公开(公告)号：EP3964525A2

公开(公告)日：2022-03-09

申请号：EP20794288.9

申请日：2020-04-23

申请人： Joint Stock Company "Biocad"

发明人： ULITIN, Andrei Borisovich ,  KOZLOVA, Olesya Nikolaevna ,  GORDEEV, Aleksandr Andreevich ,  BURNYSHEVA, Ksenia Mihailovna ,  ISHUTINOVA, Anastasia Nikolaevna ,  SOZONOVA, Aleksandra Aleksandrovna ,  AGEEV, Sergei Andreevich ,  DORONIN, Aleksandr Nikolaevich ,  TSYMPILOV, Vladimir Sergeevich ,  MITROSHIN, Ivan Vladimirovich ,  SOLOVYEV, Valery Vladimirovich ,  USTIUGOV, Iakov Iurevich ,  IVANOV, Roman Alekseevich ,  MOROZOV, Dmitry Valentinovich

IPC分类号： C07K16/24 ,  C07K16/28 ,  C12N5/10 ,  C12N15/13 ,  C12N15/63 ,  C12P21/08 ,  A61K39/395 ,  A61P35/00

摘要： The present invention relates to biotechnology, in particular to antibodies or antigen-binding fragments thereof, and to use thereof. More particularly, the present invention relates to monoclonal antibodies that specifically bind to GITR. The invention also relates to a nucleic acid encoding said antibody or antigen-binding fragment thereof, an expression vector, a method for preparing said antibody, and use of said antibody in treatment of diseases or disorders associated with GITR.

公开(公告)号：EP4367252A2

公开(公告)日：2024-05-15

申请号：EP22838112.5

申请日：2022-07-04

申请人： Joint Stock Company "Biocad"

发明人： FEDORENKO, Lina Igorevna ,  LOMKOVA, Ekaterina Aleksandrovna ,  IAKOVLEV, Aleksandr Olegovich ,  SOZONOVA, Aleksandra Aleksandrovna ,  DVORIANKINA, Marina Konstantinovna ,  MOROZOV, Dmitry Valentinovich

IPC分类号： C12N15/86 ,  C12N7/00 ,  A61K35/76 ,  A61K9/08 ,  A61K9/19 ,  A61K47/18 ,  A61K47/26 ,  A61K47/34 ,  A61K47/40 ,  A61K47/02

CPC分类号： Y02A50/30 ,  A61K9/08 ,  A61K9/19 ,  A61K35/76 ,  A61K47/40 ,  C12N15/86 ,  C12N2750/1414320130101 ,  C12N2750/1415120130101

公开(公告)号：EP3693388A1

公开(公告)日：2020-08-12

申请号：EP18864122.9

申请日：2018-10-02

申请人： Closed Joint Stock Company "Biocad"

发明人： SOFRONOVA, Ekaterina Vladimirovna ,  MISORIN, Aleksei Konstantinovich ,  DORONIN, Aleksandr Nikolaevich ,  NEMANKIN, Timofey Aleksandrovich ,  SOZONOVA, Aleksandra Aleksandrovna ,  ZHIRIVSKAIA, Galina Stepanovna ,  LEGOTSKY, Sergey Aleksandrovich ,  VLADIMIROVA, Anna Konstantinovna ,  BELIASNIKOVA, Alina Valerevna ,  SHCHEMELEVA, Mariia Aleksandrovna ,  IAKOVLEV, Pavel Andreevich ,  SOLOVYEV, Valery Vladimirovich ,  KRENDELEVA, Elena Andreevna ,  PESTOVA, Natalia Evgenevna ,  MOROZOV, Dmitry Valentinovich

IPC分类号： C07K16/24 ,  C12N15/63 ,  A61K39/00 ,  A61P11/06

摘要： The present invention relates to biotechnology and provides antibodies that specifically bind to IL-5Rα. The invention also relates to DNA encoding said antibodies, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibodies.