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    Method for making at least partially porous implants by precision powder injection molding
    2.
    发明公开
    Method for making at least partially porous implants by precision powder injection molding 有权
    通过精密粉末注射成型制造至少部分多孔植入物的方法

    公开(公告)号：EP0988839A3

    公开(公告)日：2000-04-05

    申请号：EP99307388.1

    申请日：1999-09-17

    申请人： JOHNSON & JOHNSON PROFESSIONAL Inc.

    发明人： Matthews, Frank D. ,  Caldarise, Salvatore

    IPC分类号： A61F2/28 ,  C04B38/04 ,  C04B38/06 ,  C08J9/26 ,  C22C1/08

    CPC分类号： B22F3/225 ,  A61F2/30771 ,  A61F2/3094 ,  A61F2/30942 ,  A61F2/36 ,  A61F2002/3092 ,  A61F2002/30957 ,  A61F2002/30968 ,  B22F2998/00 ,  B29C43/006 ,  B29L2031/7532 ,  C04B38/04 ,  C04B2111/00836 ,  C04B35/00

    摘要： An implant component adapted for bone attachment or replacement is molded from a feed stock which contains a soluble major binder, a backbone binder and structural powder material. After the feed stock is injection molded to form a compact or preform, the major binder is removed from the green article, leaving a structure of interconnected porosity or texture, while the backbone binder remains until the component is sintered. Preferably, the amount of the soluble binder is set to increase the porosity, or reduce the stiffness, of the finished component, thus introducing a biocompatible or growth-enhancing level of porosity or stiffness during the molding process. In further or alternative embodiments, the component may be injection molded onto or about a solvent-leachable spacer preform and/or adjacent to another injected or molded portion of the component which serves as a structural body, frame or shell. In these cases, all or a part of the molded portion may be formed with a conventional precision powder molding feed stock to achieve a high packing density/low shrinkage frame or support for the spacer preform or additional porous molding. The invention also includes constructions wherein the component body is injection molded against or about a support core or plate to form a hybrid article. The resulting implant component is unitized by the sintering process into a single article having the desired dimensions, strength and porosity.

    摘要翻译： 适用于骨附着或替换的植入部件由含有可溶性主粘合剂，骨架粘合剂和结构粉末材料的原料模制而成。 在将原料注塑成型以形成压制品或预成型件之后，将主要粘合剂从未加工的制品中去除，留下相互连接的孔隙或结构的结构，同时留下主干粘合剂直到该部件被烧结。 优选地，可溶性粘合剂的量被设定为增加成品部件的孔隙率或降低刚度，由此在模制过程期间引入生物相容性或生长增强水平的孔隙率或硬度。 在进一步的或替代的实施例中，部件可以被注塑成型在可溶剂浸渍的间隔件预成型件上或附近，和/或与用作结构体，框架或壳体的部件的另一个注射或模制部分相邻。 在这些情况下，模制部分的全部或一部分可以用常规的精密粉末模制原料形成，以实现高填充密度/低收缩框架或支撑间隔件预制件或附加多孔模制件。 本发明还包括这样的构造，其中部件主体被注射模制在支撑芯或板周围以形成混合物品。 得到的植入物组分通过烧结过程被整合成具有所需尺寸，强度和孔隙率的单一制品。

    Method for making at least partially porous implants by precision powder injection molding
    3.
    发明公开
    Method for making at least partially porous implants by precision powder injection molding 有权
    一种用于通过精密注塑的方式产生至少部分多孔植入物的过程

    公开(公告)号：EP0988839A2

    公开(公告)日：2000-03-29

    申请号：EP99307388.1

    申请日：1999-09-17

    申请人： JOHNSON & JOHNSON PROFESSIONAL Inc.

    发明人： Matthews, Frank D. ,  Caldarise, Salvatore

    IPC分类号： A61F2/28 ,  C04B38/04 ,  C04B38/06 ,  C08J9/26 ,  C22C1/08

    CPC分类号： B22F3/225 ,  A61F2/30771 ,  A61F2/3094 ,  A61F2/30942 ,  A61F2/36 ,  A61F2002/3092 ,  A61F2002/30957 ,  A61F2002/30968 ,  B22F2998/00 ,  B29C43/006 ,  B29L2031/7532 ,  C04B38/04 ,  C04B2111/00836 ,  C04B35/00

    摘要： An implant component adapted for bone attachment or replacement is molded from a feed stock which contains a soluble major binder, a backbone binder and structural powder material. After the feed stock is injection molded to form a compact or preform, the major binder is removed from the green article, leaving a structure of interconnected porosity or texture, while the backbone binder remains until the component is sintered. Preferably, the amount of the soluble binder is set to increase the porosity, or reduce the stiffness, of the finished component, thus introducing a biocompatible or growth-enhancing level of porosity or stiffness during the molding process. In further or alternative embodiments, the component may be injection molded onto or about a solvent-leachable spacer preform and/or adjacent to another injected or molded portion of the component which serves as a structural body, frame or shell. In these cases, all or a part of the molded portion may be formed with a conventional precision powder molding feed stock to achieve a high packing density/low shrinkage frame or support for the spacer preform or additional porous molding. The invention also includes constructions wherein the component body is injection molded against or about a support core or plate to form a hybrid article. The resulting implant component is unitized by the sintering process into a single article having the desired dimensions, strength and porosity.

    摘要翻译： 对于骨连接或更换植入部件angepasst由包含可溶性主要粘合剂，骨干粘合剂和结构粉末材料的原料模制而成。 该原料被注射成型为形成紧凑的或预型体后，将主要粘合剂从生坯物品移除，留下互连孔隙或纹理的结构，而主链粘合剂保持，直到该部件进行烧结。 优选地，将可溶性粘合剂的量被设定为提高孔隙率，或降低硬度，成品部件的，在模塑过程中从而使引进的孔隙率或刚度的生物相容或生长增强水平。 在其它或替代实施例中，部件可以被注射到溶剂浸出的间隔模制预成型坯或约和/或邻近于另一注射或模制用作结构体，框架或壳组件的部分。 在本文情况下，所有或模制部的一部分可以与常规的精密粉末成型的原料形成，以实现用于间隔预型体或额外的多孔成型填充密度高/低收缩框架或支撑。 因此本发明包括构造worin构件体被注射成型对或约支承芯或板以形成混合制品。 将得到的植入物组件，通过在烧结过程单元化具有所需尺寸，强度和孔隙率的单个制品。

    Joint prosthesis augmentation system
    4.
    发明公开
    Joint prosthesis augmentation system 失效
    Gelenkprothesenerhöhungssystem

    公开(公告)号：EP0781533A1

    公开(公告)日：1997-07-02

    申请号：EP96308585.7

    申请日：1996-11-27

    申请人： JOHNSON & JOHNSON PROFESSIONAL Inc.

    发明人： Matthews, Frank D. ,  Brown, Robert S. ,  Cicierega, Gerald J. ,  Hurlburt, Robert ,  O'Neil, Michael J.

    IPC分类号： A61F2/30 ,  A61F2/38

    CPC分类号： A61F2/30734 ,  A61F2/3859 ,  A61F2002/30143 ,  A61F2002/30158 ,  A61F2002/30187 ,  A61F2002/30405 ,  A61F2002/30436 ,  A61F2002/30484 ,  A61F2002/30507 ,  A61F2002/3052 ,  A61F2002/30594 ,  A61F2002/30736 ,  A61F2002/30772 ,  A61F2002/30774 ,  A61F2002/30795 ,  A61F2002/30904 ,  A61F2220/0025 ,  A61F2220/0041 ,  A61F2230/0017 ,  A61F2230/0026 ,  A61F2230/0034 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00179

    摘要： An augmentation system for an implantable bone prosthesis, such as a femoral component of a knee joint prosthesis, includes an augmenting block (12) having an aperture (14) disposed therein. A collet (16) having an expandable distal end (16), extending beyond one surface of the augmenting block, is positioned within the aperture. The proximal end of the collet includes a cavity (17) that receives an expansion pin (20) that is adapted to communicate with the collet to expand the collet. The distal end of the collet is adapted to fit within a mounting cavity (35) of a joint prosthesis. With the augmenting block placed on the appropriate surface of the joint prosthesis, the distal end of the collet is positioned within the mounting cavity. Advancement of the expansion pin causes the distal end of the collet to expand, thus frictionally and/or mechanically engaging the interior walls of the mounting cavity to firmly secure the augmenting system to the prosthesis. The expansion pin can include threads which mate with corresponding threads within the cavity of the collet. Alternatively, the pin and collet cavity can include ratchet and pawl-like surface features.

    摘要翻译： 用于可植入骨假体（例如膝关节假体的股骨部件）的增强系统包括其中设置有孔（14）的增强块（12）。 具有延伸超过增强块的一个表面的可扩展远端（16）的夹头（16）定位在孔内。 夹头的近端包括容纳膨胀销（20）的空腔（17），所述膨胀销适于与夹头连通以膨胀夹头。 夹头的远端适于装配在关节假体的安装腔（35）内。 当增加块放置在关节假体的适当表面上时，夹头的远端位于安装腔内。 膨胀销的推进使得夹头的远端膨胀，从而摩擦和/或机械接合安装腔的内壁，以将增强系统牢固地固定在假体上。 膨胀销可以包括与夹头的空腔内的相应螺纹配合的螺纹。 或者，销和夹头腔可以包括棘轮和棘爪状表面特征。