公开(公告)号：EP1877394A1

公开(公告)日：2008-01-16

申请号：EP06728421.6

申请日：2006-04-04

申请人： Jubilant Organosys Limited

发明人： DAS, Prasenjit Prafulla ,  GOANKAR, Santosh Laxman ,  MANJUNATHA, Sulur, G. ,  NARAHARI BABU, Ambati

IPC分类号： C07D307/87

CPC分类号： C07D307/87

摘要： The present invention relates to Formula (I), a process for the preparation of highly pure Escitalopram or its acid addition salts which comprises: a) reacting racemic diol or its ester derivative (III) with an optically active acid and at least one solvent to get enantiomerically pure diastereomer (IIIA); b) separating the enantiomerically pure diastereomer (IIIA) from its optically active acid salt by treating it with base and followed by stereo selective cyclization; c) separating the Escitalopram base.

公开(公告)号：EP1670797A1

公开(公告)日：2006-06-21

申请号：EP04787585.1

申请日：2004-09-24

申请人： Jubilant Organosys Limited

发明人： SRINIVASA RAO, Guntu ,  PRASANNA KUMAR, Basavapatna, N. ,  MANJUNATHA, Sulur, G. ,  KULKARNI, Ashok, Krishna

IPC分类号： C07D471/04

CPC分类号： C07D471/04

摘要： A process is provided for the preparation of risperidone of Formula (1); which process comprises reacting, in a condensation reaction, 6-fluoro-3-(4- piperidinyl)-1,2-benzisoxazole monohydrochloride of Formula (2) with 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2,a]pyrimidin-4-one monohydrochloride of Formula (3).