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    A SYSTEM FOR THERMAL ABLATION TREATMENT PLANNING
    2.
    发明公开
    A SYSTEM FOR THERMAL ABLATION TREATMENT PLANNING 审中-公开

    公开(公告)号：EP4245241A1

    公开(公告)日：2023-09-20

    申请号：EP22161937.2

    申请日：2022-03-14

    申请人： Koninklijke Philips N.V.

    发明人： ISOLA, Alfonso Agatino ,  CIANCARELLA, Martina ,  HAUTVAST, Guillaume Leopold Theodorus Frederik ,  STROOSMA, Otto

    IPC分类号： A61B34/10 ,  A61B18/14

    摘要： A system (100) for thermal ablation treatment planning is provided that allows to provide an entry condition (21a, 21b; 22a, 22b) indicative of how a trajectory of a thermal ablation source (50) is to enter a treatment region (60). A configuration space is then provided that comprises, as configurations, a) candidate positions corresponding to candidate trajectories (311a, 311b; 312a, 312b) entering the treatment region in accordance with the provided entry condition, and b) candidate thermal control parameter values (32i, 32ii) for each of the candidate positions. Based on candidate thermal impacts (10a, 10b, 10c, 10d) provided for each of the configurations, a treatment plan is determined that satisfies a thermal impact objective.

    RADIATION THERAPY PLANNING
    7.
    发明公开
    RADIATION THERAPY PLANNING 审中-公开

    公开(公告)号：EP4015038A1

    公开(公告)日：2022-06-22

    申请号：EP20215273.2

    申请日：2020-12-18

    申请人： Koninklijke Philips N.V.

    发明人： WEESE, Juergen ,  ISOLA, Alfonso Agatino ,  BONDAR, Maria Luiza ,  VIK, Torbjoern ,  FLAESCHNER, Nick ,  WIEGERT, Jens ,  HEESE, Harald Sepp

    IPC分类号： A61N5/10

    摘要： The invention relates a system for assisting in planning a radiation therapy treatment provided using a treatment plan comprising irradiation parameters for controlling a delivery of radiation. The system is configured to (i) receive a first dose distribution, (ii) obtain a first objective function, which depends upon at least one parameter and a dose distribution, (iii) determine a first value of the parameter such that the first objective function fulfills a predefined criterion when being evaluated for the first value of the parameter and for a second dose distribution derived from the first dose distribution, (iii) provide the first objective function in connection with the first value of the at least one parameter to a user for modifying the first objective function to generate a second objective function, and (v) determine the treatment plan using the second objective function. Further, the invention relates to a corresponding method and computer program.

    ROBUSTNESS EVALUATION OF BRACHYTHERAPY TREATMENT PLAN
    9.
    发明公开
    ROBUSTNESS EVALUATION OF BRACHYTHERAPY TREATMENT PLAN 审中-公开

    公开(公告)号：EP3466487A1

    公开(公告)日：2019-04-10

    申请号：EP17194553.8

    申请日：2017-10-03

    申请人： Koninklijke Philips N.V.

    发明人： ISOLA, Alfonso Agatino ,  NEUKIRCHEN, Christoph ,  HAUTVAST, Guillaume Leopold Theodorus Frederik ,  SENDEN, Dave

    IPC分类号： A61N5/10

    摘要： The invention relates to a system and a method for assisting in planning a radiation therapy treatment, the treatment being delivered on the basis of a treatment plan including error-prone parameter values of first treatment parameters. In the system, a robustness evaluation unit (10) obtains planned parameter values of the first treatment parameters, generates perturbed parameter configurations including perturbed values of the first treatment parameters, the perturbed parameter values deviating from the planned parameter values by possible error values of the first treatment parameters occurring during the treatment, and estimates for each perturbed parameter configuration a radiation dose distribution resulting from a treatment delivered on the basis of the perturbed parameter configuration and/or determines the treatment plan on the basis of the perturbed parameter configurations.

    WARM START INITIALIZATION FOR EXTERNAL BEAM RADIOTHERAPY PLAN OPTIMIZATION
    10.
    发明公开
    WARM START INITIALIZATION FOR EXTERNAL BEAM RADIOTHERAPY PLAN OPTIMIZATION 审中-公开

    公开(公告)号：EP3357539A1

    公开(公告)日：2018-08-08

    申请号：EP17154324.2

    申请日：2017-02-02

    申请人： Koninklijke Philips N.V.

    发明人： ISOLA, Alfonso Agatino ,  NEUKIRCHEN, Christoph ,  VIK, Orbjoern ,  HEESE, Harald Sepp ,  WEESE, Juergen

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1031 ,  A61N5/1036 ,  A61N5/1047

    摘要： The invention relates to a dynamic sliding-window-like initialization for, for example, iterative VMAT algorithms. Specifically, a dynamic sliding window conversion method is contemplated where typical dynamic VMAT constraints are taken into account to find an optimal set of suitable openings (i.e. binary masks) that can be used as quasi-feasible start initialization for any VMAT algorithm that can refine until a deliverable plan is reached. Here, a multileaf leaf tip trajectory least square constrained optimization is performed to find a set of optimal unidirectional trajectories for all MLC leaf pairs of all arc points. To ensure that a quasi-feasible (or better quasi-deliverable) solution is returned, for example, a maximum dose rate, a maximum gantry speed, a maximum leafs speed, and a maximum treatment time may be enforced.