专利检索 ap:("Jubilant Organosys Limited") AND inv:"NARAHARI BABU, Ambati" 第 1 页

1.

发明公开
PROCESS FOR THE PREPARATION OF ESCITALOPRAM OR ITS ACID ADDITION SALTS 审中-公开
标题翻译：用于生产依他普仑或其及其酸加成盐

公开(公告)号：EP1877394A1

公开(公告)日：2008-01-16

申请号：EP06728421.6

申请日：2006-04-04

申请人： Jubilant Organosys Limited

发明人： DAS, Prasenjit Prafulla , GOANKAR, Santosh Laxman , MANJUNATHA, Sulur, G. , NARAHARI BABU, Ambati

IPC分类号： C07D307/87

CPC分类号： C07D307/87

摘要： The present invention relates to Formula (I), a process for the preparation of highly pure Escitalopram or its acid addition salts which comprises: a) reacting racemic diol or its ester derivative (III) with an optically active acid and at least one solvent to get enantiomerically pure diastereomer (IIIA); b) separating the enantiomerically pure diastereomer (IIIA) from its optically active acid salt by treating it with base and followed by stereo selective cyclization; c) separating the Escitalopram base.