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公开(公告)号:EP1824514B1
公开(公告)日:2015-03-04
申请号:EP05852564.3
申请日:2005-11-30
发明人: CARTON, Jill , CUNNINGHAM, Mark , DAS, Anuk , DUFFY, Karen , KNIGHT, David, M. , LAMB, Roberta , MBOW, Mouhamadou, L. , RAGHUNATHAN, Gopalan , SAN MATEO, Lani , SARISKY, Robert, T. , STOWELL, Nicole , SWEET, Raymond , ZHAO, Shanrong , CHEN, Shizhong , GILES-KOMAR, Jill , PICHA, Kristen , STOJANOVIC-SUSULIC, Vedrana , GOLETZ, Theresa, J.
IPC分类号: A61K39/42 , A61K39/395 , A61K38/16 , C07K14/52 , C07K14/705 , C07K16/28 , A61P37/00 , A61P31/00
CPC分类号: C07K16/2896 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
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公开(公告)号:EP2344175B1
公开(公告)日:2015-07-22
申请号:EP09818568.9
申请日:2009-10-02
IPC分类号: A61K38/17
CPC分类号: C07K16/2896 , A61K38/177 , A61K2039/505
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公开(公告)号:EP2350304B1
公开(公告)日:2016-12-14
申请号:EP09824182.1
申请日:2009-10-30
发明人: CUNNINGHAM, Mark , SAN MATEO, Lani , SARISKY, Robert, T. , SWEET, Raymond , RAUCHENBERGER, Robert , RUTZ, Mark , FENG, Yiqing , HEERINGA, Katharine , LUO, Jinquan , TENG, Fang , TEPLYAKOV, Alexey , WU, Sheng-jiun
IPC分类号: C12P21/06 , C07K16/28 , A61K39/395
CPC分类号: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
摘要: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
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公开(公告)号:EP1945820B1
公开(公告)日:2013-08-28
申请号:EP06846174.8
申请日:2006-10-26
发明人: DUFFY, Karen, E. , HUANG, Chong, C. , LAMB, Roberta , MBOW, Mouhamadou, L. , SARISKY, Robert, T. , SAN, Mateo, Lani
IPC分类号: C07K16/28
CPC分类号: C07K16/2896 , A61K2039/505 , C07K2317/56 , C07K2317/567 , C07K2317/75
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公开(公告)号:EP1945657B1
公开(公告)日:2011-10-26
申请号:EP06846186.2
申请日:2006-10-30
申请人: Janssen Biotech, Inc
IPC分类号: C07K14/00
CPC分类号: C07K14/705 , A61K38/00 , A61K48/00
摘要: TLR3 glycosylation site muteins, nucleic acids encoding the muteins, and methods of modulating TLR3 activity in a cell are disclosed.
摘要翻译: 公开了TLR3糖基化位点突变蛋白,编码突变蛋白的核酸以及调节细胞中TLR3活性的方法。
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