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    Strip containing a series of fluid sampling and testing devices and method of making, packaging and using it
    4.
    发明公开
    Strip containing a series of fluid sampling and testing devices and method of making, packaging and using it 有权
    条用于流体取样和测试装置的多收费的包装，以及用于制造和使用该带材的方法

    公开(公告)号：EP1360935A1

    公开(公告)日：2003-11-12

    申请号：EP03252884.6

    申请日：2003-05-08

    申请人： Lifescan, Inc.

    发明人： Olson, Lorin ,  McAllister, Devin

    IPC分类号： A61B5/15

    CPC分类号： G01N33/48764 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150213 ,  A61B5/150259 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/15111 ,  A61B5/15117 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15169 ,  A61B5/15173 ,  A61B5/15182 ,  A61B5/157 ,  G01N35/00009 ,  G06F19/00 ,  Y10T436/110833

    摘要： The present invention provides continuous strips of testers in an individually-sealed water-impermeable packaging which maintains the testers in a sterile condition until used. The subject testers include a test strip sensor integrated with a microneedle for accessing and collecting a sample of physiological fluid and for measuring a chemical characteristic, such as target analyte concentration, of the sampled fluid. The present invention further provides cassettes of the subject strips for removable engagement with a meter for individually dispensing the testers and for facilitating the analysis of the sampled fluid. Also provided by the present invention are systems which include the subject strips and cassettes and such a meter. Methods of using the strips and cassettes are also provided, along with kits for practicing the subject methods.

    摘要翻译： 本发明提供了在独立密封不透水的包装直至用其保持在无菌条件下的测试器测试的连续条带。 受试者测试仪包括用于访问和收集生理流体的样品和用于测量被采样的流体的化学特性，：如靶分析物的浓度，用微针集成的测试条传感器。 本发明还提供用于可移除地接合所述对象条的盒与用于单独分配测试人员和用于促进采样流体的分析的仪表。 因此，通过的本发明包括所述对象条带和盒和这样的计量系统提供的是。 被设置成使用带和磁带的方法，用试剂盒实施本方法一起。

    Improved micro-needles and methods of manufacture and use thereof
    5.
    发明公开
    Improved micro-needles and methods of manufacture and use thereof 审中-公开
    Verbesserte Mikronadeln und Verfahren zu deren Herstellung sowie deren Verwendung

    公开(公告)号：EP1287847A1

    公开(公告)日：2003-03-05

    申请号：EP02254617.0

    申请日：2002-07-01

    申请人： LIFESCAN, INC.

    发明人： Olson, Lorin

    IPC分类号： A61M37/00 ,  A61B5/145 ,  A61B5/15 ,  A61B5/00

    CPC分类号： A61M37/0015 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150984 ,  A61B2010/008 ,  A61M2037/003 ,  A61M2037/0053

    摘要： A micro-needle (80) is provided which is particularly useful for the minimally invasive sampling of a biological fluid and/or the minimally invasive delivery of a drug or other formulation across the skin. The micro-needle (80) has a structure having a base (70) at a proximal end and a vertex (60) at a distal end (58), and an open lumen (55) extending there through and through which fluid may be transferred. The structure defines a structural axis (65) that intersects the lumenal axis (56) defined by the open lumen (55). The point of intersection (90) between these axes is at a point below the vertex (60) of the micro-needle (80) to provide a sharp apex (60) at the distal end (58) of the micro-needle (80) and defines the general configuration of the distal end (58) of the micro-needle (80), which may be selected or customized depending on the intended use of the microneedle (80). The micro-needle (80) may be integral with a measurement device for measuring the concentration of a constituent within sampled biological fluid and/or with a fluid reservoir for containing a fluid to be delivered, and may also be used in conjunction with a remote control means. Methods of making and using the micro-needle (80) of the present invention as well as kits comprising one or more of the micro-needles (80) are also provided.

    摘要翻译： 提供了一种微针，其特别可用于生物流体的微创取样和/或药物或其它制剂穿过皮肤的微创输送。 微针具有在近端具有基部和在远端具有顶点的结构，以及在其上延伸并且流体可以被传送的开放腔。 该结构限定了与由开口腔限定的内腔轴相交的结构轴线。 这些轴之间的交点位于微针顶点以下的点处，以在微针的远端提供尖锐的尖端，并且限定微针的远端的一般构型，其可以 根据微针的预期用途进行选择或定制。 微针可以与用于测量采样的生物流体中的组分浓度和/或用于容纳要输送的流体的流体储存器的测量装置成一体，并且还可以与遥控装置结合使用。 还提供了制造和使用本发明的微针的方法以及包括一个或多个微针的试剂盒。

    Minimal procedure analyte test system
    6.
    发明公开
    Minimal procedure analyte test system 有权
    最小程序分析物测试系统

    公开(公告)号：EP1980206A1

    公开(公告)日：2008-10-15

    申请号：EP08075676.0

    申请日：2003-05-08

    申请人： LifeScan, Inc.

    发明人： MCallister, Devin ,  Olson, Lorin ,  Sohrab, Borzu

    IPC分类号： A61B5/15

    CPC分类号： A61B5/14532 ,  A61B5/150022 ,  A61B5/15019 ,  A61B5/150198 ,  A61B5/150259 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/150435 ,  A61B5/150824 ,  A61B5/15111 ,  A61B5/15117 ,  A61B5/15153 ,  A61B5/15174 ,  A61B5/15176 ,  A61B5/1518 ,  A61B5/15182 ,  A61B5/15184 ,  A61B5/157 ,  G06F19/00

    摘要： A system employing an integrated analyte test strip including a biosensor and lancet is disclosed. The integration of lancet and the sensor elements eliminates the need to align the sensor to the biologic fluid sample after a lancet and lancing device are used in combination to pierce the skin. The system preferably includes a device comprising two body portions that slide relative to each other to both cock and fire a test strip at a target site. Meter reading and test strip disposal may be accomplished by removing the device from the target site. The device preferably employs a magazine loaded with test strips, with one strip being taken from the magazine each time the device is actuated. It preferably also includes a magazine in a cap to store spent test strips for disposal. The device may be turned on an off simply by removal and return of the cap.

    摘要翻译： 公开了采用包括生物传感器和刺血针的集成分析物测试条的系统。 刺血针和传感器元件的集成消除了在将刺血针和穿刺装置组合用于刺穿皮肤之后将传感器与生物液体样品对齐的需要。 该系统优选地包括装置，该装置包括两个相对于彼此滑动的主体部分，以便在目标部位处开启和启动测试条。 仪表读数和测试条处置可以通过从目标位置移除设备来完成。 该装置优选地采用装载有测试条的盒，每次启动装置时从盒中取出一个条。 它最好还包括一个帽子中的杂志，用于存放用过的测试条。 简单地通过取下和返回盖子可以打开设备。

    Physiological sample collection devices and methods of using the same
    8.
    发明公开
    Physiological sample collection devices and methods of using the same 审中-公开
    生理学Sammelvorrichtungen und -Verfahren

    公开(公告)号：EP1598011A3

    公开(公告)日：2006-03-01

    申请号：EP05076860.5

    申请日：2003-05-08

    申请人： LifeScan, Inc.

    发明人： Yushakov, Vadim ,  McAllister, Devin V. ,  Olson, Lorin ,  Leong, Koon-wah ,  Teodorczyk, Maria ,  Kiser, Ernest

    IPC分类号： A61B5/15

    CPC分类号： A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B2562/0295 ,  A61B2562/12

    摘要： Devices, systems and methods are provided for piercing the skin, accessing and collecting physiological sample therein, and measuring a characteristic, e.g. , an analyte concentration, of the sampled physiological sample. The subject devices are in the form of a test strip (2) which includes a biosensor and at least one skin-piercing element (6) which is a planar extension of a portion of the biosensor. At least one fluid pathway (108,128) resides within a portion of the biosensor and within the skin-piercing element. The skin-piercing element has a space-defining configuration therein which acts as a sample fluid pooling area (22,86) upon penetration into the skin. Systems are provided which include one or more test strip devices and a meter (40) for making analyte concentration measurements. Methods for using the devices and systems are also provided.

    摘要翻译： 提供了设备，系统和方法，用于刺穿皮肤，进入和收集生理样品，并测量取样的生理样品的特征，例如分析物浓度。 本发明装置是测试条的形式，其包括生物传感器和作为生物传感器的一部分的平面延伸的至少一个皮肤刺穿元件。 至少一个流体通道位于生物传感器的一部分内并且在皮肤刺穿元件内。 皮肤刺穿元件在其中具有空间限定构造，其在穿透到皮肤中时充当样品流体汇集区域。 提供了包括一个或多个测试条装置和用于进行分析物浓度测量的仪表的系统。 还提供了使用装置和系统的方法。

    Physiological sample collection devices and methods of using the same
    10.
    发明公开
    Physiological sample collection devices and methods of using the same 审中-公开
    生理学Sammelvorrichtungen und -Verfahren

    公开(公告)号：EP1598011A2

    公开(公告)日：2005-11-23

    申请号：EP05076860.5

    申请日：2003-05-08

    申请人： LIFESCAN, INC.

    发明人： Yuzhakov, Vadim V. ,  McAllister, Devin V. ,  Olson, Lorin ,  Leong, Koon-wah ,  Teodorczyk, Maria ,  Kiser, Ernest

    IPC分类号： A61B5/15

    CPC分类号： A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B2562/0295 ,  A61B2562/12

    摘要： Devices, systems and methods are provided for piercing the skin, accessing and collecting physiological sample therein, and measuring a characteristic, e.g. , an analyte concentration, of the sampled physiological sample. The subject devices are in the form of a test strip (2) which includes a biosensor and at least one skin-piercing element (6) which is a planar extension of a portion of the biosensor. At least one fluid pathway (108,128) resides within a portion of the biosensor and within the skin-piercing element. The skin-piercing element has a space-defining configuration therein which acts as a sample fluid pooling area (22,86) upon penetration into the skin. Systems are provided which include one or more test strip devices and a meter (40) for making analyte concentration measurements. Methods for using the devices and systems are also provided.

    摘要翻译： 提供了设备，系统和方法来刺穿皮肤，进入和收集生理样品，并测量其特性，例如， ，样品生理样品的分析物浓度。 本发明装置是测试条（2）的形式，其包括生物传感器和作为生物传感器的一部分的平面延伸的至少一个皮肤刺穿元件（6）。 至少一个流体通道（108,128）位于生物传感器的一部分内并且在皮肤刺穿元件内。 皮肤刺穿元件具有其中的空间限定构造，其在穿透到皮肤中时用作样品流体汇集区域（22,86）。 提供了包括一个或多个测试条装置和用于进行分析物浓度测量的仪表（40）的系统。 还提供了使用装置和系统的方法。