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公开(公告)号：EP3380513A1
公开(公告)日：2018-10-03
申请号：EP16805186.0
申请日：2016-11-23
发明人： POWLESLAND, Alex , DE SOUZA, Victoria Arena , CHILLAKURI, Chandramouli , SANGANI, Dhaval , HOOD, Graham , OESTRINGER, Benjamin
CPC分类号： A61K39/001111 , A61K39/0011 , A61K47/6849 , A61K2039/5158 , A61K2039/605 , A61P35/00 , C07K14/71 , G01N33/505 , G01N33/574
摘要： The present invention relates to novel peptides derived from Neuropeptide S Receptor (NPSR1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380510A1
公开(公告)日：2018-10-03
申请号：EP16805182.9
申请日：2016-11-23
IPC分类号： C07K14/705 , C07K7/04 , C07K14/47
CPC分类号： C07K14/70539 , A61K38/00 , A61K39/0011 , A61P35/00 , C07K4/12 , C07K7/06 , C07K7/08 , C07K14/4748 , C07K14/7051 , C07K14/70571
摘要： The present invention relates to novel peptides derived from 5-hydroxytryptamine receptor 3A (HTR3A), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380498A1
公开(公告)日：2018-10-03
申请号：EP16805177.9
申请日：2016-11-23
CPC分类号： A61K38/1774 , A61K35/17 , A61K38/03 , A61K39/0011 , A61P35/00 , C07K14/4748 , C07K14/7051 , C12N15/62 , C12N15/79
摘要： The present invention relates to novel peptides derived from Kita-kyushu lung cancer antigen (CT83), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380489A1
公开(公告)日：2018-10-03
申请号：EP16805183.7
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina
CPC分类号： C07K7/06 , A61K39/0011 , A61K2039/605 , C07K14/7051 , C07K14/70539
摘要： The present invention relates to novel peptides derived from DDB1- and CUL4-associated factor 4-like protein 2 (DCAF4L2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380509A1
公开(公告)日：2018-10-03
申请号：EP16805179.5
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina , SUN, Meidai
CPC分类号： C07K14/64 , A61K38/00 , A61P35/00 , C07K7/06 , C07K7/08 , C07K14/7051 , C07K14/70539 , C07K19/00 , C40B40/02 , G01N2333/70539
摘要： The present invention relates to novel peptides derived from Prorelaxin H1 (RLN1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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7.发明公开
公开(公告)号：EP3380505A1
公开(公告)日：2018-10-03
申请号：EP16805196.9
申请日：2016-11-23
发明人： POWLESLAND, Alex , POPA, Alina
IPC分类号： C07K14/47
CPC分类号： C07K14/4748 , C07K14/7051 , C07K14/70539 , C07K16/18 , C07K2319/00 , G01N33/574
摘要： The present invention relates to novel peptides derived from Achaete-scute homolog 2 (ASCL2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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8.发明公开
公开(公告)号：EP3380504A1
公开(公告)日：2018-10-03
申请号：EP16805195.1
申请日：2016-11-23
发明人： POWLESLAND, Alex , SUN, Meidai
CPC分类号： A61K39/001114 , A61K39/0011 , A61P35/00 , C07K14/4748 , C07K16/2833
摘要： The present invention relates to novel peptides derived from Homeobox protein Hox-B13 (HOXB13), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380491A1
公开(公告)日：2018-10-03
申请号：EP16805187.8
申请日：2016-11-23
发明人： POWLESLAND, Alex , SUN, Meidai , KLEIJNEN, Maurits
IPC分类号： C07K7/06
CPC分类号： C07K7/08 , A61K38/00 , A61P35/00 , C07K7/06 , C07K14/705 , C07K14/7051 , C07K14/70539
摘要： The present invention relates to novel peptides derived from solute carrier family 45 member 2 (SLC45A2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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公开(公告)号：EP3380488A1
公开(公告)日：2018-10-03
申请号：EP16804852.8
申请日：2016-11-23
发明人： POWLESLAND, Alex , CHESTER, Fiona
CPC分类号： C07K4/12 , A61K38/00 , A61K39/0011 , A61K2039/605 , A61P35/00 , C07K7/06 , C07K7/08 , C07K14/7051 , C07K14/70539
摘要： The present invention relates to novel peptides derived from melanoma-associated antigen C2 (MAGEC2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
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