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公开(公告)号:EP1451212A2
公开(公告)日:2004-09-01
申请号:EP02780462.4
申请日:2002-10-10
发明人: BECHA, Shanya, D. , BHATIA, Umesh , BLAKE, Julie, J. , BOROWSKY, Mark, L. , BURRILL, John, D. , CHANG, Hsin-Ru , CHAWLA, Narinder, K. , ELLIOTT, Vicki, S. , EMERLING, Brooke, M. , FORSYTHE, Ian, J. , GORVAD, Ann, E. , GRIFFIN, Jennifer, A. , HAFALIA, April, J., A. , HO, Anne , ISON, Craig, H. , KABLE, Amy, E. , KHARE, Reena , LAL, Preeti, G. , LEE, Sally , LEE, Ernestine A. , LEE, Soo Yeun , LEHR-MASON, Patricia M. , LI, Joana X. , LINDQUIST, Erika A. , LUO, Wen , MARQUIS, Joseph P. , RAMKUMAR, Jayalaxmi , RICHARDSON, Thomas W. , SPRAGUE, William W. , SWARNAKAR, Anita , TANG, Y. Tom , WARREN, Bridget A. , YANG, Junming , YUE, Henry , ZEBARJADIAN, Yeganeh , ZHENG, Wenjin
摘要: Various embodiments of the invention provide human structural and cytoskeleton-associated proteins (SCAP) and polynucleotides which identify and encode SCAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SCAP.
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公开(公告)号:EP1423511A2
公开(公告)日:2004-06-02
申请号:EP02761367.8
申请日:2002-08-14
发明人: BARROSO, Ines , BAUGHN, Mariah, R. , BECHA, Shanya, D. , BLAKE, Julie, J. , BOROWSKY, Mark, L. , BURFORD, Neil , DUGGAN, Brendan, M. , ELLIOTT, Vicki, S. , EMERLING, Brooke, M. , FORSYTHE, Ian, J. , GIETZEN, Kimberly, J. , GORVAD, Ann, E. , GRIFFIN, Jennifer, A. , HAFALIA, April, J.A. , HONCHELL, Cynthia, D. , ISON, Craig, H. , KHAN, Farrah, A. , LAL, Preeti, G. , LEE, Ernestine, A. , LEE, Sally , LEE, Soo Yeun , LI, Joana X. , LU, Dyung Aina M. , LU, Yan , LEHR-MASON, Patricia M. , NGUYEN, Danniel B. , RAMKUMAR, Jayalaxmi , SPRAGUE, William W. , TANG, Y. Tom , THANGAVELU, Kavitha , THORNTON, Michael , TRAN, Uyen K. , CHAWLA, Narinder K. , WARREN, Bridget A. , XU, Yuming , YAO, Monique G. , YUE, Henry , YUE, Huibin , ZEBARJADIAN, Yeganeh
CPC分类号: C07K14/4702 , A61K38/00 , G01N2500/00
摘要: Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译: 本发明的各种实施方案提供了鉴定和编码NAAP的人核酸相关蛋白(NAAP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供了用于诊断,治疗或预防与NAAP的异常表达相关的病症的方法。
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公开(公告)号:EP1463818A2
公开(公告)日:2004-10-06
申请号:EP02805100.1
申请日:2002-12-10
发明人: BAUGHN, Mariah, R. , CHANG, Hsin-Ru , CHIEN, David , DUGGAN, Brendan, M. , EMERLING, Brooke, M. , GORVAD, Ann, E. , GRIFFIN, Jennifer, A. , HAFALIA, April, J.A. , HAWKINS, Phillip, R. , JACKSON, Alan, A. , JIANG, Xin , JIN, Pei , KABLE, Amy, E. , KHARE, Reena , LAL, Preeti, G. , LEE, Ernestine, A. , LEE, Sally , LEE, Soo, Yeun , RAMKUMAR, Jayalaxmi , REDDY, Roopa , RICHARDSON, Thomas W. , RING, Huijun Z. , SPRAGUE, William W. , SWARNAKAR, Anita , TANG, Y. Tom , ZEBARJADIAN, Yeganeh
CPC分类号: C07K14/705
摘要: Various embodiments of the invention provide human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
摘要翻译: 本发明的各种实施方式提供了识别和编码TRICH的人转运蛋白和离子通道(TRICH)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与TRICH的异常表达相关的病症的方法。
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公开(公告)号:EP1444254A2
公开(公告)日:2004-08-11
申请号:EP02784109.7
申请日:2002-10-10
发明人: TANG, Y. , Tom , FORSYTHE, Ian, J. , EMERLING, Brooke, M. , HAFALIA, April, J., A. , YUE, Henry , XU, Yuming , GIETZEN, Kimberly, J. , CHAWLA, Narinder, K. , BAUGHN, Mariah, R. , MARQUIS, Joseph, P. , BECHA, Shanya, D. , KABLE, Amy, E. , LAL, Preeti, G. , RICHARDSON, Thomas, W. , LEE, Soo, Yeun , LEE, Ernestine, A. , TRAN, Bao , WARREN, Bridget, A. , LU, Dyung Aina, M. , GURURAJAN, Rajagopal , SPRAGUE, William W. , BLAKE, Julie J. , THANGAVELU, Kavitha , SWARNAKAR, Anita , GORVAD, Ann E. , GRIFFIN, Jennifer A. , LINDQUIST, Erika A. , ELLIOTT, Vicki S. , ISON, Craig H. , RAMKUMAR, Jayalaxmi
IPC分类号: C07K14/00
CPC分类号: C07K14/47
摘要: Various embodiments of the invention provide human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.
摘要翻译: 本发明的各种实施方式提供了用于疾病检测和治疗的人分子(MDDT)和鉴定和编码MDDT的多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供了用于诊断,治疗或预防与MDDT的异常表达相关的病症的方法。
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公开(公告)号:EP1421111A2
公开(公告)日:2004-05-26
申请号:EP02757071.2
申请日:2002-08-08
发明人: AZIMZAI, Yalda , BARROSO, Ines , BAUGHN, Mariah, R. , BECHA, Shanya, D. , BOROWSKY, Mark, L. , DUGGAN, Brendan, M. , ELLIOTT, Vicki, S. , EMERLING, Brooke, M. , FORSYTHE, Ian, J. , GIETZEN, Kimberly, J. , GORVAD, Ann, E. , GRAUL, Richard, C. , GRIFFIN, Jennifer, A. , GURURAJAN, Rajagopal , HAFALIA, April, J.A. , ISON, Craig, H. , KABLE, Amy, E. , KHAN, Farrah, A. , LEE, Sally , LEE, Soo Yeun , LI, Joana X. , REDDY, Roopa , RICHARDSON, Thomas W. , SPRAGUE, William W. , SWARNAKAR, Anita , TANG, Y. Tom , WARREN, Bridget A. , XU, Yuming , YAO, Monique G. , YUE, Henry , YUE, Huibin
IPC分类号: C07K14/435 , C12N15/12 , A61K38/17
CPC分类号: C07K14/47 , C07K14/4747 , C07K14/4748 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/6872 , G01N2333/47
摘要: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
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公开(公告)号:EP1506303A2
公开(公告)日:2005-02-16
申请号:EP02792403.4
申请日:2002-12-12
发明人: CHAWLA, Narinder, K. , LEE, Soo, Yeun , RING, Huijun, Z. , LEE, Ernestine, A. , FORSYTHE, Ian, J. , KHARE, Reena , TRAN, Uyen, K. , KABLE, Amy, E. , RICHARDSON, Thomas, W. , EMERLING, Brooke, M. , LINDQUIST, Erika, A. , BAUGHN, Mariah, R. , HAFALIA, April, J.A. , JIN, Pei , SWARNAKAR, Anita , LI, Joana, X. , MARQUIS, Joseph, P. , LEE, Sally , GORVAD, Ann, E. , SPRAGUE, William W. , BECHA, Shanya D. , ELLIOTT, Vicki S.
CPC分类号: C07K14/4702 , A61K38/00 , C12N9/00
摘要: Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.
摘要翻译: 本发明的各种实施方案提供了鉴定和编码ENZM的人类酶(ENZM)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供了用于诊断,治疗或预防与ENZM的异常表达相关的病症的方法。
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公开(公告)号:EP1504101A2
公开(公告)日:2005-02-09
申请号:EP02786702.7
申请日:2002-11-07
发明人: KABLE, Amy, E. , SWARNAKAR, Anita , GORVAD, Ann, E. , HAFALIA, April, J.A. , DUGGAN, Brendan, M. , WARREN, Bridget, A. , EMERLING, Brooke, M. , ISON, Craig, H. , NGUYEN, Danniel, B. , LINDQUIST, Erika, A. , LEE, Ernestine, A. , YUE, Henry , YUE, Huibin , FORSYTHE, Ian, J. , RAMKUMAR, Jayalaxmi , GRIFFIN, Jennifer, A. , LI, Joana, X. , MARQUIS, Joseph, P. , GIETZEN, Kimberly, J. , BAUGHN, Mariah R. , BOROWSKY, Mark L. , YAO, Monique G. , CHAWLA, Narinder K. , LEHR-MASON, Patricia M. , LAL, Preeti G. , GURURAJAN, Rajagopal , KHARE, Reena , BATRA, Sajeev , BECNA, Shanya, D. , LEE, Soo Yeun , TRAN, Uyen K. , ELLIOTT, Vicki S. , SPRAGUE, William W. , TANG, Y. Tom , ZEBARJADIAN, Yeganeh , JIANG, Xin , JACKSON, Alan A. , BHATIA, Umesh , BURRILL, John D. , LEE, Sally , BLAKE, Julie J. , HO, Anne , ZHENG, Wenjin
CPC分类号: C07K14/47
摘要: Various ernbodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
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公开(公告)号:EP1480994A1
公开(公告)日:2004-12-01
申请号:EP02792392.9
申请日:2002-12-12
发明人: BAUGHN, Mariah, R. , BHATIA, Umesh , BLAKE, Julie, J. , BURRILL, John, D. , ELLIOTT, Vicki, S. , EMERLING, Brooke, M. , FORSYTHE, Ian, J. , GIETZEN, Kimberly, J. , GORVAD, Ann, E. , GRIFFIN, Jennifer, A. , HAFALIA, April, J.A. , HO, Anne , JACKSON, Alan, A. , JIANG, Xin , KABLE, Amy, E. , KEARNEY, Liam , KHARE, Reena , LEE, Ernestine, A. , LEE, Sally , LU, Dyung Aina M. , MARQUIS, Joseph P. , LEHR-MASON, Patricia M. , RAMKUMAR, Jayalaxmi , RICHARDSON, Thomas W. , SPRAGUE, William W. , TRAN, Uyen K. , CHAWLA, Narinder K. , WARREN, Bridget A. , YUE, Henry , ZHENG, Wenjin
CPC分类号: C07K14/47
摘要: Various embodiments of the invention provide human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.
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公开(公告)号:EP1423415A2
公开(公告)日:2004-06-02
申请号:EP02793765.5
申请日:2002-08-16
发明人: YUE, Henry , LU, Dyung Aina, M. , SWARNAKAR, Anita , TANG, Y., Tom , GRIFFIN, Jennifer, A. , EMERLING, Brooke, M. , FORSYTHE, Ian, J. , YAO, Monique, G. , RAMKUMAR, Jayalaxmi , RICHARDSON, Thomas, W. , BECHA, Shanya, D. , LEE, Ernestine, A. , WARREN, Bridget, A. , LEHR-MASON, Patricia, M. , BAUGHN, Mariah, R. , LI, Joana, X. , DUGGAN, Brendan, M. , GIETZEN, Kimberly, J. , LAL, Preeti, G. , BOROWSKY, Mark L. , ISON, Craig H. , THANGAVELU, Kavitha , XU, Yuming , LEE, Sally , ELLIOTT, Vicki S. , SPRAGUE, William W. , AZIMZAI, Yalda , HAFALIA, April J.A. , DING, Li , NGUYEN, Danniel B. , HONCHELL, Cynthia D. , LUO, Wen , CHWALA, Narinder K. , MARQUIS, Joseph P. , JACKSON, Jennifer L. , TRAN, Uyen K.
IPC分类号: C07K14/00
CPC分类号: C07K14/4702 , A61K38/00 , C07K14/47 , G01N2500/04
摘要: Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译: 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子(INTSIG)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供了用于诊断,治疗或预防与INTSIG的异常表达相关的病症的方法。
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