公开(公告)号：EP2837335A1

公开(公告)日：2015-02-18

申请号：EP13768225.8

申请日：2013-03-26

申请人： Kyoto Prefectural Public University Corporation

发明人： TAKAMATSU, Tetsuro ,  MINAMIKAWA, Takeo ,  HARADA, Yoshinori

IPC分类号： A61B10/00 ,  G01N21/65 ,  G01N33/48

CPC分类号： A61B5/0075 ,  A61B5/40 ,  A61B5/742 ,  G01N21/65

摘要： The present invention provides a method of detecting nerves, including: step 1 of irradiating a sample with excitation light; step 2 of detecting Raman scattering light from the sample; step 3 of calculating an intensity ratio of a wave number within a specific range of the Raman scattering light detected in the step 2 or extracting a feature of the intensity ratio and subj ecting the feature to multivariate analysis and/or statistical analysis; and step 4 of specifically displaying nerves containing unmyelinated nerves, using as an index the intensity ratio or a result from the multivariate analysis and/or the statistical analysis.

摘要翻译： 本发明提供一种检测神经的方法，包括：用激发光照射样品的步骤1; 检测来自样品的拉曼散射光的步骤2; 计算在步骤2中检测到的拉曼散射光的特定范围内的波数的强度比，或者提取强度比的特征并将特征偏离为多变量分析和/或统计分析的步骤3; 以及使用多变量分析和/或统计分析的强度比或结果作为指标来特异性显示含有无髓神经的神经的步骤4。