Colorimetric test device with reduced error
    2.
    发明公开
    Colorimetric test device with reduced error 有权
    Kolorimetrische Testvorrichtung mit geringerer Fehlerrate

    公开(公告)号:EP1298437A1

    公开(公告)日:2003-04-02

    申请号:EP02256651.7

    申请日:2002-09-25

    申请人: LIFESCAN, INC.

    IPC分类号: G01N33/52 C12Q1/54

    CPC分类号: G01N33/521 C12Q1/54

    摘要: The invention provides testing devices useful in colorimeteric measurements of analytes in which at least a portion of the device's support is of a reflectivity that will not interfere with the meter's error detecting means.

    摘要翻译: 本发明提供了在分析物的色度测量中有用的测试装置,其中装置的支撑件的至少一部分具有不会干扰仪表的误差检测装置的反射率。

    Blood glucose strip having reduced sensitivity to hematocrit
    3.
    发明公开
    Blood glucose strip having reduced sensitivity to hematocrit 失效
    血糖试纸与血细胞比容的敏感性降低

    公开(公告)号:EP1264898A2

    公开(公告)日:2002-12-11

    申请号:EP02078709.9

    申请日:1996-10-16

    申请人: LIFESCAN, INC.

    发明人: Yu, Yeung S.

    IPC分类号: C12Q1/54 G01N33/52

    摘要: A reagent strip for measuring glucose concentration in whole blood has reduced interference of hematocrit with the glucose measurement. When a biological fluid contacts the strip, it causes, in a reagent impregnated in the strip, a color change that is a measure of the glucose concentration in the fluid. However, the color change is also affected by the red blood cell concentration (hematocrit), thereby reducing the accuracy of the glucose measurement. The hematocrit effect is reduced by adding to the reagent an acrylic acid polymer.

    Blood glucose strip having reduced sensitivity to hematocrit
    5.
    发明公开
    Blood glucose strip having reduced sensitivity to hematocrit 失效
    葡萄糖 - 测定仪(SensitivitätfürHämatokrit)

    公开(公告)号:EP0769558A1

    公开(公告)日:1997-04-23

    申请号:EP96307522.1

    申请日:1996-10-16

    申请人: LIFESCAN, INC.

    发明人: Yu, Yeung S.

    IPC分类号: C12Q1/54

    摘要: A reagent strip for measuring glucose concentration in whole blood has reduced interference of hematocrit with the glucose measurement. When a biological fluid contacts the strip, it causes, in a reagent impregnated in the strip, a color change that is a measure of the glucose concentration in the fluid. However, the color change is also affected by the red blood cell concentration (hematocrit), thereby reducing the accuracy of the glucose measurement. The hematocrit effect is reduced by adding to the reagent an acrylic acid polymer.

    摘要翻译: 用于测量全血中葡萄糖浓度的试剂条减少血细胞比容与葡萄糖测量的干扰。 当生物流体接触条带时,其在浸渍在条带中的试剂中导致作为流体中葡萄糖浓度的量度的颜色变化。 然而,颜色变化也受红细胞浓度(血细胞比容)影响,从而降低葡萄糖测量的准确性。 通过向试剂中加入丙烯酸聚合物来降低血细胞比容效应。

    Ambidextrous capillary-fillable test strip
    7.
    发明公开
    Ambidextrous capillary-fillable test strip 审中-公开
    Beidhändigbenutzbarer Teststreifen mitfüllbarerKapillare

    公开(公告)号:EP1471354A2

    公开(公告)日:2004-10-27

    申请号:EP04252359.7

    申请日:2004-04-22

    申请人: LIFESCAN, INC.

    IPC分类号: G01N33/52

    CPC分类号: G01N33/525 G01N33/54386

    摘要: A test strip for detecting an analyte (e.g., blood glucose) in a liquid sample (e.g., whole blood) includes an analytical portion (e.g., a reagent pad), a first edge with a first edge indentation and a second edge with a second edge indentation. The test strip also includes a first capillary channel adapted for providing fluid communication between the first edge indentation and the analytical portion, as well as a second capillary channel adapted for providing fluid communication between the second edge indentation and the analytical portion. Furthermore, the first and second edges are in an opposing relationship (e.g., on left-hand and right-hand sides of the test strip). Also, a test strip and meter combination for detecting an analyte in a liquid sample. The combination includes a test strip with an analytical portion and first and second edges. The first and second edges of the test strip each include an edge indentation with a sample application region. The test strip also includes a first capillary channel adapted for providing fluid communication between the sample application region of the first edge indentation and the analytical portion, as well as a second capillary channel adapted for providing fluid communication between the sample application region of the second edge indentation and the analytical portion. The meter includes a test strip holder configured to receive the test strip in the absence of contact between the sample application regions of the first and second edge indentations and the test strip holder.

    摘要翻译: 测试条(100)包括分析部分,具有包括样品施加区域(112,116)和两个毛细通道的边缘凹陷的两个相对边缘(110,114)。 两个通道在相应边缘压痕的样品施加区域和分析部分的试剂垫之间提供流体连通。 分析部分和通道设置在基部(102)和上部(104)之间。 包括用于检测液体样品中的分析物的条带和仪表组合的独立权利要求。

    Chemical timer for a visual test strip
    8.
    发明公开
    Chemical timer for a visual test strip 失效
    Chemischer Zeitsetzerfüreinen direktablesbaren Reagenzteststreifen

    公开(公告)号:EP0826777A1

    公开(公告)日:1998-03-04

    申请号:EP97306765.5

    申请日:1997-09-02

    申请人: Lifescan, Inc.

    IPC分类号: C12Q1/54 G01N33/52

    摘要: A chemical timer for a direct-reading reagent test strip changes color a predetermined time after a biological fluid is applied to the strip. The strip measures the concentration of an analyte in the fluid. The timer is a dry coating of an indicator, an enzyme-containing reagent that when hydrated can react with glucose to change the color of the indicator, an inhibitor to inhibit the change in color of the indicator, glucose, and optionally, an aldose that does not react with the enzyme in the reagent. Preferably, the reagent and glucose are present in excess in the coating, and the time it takes for the timer color to change can be controlled by the inhibitor concentration. The aldose provides timer stability, probably by interfering with glycosylation by the glucose in the dry state.

    摘要翻译: 用于直接读取试剂测试条的化学计时器在将生物流体施加到条带之后的预定时间内改变颜色。 条带测量流体中分析物的浓度。 定时器是指示剂的干燥涂层,含酶试剂当水合时可与葡萄糖反应以改变指示剂的颜色,抑制剂可抑制指示剂,葡萄糖和任选的醛糖变色, 不与试剂中的酶反应。 优选地,试剂和葡萄糖在涂层中过量存在,并且定时器颜色改变所需的时间可以通过抑制剂浓度来控制。 醛糖提供定时器稳定性,可能通过在干燥状态下干扰葡萄糖的糖基化。

    Reagent test strip for determination of blood glucose
    9.
    发明公开
    Reagent test strip for determination of blood glucose 失效
    Reagenzteststreifen zum Nachweis von Glukose im Blut

    公开(公告)号:EP0799896A2

    公开(公告)日:1997-10-08

    申请号:EP97302307.0

    申请日:1997-04-03

    申请人: LIFESCAN, INC.

    IPC分类号: C12Q1/54 G01N33/52

    摘要: A reagent test strip is adapted for use in a blood glucose meter. A sample of whole blood is applied to one surface of a matrix on the strip and the meter measures the reflectance of the opposite surface of the matrix at about 635 nm and 700 nm and calculates from the reflectance the concentration of glucose in the sample. The portion of the applied sample that penetrates the matrix and is visible from the testing surface does not absorb to any appreciable extent at 700 nm. Nevertheless, the glucose-containing sample interacts with the components of the reagent-containing matrix to cause a change in reflectance at 700 nm that simulates the effect of the blood color. As a result, the strip can be used in meters that measure glucose concentration in whole blood samples in the presence of optically visible hemoglobin.

    摘要翻译: 试剂测试条适用于血糖计。 将全血样品施加到条带上的基质的一个表面上,并且仪器测量在约635nm和700nm处的基质的相对表面的反射率,并根据反射率计算样品中葡萄糖的浓度。 穿透基质并从测试表面可见的所应用样品的部分在700nm处不会被任何明显的程度吸收。 然而,含葡萄糖的样品与含有试剂的基质的组分相互作用,导致700nm处的反射率的变化,模拟血液颜色的影响。 结果是,在光学可见的血红蛋白的存在下,条带可以以测量全血样品中的葡萄糖浓度的米来使用。