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公开(公告)号：EP3292398A1
公开(公告)日：2018-03-14
申请号：EP16720530.1
申请日：2016-04-28
IPC分类号： G01N27/327 , C12Q1/00
CPC分类号： G01N27/3272 , C12Q1/004 , C12Q1/26 , C12Q1/32 , G01N27/3271 , G01N2035/00118
摘要： An electrochemical test device for use in determining a concentration of each of a first analyte and a second analyte in a fluid sample is provided. The electrochemical test device comprises a set of electrodes including a first working electrode having sensing chemistry for the first analyte and a second working electrode having sensing chemistry for the second analyte, wherein the first analyte is lactate and the sensing chemistry for the lactate comprises lactate oxidase and an electron transfer agent, and wherein the sensing chemistry for the second analyte comprises a diaphorase, an electron transfer agent, an NAD(P)+-dependent dehydrogenase and a cofactor for the NAD(P)+-dependent dehydrogenase.
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公开(公告)号：EP3289344A1
公开(公告)日：2018-03-07
申请号：EP16720528.5
申请日：2016-04-28
IPC分类号： G01N27/327 , C12Q1/00
CPC分类号： G01N15/0656 , C12Q1/005 , C12Q1/006 , G01N27/327 , G01N27/3272
摘要： An electrochemical test device for determining a concentration of one or more analytes in a fluid sample is provided. The electrochemical test device comprises a set of electrodes including two or more working electrodes, each working electrode for determining the concentration of a corresponding analyte, and sensing chemistry for each working electrode, wherein the sensing chemistry for a first of the two or more working electrodes comprises a diaphorase, an electron transfer agent, an NAD(P)+-dependent dehydrogenase and a cofactor for the NAD(P)+-dependent dehydrogenase, wherein at least some of the diaphorase for the first working electrode is disposed in a diaphorase-containing layer which extends over the first working electrode and at least a second of the two or more working electrodes.
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公开(公告)号：EP3289343A1
公开(公告)日：2018-03-07
申请号：EP16720526.9
申请日：2016-04-28
IPC分类号： G01N27/327 , C12Q1/00
CPC分类号： G01N27/3272 , C12Q1/004 , C12Q1/32 , G01N27/3273
摘要： An electrochemical test device for determining a concentration of an analyte in a fluid sample is provided. The electrochemical test device comprises a set of electrodes including a working electrode for the analyte and sensing chemistry for the working electrode, wherein the sensing chemistry comprises a diaphorase, an electron transfer agent having a standard redox potential in the range of −0.52 to 0.18 V, an NAD(P)+-dependent dehydrogenase and a cofactor for the NAD(P)+-dependent dehydrogenase.
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公开(公告)号：EP3213060A1
公开(公告)日：2017-09-06
申请号：EP15790221.4
申请日：2015-10-29
发明人： CARDOSI, Marco , BLYTHE, Stephen
IPC分类号： G01N27/327
CPC分类号： G01N27/3274 , A61B5/1451 , A61B5/14517 , A61B5/1477 , A61B5/157 , A61B10/0051 , A61B10/0064 , A61B10/007 , A61B2010/0067 , A61B2010/008 , A61B2010/0087 , A61B2562/0295 , C12Q1/001 , C12Q1/006 , G01N27/301 , G01N33/48707
摘要： A method of using an electrochemical device includes at least first and second electrodes; a chamber for receiving a fluid sample and defining a volume partially bounded by a first portion of the first electrode and a second portion of the second electrode, the first portion having a first characteristic for influencing an electrochemical reaction at the first portion, the second portion having a second characteristic for influencing an electrochemical reaction at the second portion, the first and second characteristics having a predetermined relationship. The method also includes receiving a fluid sample in the chamber; measuring first and second electrical outputs at least one of the first and second electrodes; and determining whether the first and second electrical outputs are related according to the predetermined relationship.
摘要翻译： 一种使用电化学装置的方法，包括：至少第一和第二电极; 腔室，用于接收流体样品并限定由第一电极的第一部分和第二电极的第二部分部分地界定的体积，第一部分具有用于影响第一部分处的电化学反应的第一特性，第二部分 具有用于影响所述第二部分处的电化学反应的第二特性，所述第一特性和所述第二特性具有预定关系，并且其中所述方法包括：在所述室中接收流体样本; 在所述第一和第二电极中的至少一个中测量第一和第二电输出; 以及根据预定关系确定第一和第二电输出是否相关。
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公开(公告)号：EP3292397A1
公开(公告)日：2018-03-14
申请号：EP16720525.1
申请日：2016-04-28
IPC分类号： G01N27/327 , C12Q1/00 , C07F15/00
CPC分类号： C12Q1/004 , A61B5/14532 , C07F15/0053 , C12Q1/006 , G01N27/3272 , G01N2333/904
摘要： A composition is provided. The composition comprises an enzyme and a ruthenium- or osmium-based electron transfer agent, wherein the ruthenium- or osmium-based electron transfer agent is a complex [M(A)x(B)y] (X)n wherein M is ruthenium or osmium; A is an amine ligand; each B is a ligand different to A; x is an integer selected from 1 to 5; y is an integer selected from 1 to 5; x+y is 6 or 8; n is an integer selected from 1 to 6; and X is any suitable counterion.
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公开(公告)号：EP3289345A1
公开(公告)日：2018-03-07
申请号：EP16720529.3
申请日：2016-04-28
IPC分类号： G01N27/327 , C12Q1/00
CPC分类号： G01N27/327 , C12Q1/004 , C12Q1/006 , C12Q1/32 , G01N27/3272
摘要： An electrochemical test device for determining a concentration of an analyte in a fluid sample is provided. The electrochemical test device comprises a set of electrodes including a working electrode for the analyte and sensing chemistry for the working electrode, wherein the sensing chemistry is disposed on the working electrode in at least one layer, each layer comprising a diaphorase, an electron transfer agent having a standard redox potential in the range of −0.52 to 0.18 V, an NAD(P)+-dependent dehydrogenase and a cofactor for the NAD(P)+-dependent dehydrogenase.
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公开(公告)号：EP3234568A1
公开(公告)日：2017-10-25
申请号：EP15816846.8
申请日：2015-12-18
IPC分类号： G01N27/327
CPC分类号： G01N27/3272
摘要： An electrochemical test device for determining a concentration of an analyte in a fluid sample, the electrochemical test device comprising: a support layer; a conductor layer above the support layer, the conductor layer comprising a set of electrodes; a spacer layer above the conductor layer, the spacer layer defining a sample introduction channel for introducing the fluid sample to the set of electrodes; and a cover above the spacer layer for covering the top of the sample introduction channel; wherein the electrochemical test device comprises an air passageway for venting air from the sample introduction channel, and wherein the air passageway is formed below the spacer layer.
摘要翻译： 一种用于确定流体样品中分析物浓度的电化学测试装置，该电化学测试装置包括：支撑层; 在所述支撑层上方的导体层，所述导体层包括一组电极; 在所述导体层上方的间隔层，所述间隔层限定用于将所述流体样本引入到所述电极组的样本引入通道; 以及位于所述间隔层上方的盖，用于覆盖所述样本引入通道的顶部; 其中所述电化学测试装置包括用于从所述样品引入通道排出空气的空气通道，并且其中所述空气通道形成在所述间隔层下方。
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