公开(公告)号：EP1442064A2

公开(公告)日：2004-08-04

申请号：EP02801802.6

申请日：2002-10-17

申请人： Incyte Genomics, Inc.

发明人： BANDMAN, Olga ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  BOROWSKY, Mark, L. ,  DUGGAN, Brendan, M. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GANDHI, Ameena, R. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  GURURAJAN, Rajagopal ,  HAFALIA, April, J.A. ,  KHAN, Farrah, A. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  LEE, Soo, Yeun ,  LINDQUIST, Erika, A. ,  LU, Dyung Aina, M. ,  LU, Yan ,  MARQUIS, Joseph, P. ,  NGUYEN, Danniel, B. ,  ARVIZU, Chandra S. ,  RAMUKAR, Jayalaxmi ,  RECIPON, Shirley A. ,  RICHARDSON, Thomas, W. ,  SWARNAKAR, Anita ,  TANG, Y., Tom ,  THORNTON, Michael ,  TRAN, Uyen, K. ,  CHAWLA, Narinder, K. ,  WARREN, Bridget A. ,  YANG, Junming ,  YAO, Monique G. ,  YUE, Henry ,  ZEBARJADIAN, Yeganeh

IPC分类号： C07K16/00 ,  A61K38/00

CPC分类号： C12N9/1205 ,  A01K2217/05

摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与KPP异常表达相关的病症的方法。

公开(公告)号：EP1506303A2

公开(公告)日：2005-02-16

申请号：EP02792403.4

申请日：2002-12-12

申请人： Incyte Genomics, Inc.

发明人： CHAWLA, Narinder, K. ,  LEE, Soo, Yeun ,  RING, Huijun, Z. ,  LEE, Ernestine, A. ,  FORSYTHE, Ian, J. ,  KHARE, Reena ,  TRAN, Uyen, K. ,  KABLE, Amy, E. ,  RICHARDSON, Thomas, W. ,  EMERLING, Brooke, M. ,  LINDQUIST, Erika, A. ,  BAUGHN, Mariah, R. ,  HAFALIA, April, J.A. ,  JIN, Pei ,  SWARNAKAR, Anita ,  LI, Joana, X. ,  MARQUIS, Joseph, P. ,  LEE, Sally ,  GORVAD, Ann, E. ,  SPRAGUE, William W. ,  BECHA, Shanya D. ,  ELLIOTT, Vicki S.

IPC分类号： C12P21/06 ,  C12N9/00 ,  C12N1/20 ,  C12N15/00 ,  C07H21/02 ,  C07H21/04

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C12N9/00

摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码ENZM的人类酶（ENZM）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与ENZM的异常表达相关的病症的方法。

公开(公告)号：EP1504101A2

公开(公告)日：2005-02-09

申请号：EP02786702.7

申请日：2002-11-07

申请人： Incyte Genomics, Inc.

发明人： KABLE, Amy, E. ,  SWARNAKAR, Anita ,  GORVAD, Ann, E. ,  HAFALIA, April, J.A. ,  DUGGAN, Brendan, M. ,  WARREN, Bridget, A. ,  EMERLING, Brooke, M. ,  ISON, Craig, H. ,  NGUYEN, Danniel, B. ,  LINDQUIST, Erika, A. ,  LEE, Ernestine, A. ,  YUE, Henry ,  YUE, Huibin ,  FORSYTHE, Ian, J. ,  RAMKUMAR, Jayalaxmi ,  GRIFFIN, Jennifer, A. ,  LI, Joana, X. ,  MARQUIS, Joseph, P. ,  GIETZEN, Kimberly, J. ,  BAUGHN, Mariah R. ,  BOROWSKY, Mark L. ,  YAO, Monique G. ,  CHAWLA, Narinder K. ,  LEHR-MASON, Patricia M. ,  LAL, Preeti G. ,  GURURAJAN, Rajagopal ,  KHARE, Reena ,  BATRA, Sajeev ,  BECNA, Shanya, D. ,  LEE, Soo Yeun ,  TRAN, Uyen K. ,  ELLIOTT, Vicki S. ,  SPRAGUE, William W. ,  TANG, Y. Tom ,  ZEBARJADIAN, Yeganeh ,  JIANG, Xin ,  JACKSON, Alan A. ,  BHATIA, Umesh ,  BURRILL, John D. ,  LEE, Sally ,  BLAKE, Julie J. ,  HO, Anne ,  ZHENG, Wenjin

IPC分类号： C12N15/63 ,  C12N15/85 ,  C07K14/00 ,  C07K16/00

CPC分类号： C07K14/47

摘要： Various ernbodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.