公开(公告)号：EP3623480A1

公开(公告)日：2020-03-18

申请号：EP18799253.2

申请日：2018-05-11

申请人： Industry-Academic Cooperation Foundation Gyeongsang National University

发明人： KIM, Seon Won ,  HAN, Hyo Jung ,  KIM, Sin Young ,  PARK, Ji Bin

IPC分类号： C12Q1/04 ,  C12Q1/26 ,  C12Q1/533 ,  C12P1/00

摘要： The present invention provides a marker composition for selecting a living modified organism, which allows transformation and the production of a target product without antibiotics or antibiotic resistance genes, a living modified organism, a method of transforming an organism, and a method of producing a target product. The present invention provides a marker composition for selecting a living modified organism, which may basically prevent problems caused by the use of antibiotics and antibiotic resistance genes and produce a target product at a high yield, a living modified organism, a method of transforming an organism, and a method of producing a target product.

公开(公告)号：EP4431615A1

公开(公告)日：2024-09-18

申请号：EP22893110.1

申请日：2022-11-03

申请人： Industry-Academic Cooperation Foundation Gyeongsang National University

发明人： KIM, Seon Won ,  PARK, Ji Bin ,  JEONG, Seong Hee ,  KWON, Moon Hyuk

IPC分类号： C12P23/00 ,  C12N9/02 ,  C07K14/245 ,  C12N15/70 ,  C12N9/12 ,  C12N9/10

CPC分类号： C12N9/90 ,  C12P23/00 ,  C12N9/0004 ,  C07K14/245 ,  C12N9/10 ,  C12N15/70 ,  C12N9/12

摘要： The present invention relates to a composition for preparing retinoid, and more specifically, the composition comprises: a NADH or NADPH, a Beta-Carotene Oxygenase and a flavodoxin or a ferredoxin or a reductase of flavodoxin or ferredoxin; or a microorganism expressing them; or a culture or pulverized product of the microorganism, and thus can expand the supply metabolism of reducing electrons to enhance retinoid productivity through an increase in the activity of the cytochrome P450 system and provide a foundation for the low-cost production of raw materials, and thereby enhance the economic feasibility and efficiency of retinoid production.