专利检索 ap:("Instytut Chemii Bioorganicznej PAN") AND inv:"KURZYNSKA-KOKORNIAK, Anna" 第 1 页

1.

发明授权
PEPTIDE WITH THE ENZYMATIC ACTIVITY OF A DICER-LIKE PROTEIN, A METHOD FOR PREPARING SHORT RNA MOLECULES, AND USE THEREOF 有权
标题翻译：具有类似蛋白质的蛋白质的酶活性的肽，制备短RNA分子的方法及其用途

公开(公告)号：EP2726619B1

公开(公告)日：2017-12-20

申请号：EP12738654.8

申请日：2012-06-25

申请人： Instytut Chemii Bioorganicznej PAN

发明人： FIGLEROWICZ, Marek , TWORAK, Aleksander , PODKOWINSKI, Jan , KORALEWSKA, Natalia , KURZYNSKA-KOKORNIAK, Anna

IPC分类号： C12N15/82

CPC分类号： C12N9/22 , C12N15/8218 , C12P19/34

2.

发明公开
AN RNA OLIGOMER, METHODS FOR REGULATING A MICRORNA PRODUCTION PROCESS AND RNA OLIGOMERS USED AS MICRORNA PRODUCTION PROCESS REGULATORS 审中-公开
标题翻译： RNA低聚物的方法用于控制的微小RNA的生产工艺和作为使用RNA低聚物的microRNA调节器的方法

公开(公告)号：EP2817408A1

公开(公告)日：2014-12-31

申请号：EP13711481.5

申请日：2013-02-20

申请人： Instytut Chemii Bioorganicznej PAN

发明人： KURZYNSKA-KOKORNIAK, Anna , KORALEWSKA, Natalia , FIGLEROWICZ, Marek , TYCZEWSKA, Agata , TWARDOWSKI, Tomasz

IPC分类号： C12N15/115

CPC分类号： C12N15/115 , C12N2310/16

摘要： The present invention relates to an RNA oligomer, methods for regulating ' a miRNA production process and RNA oligomers used as miRNA production process regulators. More precisely, the present invention relates to use of RNA oligomers disrupting a pre-miRNA structure as miRNA production process regulators. Oligomer interactions with a miRNA precursor (pre-miRNA) change the precursor' s secondary and tertiary structure. In consequence, the pre-miRNA is not specifically recognised and cleaved by the Dicer ribonuclease, and the specific miRNA is not produced.

3.

发明公开
PEPTIDE WITH THE ENZYMATIC ACTIVITY OF A DICER-LIKE PROTEIN, A METHOD FOR PREPARING SHORT RNA MOLECULES, AND USE THEREOF 有权
标题翻译： WITH A Dicer酶蛋白的酶活性肽，用于生产短链RNA分子及其用途

公开(公告)号：EP2726619A1

公开(公告)日：2014-05-07

申请号：EP12738654.8

申请日：2012-06-25

申请人： Instytut Chemii Bioorganicznej PAN

发明人： FIGLEROWICZ, Marek , TWORAK, Aleksander , PODKOWINSKI, Jan , KORALEWSKA, Natalia , KURZYNSKA-KOKORNIAK, Anna

IPC分类号： C12N15/82

CPC分类号： C12N9/22 , C12N15/8218 , C12P19/34

摘要： The subject of the invention is a peptide with the enzymatic activity of a Dicer-like protein, a method for preparing short RNA molecules, and use thereof. The purpose of the solution was to develop a new method of producing short RNA molecules, using a new, MtDCLlpepA peptide of a Dicer protein activity designed by inventors.

摘要翻译： 在本发明的主题是具有切酶 - 样蛋白，用于制备短RNA分子的方法的酶活性的肽，以及它们的使用。溶液什么开发生产短RNA分子，使用由发明人设计了一种切酶蛋白活性的一种新的，MtDCL1pepA肽的新方法的目的。