGTECHIKUNGUNYAVIRENSTÄMME，多核苷酸和多肽，其诊断和用途免疫原性
公开(公告)号：EP2001900A2
公开(公告)日：2008-12-17
申请号：EP07734896.9
申请日：2007-03-15
申请人： INSTITUT PASTEUR
发明人： DESPRES, Philippe , BREHIN, Anne-Claire , MARECHAL, Valérie , CHARNEAU, Pierre , SOUQUE, Philippe
IPC分类号： C07K14/18
CPC分类号： G01N33/56983 , A61K38/00 , A61K39/00 , C07K14/005 , C07K16/1081 , C12N7/00 , C12N2770/36121 , C12N2770/36122 , C12N2770/36131 , G01N2333/181 , G01N2800/32 , Y02A50/383 , Y02A50/51
摘要： The present invention concerns wild-strains of Chikungunya virus isolated from patients exhibiting severe forms of infection and stemming from a human arbovirosis epidemy. The present invention also concerns polypeptide sequences and fragment thereof derived from their genome, the polynucleotide encoding same and their use as diagnostic products, as vaccine and/or as immunogenic compositions.
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