Biological fluid constituent sampling and measurement devices and methods
    2.
    发明公开
    Biological fluid constituent sampling and measurement devices and methods 有权
    Entnahme- und MessvorrichtungfürbiologischeFlüssigkeitskomponenten

    公开(公告)号:EP1266619A1

    公开(公告)日:2002-12-18

    申请号:EP02254038.9

    申请日:2002-06-11

    申请人: Lifescan, Inc.

    IPC分类号: A61B5/15 A61B5/00

    摘要: A device for accessing biological fluid, sampling biological fluid constituents and determining the concentration of at least one target constituent within the accessed biological fluid is provided. The device has at least one micro-piercing member used to penetrate the skin to a selected depth and to access biological fluid, a constituent sampling means and a constituent measuring means. The constituent sampling means comprises a constituent transfer medium, such as a hydrophilic gel material, by which sampled constituents are transferred from the micro-piercing member to the measuring means. The measuring means includes an electrochemical cell having at least one porous electrode through which at least one sampled constituent is caused to enter into the electrochemical cell. Methods of sampling constituents within the skin and measuring the sampled constituents, as well as kits for practicing the invention are provided.

    摘要翻译: 提供了一种用于访问生物流体,取样生物流体成分并确定所访问的生物流体中至少一种目标成分的浓度的装置。 该装置具有至少一个微穿刺构件,用于将皮肤穿透到选定的深度并且访问生物流体,构成采样装置和构成测量装置。 组分取样装置包括诸如亲水性凝胶材料的构成转移介质,通过该成分转移介质将取样的组分从微穿孔构件转移到测量装置。 测量装置包括具有至少一个多孔电极的电化学电池,使至少一个采样成分进入电化学电池。 提供了对皮肤内的成分进行取样并测量取样成分的方法,以及用于实施本发明的试剂盒。

    Physiological sample collection devices and method of using the same
    4.
    发明公开
    Physiological sample collection devices and method of using the same 有权
    生理学Sammelvorrichtungen

    公开(公告)号:EP1360931A1

    公开(公告)日:2003-11-12

    申请号:EP03252879.6

    申请日:2003-05-08

    申请人: Lifescan, Inc.

    IPC分类号: A61B5/15

    摘要: Devices, systems and methods are provided for piercing the skin, accessing and collecting physiological sample therein, and measuring a characteristic, e.g ., an analyte concentration, of the sampled physiological sample. The subject devices are in the form of a test strip which include a biosensor and at least one skin-piercing element which is a planar extension of a portion of the biosensor. At least one fluid pathway resides within a portion of the biosensor and within the skin-piercing element. The skin-piercing element has a space-defining configuration therein which acts as a sample fluid pooling area upon penetration into the skin. Systems are provided which include one or more test strip devices and a meter for making analyte concentration measurements. Methods for using the devices and systems are also provided.

    摘要翻译: 提供了设备,系统和方法,用于刺穿皮肤,进入和收集生理样品,并测量取样的生理样品的特征,例如分析物浓度。 本发明装置是测试条的形式,其包括生物传感器和作为生物传感器的一部分的平面延伸的至少一个皮肤刺穿元件。 至少一个流体通道位于生物传感器的一部分内并且在皮肤刺穿元件内。 皮肤刺穿元件在其中具有空间限定构造,其在穿透到皮肤中时充当样品流体汇集区域。 提供了包括一个或多个测试条装置和用于进行分析物浓度测量的仪表的系统。 还提供了使用装置和系统的方法。

    Biological fluid constituent sampling and measurement devices and methods
    6.
    发明公开
    Biological fluid constituent sampling and measurement devices and methods 有权
    Entnahme- und MessvorrichtungfürbiologischeFlüssigkeitskomponenten

    公开(公告)号:EP2286720A1

    公开(公告)日:2011-02-23

    申请号:EP10179944.3

    申请日:2002-06-11

    申请人: LifeScan, Inc.

    IPC分类号: A61B5/00

    摘要: The invention disclosed herein relates to a biological fluid constituent sampling and concentration measurement device, said device comprising: an array of micro-needles, each micro-needle having an access opening; a layer of hyrdophilic gel material over the array; a first layer of conductive material over the layer of hydrophilic gel material, wherein the first layer of conductive material is porous and further wherein the access openings, the layer of hydrophilic gel material and the first layer of conductive material provide a constituent transfer pathway; and a second layer of conductive material, wherein the first layer of conductive material and the second layer of conductive material are spaced-apart, wherein biological fluid present at the access opening is caused to be transferred to the space between the first and second layers of conductive material.

    摘要翻译: 本文公开的本发明涉及一种生物流体成分采样和浓度测量装置,所述装置包括:微针阵列,每个微针具有进入口; 阵列上的一层嗜性凝胶材料; 在所述亲水凝胶材料层之上的第一层导电材料,其中所述第一导电材料层是多孔的,并且进一步其中所述进入开口,所述亲水凝胶材料层和所述第一导电材料层提供构成转移路径; 以及第二导电材料层,其中所述第一导电材料层和所述第二导电材料层间隔开,其中存在于所述存取开口处的生物流体被转移到所述第一和第二层之间的空间 导电材料。

    Percutaneous biological fluid sampling and analyte measurement devices and methods
    7.
    发明公开
    Percutaneous biological fluid sampling and analyte measurement devices and methods 审中-公开
    经皮生物流体取样和分析物测量装置和方法

    公开(公告)号:EP1266609A3

    公开(公告)日:2004-09-22

    申请号:EP02254052.0

    申请日:2002-06-11

    申请人: Lifescan, Inc.

    IPC分类号: A61B5/15

    CPC分类号: A61B5/1486 A61B5/14532

    摘要: A device for sampling a biological fluid and measuring at least one target constituent within the biological fluid. The device has at least one electrochemical cell having an inner electrode and an outer electrode in a concentrically-spaced relationship. In a preferred embodiment, the outer electrode has a cylindrical configuration having an open distal end and the inner electrode has an elongated configuration positioned co-axially within the outer electrode and a distal end configured to penetrate the skin. The spacing between the electrodes exerts a capillary force on biological fluid present at the open distal end of the outer electrode. A system is also provided which includes a control unit in electrical communication with the electrochemical cell for controlling the selection and measurement of the target constituent. Methods of sampling of biological fluids within the skin and measuring the sampled fluids are also provided, as well as kits comprising one or more of the inventive devices and/or systems.

    Biological fluid constituent sampling and measurement devices and methods
    9.
    发明公开
    Biological fluid constituent sampling and measurement devices and methods 有权
    BiologischeFlüssigkeitsbestandteilentnahmeund Messvorrichtungen und -verfahren

    公开(公告)号:EP2283770A1

    公开(公告)日:2011-02-16

    申请号:EP10179931.0

    申请日:2002-06-11

    申请人: LifeScan, Inc.

    IPC分类号: A61B5/00

    摘要: The invention disclosed herein relates to a biological fluid constituent sampling and concentration measurement device, said device comprising: at least one skin-piercing member comprising a biological fluid access opening; an electrochemical cell for measuring the concentration of analyte within the biological fluid, wherein the electrochemical cell comprises two spaced-apart electrodes defining a reaction chamber, wherein a first of the electrodes is on the same side of the reaction chamber as the skin-piercing member and the second of the electrodes is a porous electrode on the other side of the reaction chamber; and a constituent transfer medium comprising a hydrophilic material in fluid communication with the at least one skin-piercing member and with the reaction chamber.

    摘要翻译: 本文公开的本发明涉及一种生物流体组分采样和浓度测量装置,所述装置包括:至少一个皮肤刺穿构件,其包括生物流体通路口; 用于测量所述生物流体内的分析物浓度的电化学电池,其中所述电化学电池包括限定反应室的两个间隔开的电极,其中所述电极中的第一电极位于所述反应室的与所述皮肤穿孔构件 第二电极是反应室另一侧的多孔电极; 以及构成转移介质,其包括与所述至少一个皮肤穿孔构件和所述反应室流体连通的亲水材料。