公开(公告)号：EP2023941B1

公开(公告)日：2016-12-21

申请号：EP07755963.1

申请日：2007-04-24

申请人： Incept, LLC

发明人： PATHAK, Chandrashekhar, P. ,  SAWHNEY, Amarpreet, S. ,  DREHER, James, H.

IPC分类号： A61K31/74 ,  C07K14/00 ,  C08F283/00

CPC分类号： A61L24/0005 ,  A61K47/60 ,  A61L24/0031 ,  A61L24/046 ,  A61L24/06 ,  A61L24/108 ,  C08H1/00 ,  C08L89/00 ,  C08L71/02 ,  C08L39/06

公开(公告)号：EP1945129A2

公开(公告)日：2008-07-23

申请号：EP06815999.5

申请日：2006-09-29

申请人： Incept, LLC

发明人： DREHER, James, H. ,  SALAHIEH, Amr ,  KROLIK, Jeffrey

IPC分类号： A61F2/00

CPC分类号： A61F2/958 ,  A61F2002/821 ,  A61F2250/0039

摘要： Apparatus (10) for locating an ostium of a branch vessel includes a delivery- catheter (12) having a distal end (16) sized for introduction into the branch, and locator elements (50) including first ends (52) fixed to the distal end (16) and second ends (54) free from the distal end (16). The locator elements (50) are compressible from a transverse, deployed condition to an axial, contracted condition, wherein the second ends (54) are disposed proximal to the first ends (52). The catheter (12) may be used to deliver a stent (40) into the branch with the expanded locator element (50) facilitating positioning the stent (40).

公开(公告)号：EP2320810A2

公开(公告)日：2011-05-18

申请号：EP09805648.4

申请日：2009-08-08

申请人： Incept, Llc

发明人： KROLIK, Jeffrey, A. ,  DREHER, James, H. ,  WATANABE, Gwendolyn

IPC分类号： A61B17/22 ,  A61M25/10

CPC分类号： A61B17/320725 ,  A61B17/22 ,  A61B2017/22001 ,  A61B2017/22054 ,  A61B2017/22061 ,  A61B2017/22067 ,  A61B2017/22068 ,  A61B2017/22069 ,  A61B2017/22072 ,  A61B2017/22079 ,  A61B2017/2215 ,  A61M25/04 ,  A61M25/09 ,  A61M25/1002 ,  A61M25/104

摘要： Apparatus are provided for accessing and/or removing material from a body lumen. The apparatus includes a tubular sheath including a shaft having a proximal end and an expandable distal end that is expandable between a collapsed configuration and an expanded, tapered configuration. In one embodiment, the expandable member include inner and outer membranes attached together and to the shaft. Optionally, the inner membrane may include a reinforcement layer and/or the outer membrane may have a longer chord length than the inner membrane, to enhance the expandable member expanding such that a distal opening is defined by the expandable member having s a relatively large diameter tapering proximally to a lumen of the shaft. Optionally, the apparatus may include a dilator and/or one or more treatment devices receivable in the lumen of the shaft.

公开(公告)号：EP2023941A2

公开(公告)日：2009-02-18

申请号：EP07755963.1

申请日：2007-04-24

申请人： Incept, LLC

发明人： PATHAK, Chandrashekhar, P. ,  SAWHNEY, Amarpreet, S. ,  DREHER, James, H.

IPC分类号： A61K31/74

CPC分类号： A61L24/0005 ,  A61K47/60 ,  A61L24/0031 ,  A61L24/046 ,  A61L24/06 ,  A61L24/108 ,  C08H1/00 ,  C08L89/00 ,  C08L71/02 ,  C08L39/06

摘要： Some aspects of this disclosure relate to a method for crosslinking a biological fluid comprising combining a biological fluid with a crosslinker to covalently crosslink proteins endogenous to the biological fluid to form a crosslinked gel. Examples of a biological fluid are blood, plasma, or serum.

公开(公告)号：EP1906877A1

公开(公告)日：2008-04-09

申请号：EP06771082.2

申请日：2006-05-23

申请人： INCEPT LLC

发明人： KROLIK, Jeff ,  KIM, Elliot ,  DREHER, James, H.

IPC分类号： A61F2/06

CPC分类号： A61F2/915 ,  A61B2090/3966 ,  A61F2/91 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/821 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/0091 ,  A61F2250/0039

摘要： Apparatus and methods are provided for locating an ostium of a body lumen. In one embodiment, a delivery catheter (10) or other tubular member includes a distal end sized for introduction into a body lumen, and one or more locator loops (50) on the distal end. In one embodiment, the locator loop may include first and second ends fixed to the distal end, first and second resilient struts extending from the first and second ends, respectively, and a curved intermediate region extending between the first and second struts. The loop may be resiliently compressible to a contracted condition for delivery and resiliently expandable to an enlarged condition when deployed. The apparatus may include one or more balloons, stents (40) , and the like on the distal end adjacent the locator loop.

摘要翻译： 提供了用于定位体腔的开口的设备和方法。 在一个实施例中，输送导管（10）或其他管状构件包括大小适合引入体腔的远端和远端上的一个或多个定位器环（50）。 在一个实施例中，定位器环可以包括固定到远端的第一和第二端，分别从第一和第二端延伸的第一和第二弹性支柱以及在第一和第二支柱之间延伸的弯曲中间区。 该环可以弹性地压缩至收缩状态以便输送并且在展开时可弹性扩张至扩大状态。 该装置可以在与定位器环相邻的远端上包括一个或多个气囊，支架（40）等。