公开(公告)号：EP1463818A2

公开(公告)日：2004-10-06

申请号：EP02805100.1

申请日：2002-12-10

申请人： Incyte Genomics, Inc.

发明人： BAUGHN, Mariah, R. ,  CHANG, Hsin-Ru ,  CHIEN, David ,  DUGGAN, Brendan, M. ,  EMERLING, Brooke, M. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J.A. ,  HAWKINS, Phillip, R. ,  JACKSON, Alan, A. ,  JIANG, Xin ,  JIN, Pei ,  KABLE, Amy, E. ,  KHARE, Reena ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  LEE, Sally ,  LEE, Soo, Yeun ,  RAMKUMAR, Jayalaxmi ,  REDDY, Roopa ,  RICHARDSON, Thomas W. ,  RING, Huijun Z. ,  SPRAGUE, William W. ,  SWARNAKAR, Anita ,  TANG, Y. Tom ,  ZEBARJADIAN, Yeganeh

IPC分类号： C12N15/12 ,  C12N15/63 ,  C12N15/00 ,  C07H21/04 ,  C07K14/00

CPC分类号： C07K14/705

摘要： Various embodiments of the invention provide human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

摘要翻译： 本发明的各种实施方式提供了识别和编码TRICH的人转运蛋白和离子通道（TRICH）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与TRICH的异常表达相关的病症的方法。

公开(公告)号：EP1456655A2

公开(公告)日：2004-09-15

申请号：EP02804422.0

申请日：2002-11-13

申请人： Incyte Genomics, Inc.

发明人： DUGGAN, Brendan, M. ,  YANG, Junming ,  GIETZEN, Kimberly, J. ,  LEE, Soo, Yeun ,  TANG, Y. , Tom ,  AZIMZAI, Yalda ,  CHAWLA, Narinder, K. ,  WARREN, Bridget, A. ,  BARROSO, Ines ,  BECHA, Shanya, D. ,  YUE, Henry ,  LEHR-MASON, Patricia, M. ,  THANGAVELU, Kavitha ,  LEE, Sally ,  EMERLING, Brooke, M. ,  KABLE, Amy, E. ,  KHARE, Reena ,  BAUGHN, Mariah, R. ,  GANDHI, Ameena, R. ,  TRAN, Uyen, K. ,  RICHARDSON, Thomas, W. ,  MARQUIS, Joseph, P. ,  LAL, Preeti, G. ,  FORSYTHE, Ian,J. ,  LEE, Ernestine, A. ,  SWARNAKAR, Anita ,  KALLICK, Deborah, A. ,  GRIFFIN, Jennifer, A. ,  ELLIOTT, Vicki, S. ,  GORVAD, Ann, E. ,  HALFALIA, April, J.A. ,  ISON, Craig, H. ,  JIN, Pei ,  JIANG, Xin ,  JACKSON, Alan, A. ,  BHATIA, Umesh ,  BURRILL, John, D. ,  BLAKE, Julie, J. ,  HO, Anne ,  ZHENG, Wenijn ,  GAO, Jing

IPC分类号： G01N33/53 ,  C07H21/02 ,  C07H21/04

CPC分类号： C07K14/705 ,  C07K14/47

摘要： Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.

摘要翻译： 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与REMAP异常表达相关的病症的方法。

公开(公告)号：EP1444255A2

公开(公告)日：2004-08-11

申请号：EP02806690.0

申请日：2002-10-24

申请人： Incyte Genomics, Inc.

发明人： BAUGHN, Mariah, R. ,  LEE, Ernestine, A. ,  ELLIOTT, Vicki, S. ,  DUGGAN, Brendan, M. ,  LI, Joana, X. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J.A. ,  DELEGEANE, Angelo, M. ,  LEE, Soo, Yeun ,  BECHA, Shanya, D. ,  RAMKUMAR, Jayalaxmi ,  KABLE, Amy, E. ,  MARQUIS, Joseph, P. ,  GURURAJAN, Rajagopal ,  SPRAGUE, William, W. ,  YANG, Junming ,  GIETZEN, Kimberly, J. ,  ZEBARJADIAN, Yeganeh ,  RICHARDSON, Thomas, W. ,  JIANG, Xin

IPC分类号： C07K14/00

CPC分类号： C07K14/47 ,  A61K38/00

摘要： Various embodiments of the invention provide human vesicle-associatedproteins (VAP) and polynucleotides which identify and encode VAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of VAP.

公开(公告)号：EP1368473A2

公开(公告)日：2003-12-10

申请号：EP02718986.9

申请日：2002-02-15

申请人： Incyte Genomics, Inc.

发明人： DUGGAN, Brendan, M. ,  HONCHELL, Cynthia, D. ,  ISON, Craig, H. ,  THANGAVELU, Kavitha ,  LU, Dyung Aina, M. ,  BAUGHN, Mariah, R. ,  LAL, Preeti, G. ,  YUE, Henry ,  TANG, Y., Tom ,  WARREN, Bridget, A. ,  LEE, Ernestine, A. ,  GRIFFIN, Jennifer, A. ,  FORSYTHE, Ian, J. ,  CHAWLA, Narinder, K. ,  JIANG, Xin ,  JACKSON, Alan, A.

IPC分类号： C12N15/12 ,  C07K14/705 ,  C07K16/28 ,  A01K67/027 ,  C12Q1/68 ,  G01N33/577 ,  G01N33/68 ,  A61K38/17 ,  A61K39/395 ,  A61P25/00

CPC分类号： C07K14/705 ,  A01K2217/05 ,  A61K38/00 ,  A61K2039/505

摘要： The invention provides human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.

公开(公告)号：EP1504101A2

公开(公告)日：2005-02-09

申请号：EP02786702.7

申请日：2002-11-07

申请人： Incyte Genomics, Inc.

发明人： KABLE, Amy, E. ,  SWARNAKAR, Anita ,  GORVAD, Ann, E. ,  HAFALIA, April, J.A. ,  DUGGAN, Brendan, M. ,  WARREN, Bridget, A. ,  EMERLING, Brooke, M. ,  ISON, Craig, H. ,  NGUYEN, Danniel, B. ,  LINDQUIST, Erika, A. ,  LEE, Ernestine, A. ,  YUE, Henry ,  YUE, Huibin ,  FORSYTHE, Ian, J. ,  RAMKUMAR, Jayalaxmi ,  GRIFFIN, Jennifer, A. ,  LI, Joana, X. ,  MARQUIS, Joseph, P. ,  GIETZEN, Kimberly, J. ,  BAUGHN, Mariah R. ,  BOROWSKY, Mark L. ,  YAO, Monique G. ,  CHAWLA, Narinder K. ,  LEHR-MASON, Patricia M. ,  LAL, Preeti G. ,  GURURAJAN, Rajagopal ,  KHARE, Reena ,  BATRA, Sajeev ,  BECNA, Shanya, D. ,  LEE, Soo Yeun ,  TRAN, Uyen K. ,  ELLIOTT, Vicki S. ,  SPRAGUE, William W. ,  TANG, Y. Tom ,  ZEBARJADIAN, Yeganeh ,  JIANG, Xin ,  JACKSON, Alan A. ,  BHATIA, Umesh ,  BURRILL, John D. ,  LEE, Sally ,  BLAKE, Julie J. ,  HO, Anne ,  ZHENG, Wenjin

IPC分类号： C12N15/63 ,  C12N15/85 ,  C07K14/00 ,  C07K16/00

CPC分类号： C07K14/47

摘要： Various ernbodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.

公开(公告)号：EP1480994A1

公开(公告)日：2004-12-01

申请号：EP02792392.9

申请日：2002-12-12

申请人： Incyte Genomics, Inc.

发明人： BAUGHN, Mariah, R. ,  BHATIA, Umesh ,  BLAKE, Julie, J. ,  BURRILL, John, D. ,  ELLIOTT, Vicki, S. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GIETZEN, Kimberly, J. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J.A. ,  HO, Anne ,  JACKSON, Alan, A. ,  JIANG, Xin ,  KABLE, Amy, E. ,  KEARNEY, Liam ,  KHARE, Reena ,  LEE, Ernestine, A. ,  LEE, Sally ,  LU, Dyung Aina M. ,  MARQUIS, Joseph P. ,  LEHR-MASON, Patricia M. ,  RAMKUMAR, Jayalaxmi ,  RICHARDSON, Thomas W. ,  SPRAGUE, William W. ,  TRAN, Uyen K. ,  CHAWLA, Narinder K. ,  WARREN, Bridget A. ,  YUE, Henry ,  ZHENG, Wenjin

IPC分类号： C07H21/04 ,  C12N15/00 ,  C12N15/85 ,  C12N15/86 ,  C07K5/00 ,  C07K14/00 ,  A61K38/00

CPC分类号： C07K14/47

摘要： Various embodiments of the invention provide human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.

公开(公告)号：EP1434860A2

公开(公告)日：2004-07-07

申请号：EP02783990.1

申请日：2002-09-26

申请人： Incyte Genomics, Inc.

发明人： YANG, Junming ,  LU, Dyung Aina, M. ,  YUE, Henry ,  ELLIOTT, Vicki, S. ,  WARREN, Bridget, A. ,  DUGGAN, Brendan, M. ,  FORSYTHE, Ian, J. ,  LEE, Ernestine, A. ,  HAFALIA, April, J.A. ,  RAMKUMAR, Jayalaxmi ,  CHAWLA, Narinder, K. ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  GORVAD, Anne, E. ,  TRAN, Uyen, K. ,  LI, Joana, X. ,  YAO, Monique, G. ,  ISON, Craig, H. ,  GRIFFIN, Jennifer, A. ,  CHANG, Hsin-Ru ,  EMERLING, Brooke, M. ,  TANG, Y. Tom ,  LAL, Preeti G. ,  KABLE, Amy E. ,  MARQUIS, Joseph P. ,  JIANG, Xin ,  JACKSON, Alan A. ,  ZEBARJADIAN, Yeganeh ,  SWARNAKAR, Anita ,  WILSON, Amy D. ,  JIN, Pei ,  RICHARDSON, Thomas W. ,  BHATIA, Umesh ,  BURRILL, John C. ,  LEE, Sally ,  BLAKE, Julie J. ,  HO, Anne ,  ZHENG, Wenjin ,  GAO, Jing ,  LEE, Soo Yeun

IPC分类号： C12N9/00 ,  C12N9/14 ,  C12N9/16 ,  C07K16/00 ,  C07K1/00

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C12N9/20

摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.

公开(公告)号：EP1387888A2

公开(公告)日：2004-02-11

申请号：EP01992356.4

申请日：2001-12-19

申请人： Incyte Genomics, Inc.

发明人： BAUGHIN, Mariah, R. ,  LU, Yan ,  ARVIZU, Chandra S. ,  RAMKUMAR, Jayalaxmi ,  YAO, Monique, G. ,  POLICKY, Jennifer, L. ,  CHAWLA, Narinder, K. ,  TRIBOULEY, Katherine, M. ,  YUE, Henry ,  BATRA, Sjeev ,  DING, Li ,  LAL, Preeti, G. ,  BOROWSKY, Mark, L. ,  LU, Dyung, Aina, M. ,  GANDHI, Ameena, R. ,  GRIFFIN, Jennifer, A. ,  XU, Yuming ,  AZIMZAI, Yalda ,  GIETZEN, Kimberly, J. ,  TANG, Y. Tom ,  WARREN, Bridget A. ,  MASON, Patricia M. ,  BURFORD, Neil ,  HAFALIA, April J.A. ,  LEE, Ernestine A. ,  YANG, Junming ,  GORVAD, Ann E. ,  EMERLING, Brooke M. ,  MARQUIS, Joseph P. ,  LEE, Soo Yeun ,  SWARNAKAR, Anita ,  REDDY, Roopa ,  JIANG, Xin ,  JACKSON, Alan, A.

IPC分类号： C12N15/12 ,  C07K14/47 ,  A01K67/027 ,  C12N5/10 ,  C07K16/18 ,  C12Q1/68 ,  G01N33/68

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  G01N33/6875 ,  G01N2500/00 ,  Y02A50/55 ,  Y02A50/58

摘要： The invention provides human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. The invention also provides expression vectors. host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.