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    N-Benzoyl urea compounds, antitumorous compositions containing them, and process for their preparation
    5.
    发明公开
    N-Benzoyl urea compounds, antitumorous compositions containing them, and process for their preparation 失效
    含有它们的制备抗肿瘤这些组合物和方法的N-苯甲酰脲化合物。

    公开(公告)号：EP0226104A2

    公开(公告)日：1987-06-24

    申请号：EP86116595.9

    申请日：1986-11-28

    申请人： ISHIHARA SANGYO KAISHA, LTD.

    发明人： Takahiro, Haga ,  Nobutoshi, Yamada ,  Hideo, Sugi ,  Toru, Koyanagi ,  Hiroshi, Okada

    IPC分类号： C07D239/34 ,  C07D213/64 ,  C07D237/14 ,  A61K31/495 ,  A61K31/44

    CPC分类号： C07D213/643 ,  C07D237/14 ,  C07D239/34

    摘要： An N-benzoyl urea compound having the formula:
    wherein X is a hydrogen atom, a halogen atom or a nitro group, n is an integer of from 1 to 3, and Q is
    wherein Y, is an unsubstituted or substituted alkyl group, or an alkoxy or alkoxycarbonyl group with its alkyl moiety unsubstituted or substituted, Y 2 is a hydrogen atom, a halogen atom, a nitro group, an unsubstituted or substituted alkyl group, or an alkoxy or alkoxycarbonyl group with its alkyl moiety unsubstituted or substituted, Z is a hydrogen atom, a halogen atom, a trifluoromethyl group or a nitro group, and each of A and B is =CH- or a nitrogen atom, provided that one of A and B is =CH- and the other is a nitrogen atom, with the provisos (1) that when Q is
    where when X is a hydrogen atom and Y, is an alkyl group, Z is not a hydrogen atom, a halogen atom nor a trifluoromethyl group, and (2) that when Q is
    wherein A is a nitrogen atom and Y, is a trifluoromethyl group, Y 2 is other than a hydrogen atom.

    An O-(N-alkoxy-pyridinecarboximidoyl)phosphate, a process for producing the same, and an insecticidal or acaricidal composition containing the same
    7.
    发明公开
    An O-(N-alkoxy-pyridinecarboximidoyl)phosphate, a process for producing the same, and an insecticidal or acaricidal composition containing the same 失效
    O-（N-烷氧基 - pyridincarboximidoyl）磷酸酯，其制备方法和杀虫或含有它的杀螨组合物的方法。

    公开(公告)号：EP0065039A1

    公开(公告)日：1982-11-24

    申请号：EP81302009.6

    申请日：1981-05-07

    申请人： ISHIHARA SANGYO KAISHA LTD.

    发明人： Takahiro, Haga ,  Tadaaki, Toki ,  Toru, Koyanagi ,  Osamu, Imai

    IPC分类号： C07F9/58 ,  A01N57/16 ,  A01N57/24 ,  A01N57/32

    CPC分类号： C07D213/78 ,  A01N57/08 ,  C07F9/582

    摘要： An O-(N-alkoxy-pyridinecarboximidoyl)-phosphate is represented by the following formula:
    wherein X is a halogen atom, a lower alkyl group, a lower acyloxy group. a trifluoromethyl group or a nitro group; Y is an oxygen atom or a sulfur atom; R is a lower alkyl group; n is an integer of 0 to 3; and Z 1 and Z 2 are each a lower alkoxy group, a lower alkylthio group, a phenyl group which may be substituted by a lower alkyl group, a phenoxy group, a haloalkoxy group or a lower alkylamino group.
    The compound of formula (I) is useful as an active ingredient of insecticides or acaricides and is produced by reacting an N-alkoxy-pyridinecarboximidic acid having the formula (A):
    wherein X, R and n are as defined above with a phosphoric halide having the formula (B):
    wherein Hal is a halogen atom and Y, Z, and Z. are as defined above in the presence of an alkaline material.

    摘要翻译： O-（N-alkoxypyridinecarboximidoyl）磷酸酯由下式表示： worin X是卤原子，低级烷基，低级酰氧基，三氟甲基或硝基; Y是氧原子或硫原子; R是低级烷基; n为0〜3的整数; Z1和Z2各自为一个低级烷氧基，低级烷硫基，可被低级烷基，苯氧基，卤代烷氧基或低级烷基氨基取代的苯基。 式（I）的化合物可用作在杀虫剂或杀螨剂的活性成分，并通过使成N-烷氧基 - pyridinecarboximidic酸具有下式（A）制备： worin X，R和n如以上所定义 具有式（B）磷酸卤化物： worin Hal为卤原子，Y，Z 1和Z 2如上述在碱性物质的存在下定义。

    A 2-amino-trifluoromethyl-halogenopyridine compound and a process for producing the same
    8.
    发明公开
    A 2-amino-trifluoromethyl-halogenopyridine compound and a process for producing the same 失效
    2-氨基 - 三氟甲基 - 卤素吡啶 - Verbindung和Verfahren zu deren Herstellung。

    公开(公告)号：EP0031218A1

    公开(公告)日：1981-07-01

    申请号：EP80304466.8

    申请日：1980-12-11

    申请人： ISHIHARA SANGYO KAISHA LTD.

    发明人： Isao, Yokomichi ,  Takahiro, Haga ,  Kuniaki, Nagatani ,  Toshio, Nakajima

    IPC分类号： C07D213/73

    CPC分类号： C07D213/73 ,  A01N43/40 ,  C07D213/75

    摘要： A 2-amino-trifluoromethyl-halogenopyridine compound is characterised by the formula (I):
    wherein either X or Y is a trifluoromethyl group, and at least one of X, Y and Z is a halogen atom, with the remainder being a halogen atom or a hydrogen atom. The compound of formula (I) is prepard by amination of a 2-halogenotrifluoromethyl-halogenopyridine or by halogenation of 2-amino- trifluoromethylpyridine and is useful as an intermediate for synthesis of agricultural chemicals and medicines.

    摘要翻译： 2-氨基 - 三氟甲基 - 卤代吡啶化合物的特征在于式（1）：其中X或Y为三氟甲基，X，Y和Z中的至少一个为卤素原子，其余为 卤素原子或氢原子。 式（1）化合物通过2-卤代三氟甲基 - 卤代吡啶的胺化或通过2-氨基 - 三氟甲基吡啶的卤化来制备，并且可用作合成农药和药物的中间体。