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    Devices and methods for extracting bodily fluids
    1.
    发明公开
    Devices and methods for extracting bodily fluids 有权
    Gerätezur Entnahme vonKörperflüssigkeiten

    公开(公告)号：EP1566146A1

    公开(公告)日：2005-08-24

    申请号：EP05250950.2

    申请日：2005-02-18

    申请人： LIFESCAN, INC.

    发明人： Hilgers, Michael Edward ,  McAllister, Devin V. ,  Menendez, Adolfo Jr

    IPC分类号： A61B10/00

    CPC分类号： A61B10/0045 ,  A61B2010/008

    摘要： A bodily fluid extraction device includes a penetration member configured for penetrating a target site and subsequently residing within the target site and extracting a bodily fluid sample. The penetration member includes a proximal end adapted for fluid communication with an analyte analysis system, a distal end, and a channel extending from the distal to the proximal end. The distal end includes a sharp portion for penetrating a target site, and a flexible feature adapted for promoting bodily fluid flow into the channel by protruding into the target site after the penetration member has penetrated the target site. A method for extracting bodily fluid includes providing a bodily fluid extraction device as described immediately above. Subsequently, a target site is penetrated with the distal end of the bodily fluid extraction device's penetration member and the flexible portion of the penetration member is caused to protrude into the target site and promote bodily fluid flow into the penetration member's channel. Bodily fluid (e.g., ISF) is then extracted from the target site (e.g., a dermal tissue target site) via the channel of the bodily fluid extraction device.

    摘要翻译： 身体液体提取装置包括穿透构件，其被配置用于穿透靶部位并随后驻留在靶部位内并提取体液样品。 穿透构件包括适于与分析物分析系统，远端和从远端延伸到近端的通道的流体连通的近端。 远端包括用于穿透目标部位的尖锐部分，以及柔性特征，其适于在穿透部件已经穿透目标部位之后通过突出到目标部位中来促进体液流入通道。 一种用于提取体液的方法包括提供如上所述的体液提取装置。 随后，目标部位被渗透到体液提取装置的穿透部件的远端，使穿透部件的柔性部突出到目标部位，并促使体液流入穿透部件的通道。 然后通过体液提取装置的通道从目标部位（例如，真皮组织靶位点）提取体液（例如ISF）。

    Physiological sample collection devices and methods of using the same
    3.
    发明公开
    Physiological sample collection devices and methods of using the same 审中-公开
    生理样本采集装置及其使用方法

    公开(公告)号：EP1284121A2

    公开(公告)日：2003-02-19

    申请号：EP02255327.5

    申请日：2002-07-30

    申请人： Lifescan, Inc.

    发明人： Yuzhakov, Vadim V. ,  McAllister, Devin V.

    IPC分类号： A61B5/15

    CPC分类号： A61B5/14546 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150465 ,  A61B5/150984 ,  A61B5/15142 ,  A61B5/157 ,  A61B2562/0295

    摘要： Devices and methods are provided for piercing the skin and accessing and collecting physiological sample therein. The subject devices include at least one fluid pathway, wherein at least a substantial portion of the distal end of the at least one fluid pathway is open to the outside environment. One or more subject devices may be integrated into a test strip for determining the concentration of at least one analyte in the sample. Also provided are methods for using the subject devices. The devices and methods are particularly suited for collecting physiological sample and determining glucose concentrations therein and, more particularly, glucose concentrations in blood, blood fractions or interstitial fluid. Also provided are kits that include the devices for use in practicing the subject methods.

    摘要翻译： 提供用于穿刺皮肤并访问和收集其中的生理样本的装置和方法。 本发明的装置包括至少一个流体路径，其中至少一个流体路径的远端的至少大部分向外部环境开放。 一个或多个目标装置可以被集成到测试条中以确定样品中至少一种分析物的浓度。 还提供了使用主题设备的方法。 该装置和方法特别适用于收集生理样品并确定其中的葡萄糖浓度，更具体地说，适用于血液，血液部分或组织间液中的葡萄糖浓度。 还提供了包含用于实践主题方法的设备的套件。

    Physiological sample collection devices and methods of using the same
    5.
    发明公开
    Physiological sample collection devices and methods of using the same 审中-公开
    生理学Sammelvorrichtungen und -Verfahren

    公开(公告)号：EP1598011A3

    公开(公告)日：2006-03-01

    申请号：EP05076860.5

    申请日：2003-05-08

    申请人： LifeScan, Inc.

    发明人： Yushakov, Vadim ,  McAllister, Devin V. ,  Olson, Lorin ,  Leong, Koon-wah ,  Teodorczyk, Maria ,  Kiser, Ernest

    IPC分类号： A61B5/15

    CPC分类号： A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B2562/0295 ,  A61B2562/12

    摘要： Devices, systems and methods are provided for piercing the skin, accessing and collecting physiological sample therein, and measuring a characteristic, e.g. , an analyte concentration, of the sampled physiological sample. The subject devices are in the form of a test strip (2) which includes a biosensor and at least one skin-piercing element (6) which is a planar extension of a portion of the biosensor. At least one fluid pathway (108,128) resides within a portion of the biosensor and within the skin-piercing element. The skin-piercing element has a space-defining configuration therein which acts as a sample fluid pooling area (22,86) upon penetration into the skin. Systems are provided which include one or more test strip devices and a meter (40) for making analyte concentration measurements. Methods for using the devices and systems are also provided.

    摘要翻译： 提供了设备，系统和方法，用于刺穿皮肤，进入和收集生理样品，并测量取样的生理样品的特征，例如分析物浓度。 本发明装置是测试条的形式，其包括生物传感器和作为生物传感器的一部分的平面延伸的至少一个皮肤刺穿元件。 至少一个流体通道位于生物传感器的一部分内并且在皮肤刺穿元件内。 皮肤刺穿元件在其中具有空间限定构造，其在穿透到皮肤中时充当样品流体汇集区域。 提供了包括一个或多个测试条装置和用于进行分析物浓度测量的仪表的系统。 还提供了使用装置和系统的方法。

    Physiological sample collection devices and methods of using the same
    6.
    发明公开
    Physiological sample collection devices and methods of using the same 审中-公开
    生理学Sammelvorrichtungen und -Verfahren

    公开(公告)号：EP1598011A2

    公开(公告)日：2005-11-23

    申请号：EP05076860.5

    申请日：2003-05-08

    申请人： LIFESCAN, INC.

    发明人： Yuzhakov, Vadim V. ,  McAllister, Devin V. ,  Olson, Lorin ,  Leong, Koon-wah ,  Teodorczyk, Maria ,  Kiser, Ernest

    IPC分类号： A61B5/15

    CPC分类号： A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B2562/0295 ,  A61B2562/12

    摘要： Devices, systems and methods are provided for piercing the skin, accessing and collecting physiological sample therein, and measuring a characteristic, e.g. , an analyte concentration, of the sampled physiological sample. The subject devices are in the form of a test strip (2) which includes a biosensor and at least one skin-piercing element (6) which is a planar extension of a portion of the biosensor. At least one fluid pathway (108,128) resides within a portion of the biosensor and within the skin-piercing element. The skin-piercing element has a space-defining configuration therein which acts as a sample fluid pooling area (22,86) upon penetration into the skin. Systems are provided which include one or more test strip devices and a meter (40) for making analyte concentration measurements. Methods for using the devices and systems are also provided.

    摘要翻译： 提供了设备，系统和方法来刺穿皮肤，进入和收集生理样品，并测量其特性，例如， ，样品生理样品的分析物浓度。 本发明装置是测试条（2）的形式，其包括生物传感器和作为生物传感器的一部分的平面延伸的至少一个皮肤刺穿元件（6）。 至少一个流体通道（108,128）位于生物传感器的一部分内并且在皮肤刺穿元件内。 皮肤刺穿元件具有其中的空间限定构造，其在穿透到皮肤中时用作样品流体汇集区域（22,86）。 提供了包括一个或多个测试条装置和用于进行分析物浓度测量的仪表（40）的系统。 还提供了使用装置和系统的方法。