A SINGLE-PAD STRIP FOR AN IMPROVED LATERAL FLOW ASSAY AND A TEST DEVICE USING THE SAME

    公开(公告)号:EP2734647B1

    公开(公告)日:2018-10-17

    申请号:EP12817120.4

    申请日:2012-07-20

    申请人: Access Bio, Inc.

    IPC分类号: C12Q3/00 G01N33/52

    摘要: The present invention relates to a strip for an improved lateral flow assay of a biological sample on a single plane and a lateral flow chromatography assay using a test device containing the same. The strip of the present invention consists of a single-pad, which can improve lateral flow assay by providing an easy and simple procedure and clear visual reading. The strip of the present invention is consisted of sample application (sample) zone and reactant-resultant zone where the reaction mixture is deposited (reactant) are all on a same plane. In addition, the present invention provides a chromatographic method wherein hemoglobin is separated from analyte by a differential chromatography on the solid phase. Any interference of detection of the result by hemoglobin is removed by the present invention. The present invention provides advantages including an easy and simple procedure with a quick and clear response.

    STABILIZATION OF ENZYMES BY NICOTINIC ACID
    5.
    发明公开
    STABILIZATION OF ENZYMES BY NICOTINIC ACID 有权
    镇定酶烟碱酸的

    公开(公告)号:EP2994536A1

    公开(公告)日:2016-03-16

    申请号:EP14722216.0

    申请日:2014-05-08

    摘要: The present invention is concerned with means and methods for maintaining and preserving enzymatic activity. In particular, the invention relates to a dry composition comprising a dehydrogenase, a redox cofactor, an agent capable of eliciting at least one measurable change in a property of an indicator reagent in the presence of redox equivalents, an indicator reagent, and at least one pyridine-carboxylic acid or a derivative or salt thereof. The invention further contemplates a diagnostic test element for the determination of an analyte from a body fluid sample and a method for the manufacture of such a test element. Further envisaged by the present invention is the use of a pyridine-carboxylic acid or a derivative thereof for reducing a decrease of the enzymatic activity of at least one enzyme in a composition under dry and/or under humid conditions. Furthermore, contemplated is a method for determining the presence or amount analyte in a body fluid sample based on the test element according to the invention.

    A SINGLE-PAD STRIP FOR AN IMPROVED LATERAL FLOW ASSAY AND A TEST DEVICE USING THE SAME
    6.
    发明公开
    A SINGLE-PAD STRIP FOR AN IMPROVED LATERAL FLOW ASSAY AND A TEST DEVICE USING THE SAME 审中-公开
    EINZELPAD钢带改进的侧流检测和试验设备

    公开(公告)号:EP2734647A4

    公开(公告)日:2015-06-03

    申请号:EP12817120

    申请日:2012-07-20

    申请人: ACCESS BIO INC

    IPC分类号: C12Q3/00 G01N33/52

    摘要: The present invention relates to a strip for an improved lateral flow assay of a biological sample on a single plane and a lateral flow chromatography assay using a test device containing the same. The strip of the present invention consists of a single-pad, which can improve lateral flow assay by providing an easy and simple procedure and clear visual reading. The strip of the present invention is consisted of sample application (sample) zone and reactant-resultant zone where the reaction mixture is deposited (reactant) are all on a same plane. In addition, the present invention provides a chromatographic method wherein hemoglobin is separated from analyte by a differential chromatography on the solid phase. Any interference of detection of the result by hemoglobin is removed by the present invention. The present invention provides advantages including an easy and simple procedure with a quick and clear response.

    A SINGLE-PAD STRIP FOR AN IMPROVED LATERAL FLOW ASSAY AND A TEST DEVICE USING THE SAME
    7.
    发明公开
    A SINGLE-PAD STRIP FOR AN IMPROVED LATERAL FLOW ASSAY AND A TEST DEVICE USING THE SAME 审中-公开
    EINZELPAD钢带改进的侧流检测和试验设备

    公开(公告)号:EP2734647A1

    公开(公告)日:2014-05-28

    申请号:EP12817120.4

    申请日:2012-07-20

    申请人: Access Bio, Inc.

    IPC分类号: C12Q3/00

    摘要: The present invention relates to a strip for an improved lateral flow assay of a biological sample on a single plane and a lateral flow chromatography assay using a test device containing the same. The strip of the present invention consists of a single-pad, which can improve lateral flow assay by providing an easy and simple procedure and clear visual reading. The strip of the present invention is consisted of sample application (sample) zone and reactant-resultant zone where the reaction mixture is deposited (reactant) are all on a same plane. In addition, the present invention provides a chromatographic method wherein hemoglobin is separated from analyte by a differential chromatography on the solid phase. Any interference of detection of the result by hemoglobin is removed by the present invention. The present invention provides advantages including an easy and simple procedure with a quick and clear response.

    Dry test strip for measuring calcium
    8.
    发明公开
    Dry test strip for measuring calcium 有权
    Trockenteststreifen zum Messen von钙

    公开(公告)号:EP2538224A1

    公开(公告)日:2012-12-26

    申请号:EP12165791.0

    申请日:2012-04-26

    申请人: ARKRAY, Inc.

    发明人: Nakamura, Tsutomu

    IPC分类号: G01N33/84 G01N33/52

    摘要: A dry test strip for measuring calcium (1,10) is characterized by comprising a support (2), a reagent layer (4) provided on the support (2), and a reagent holding layer (5) provided on the reagent layer (4), and containing, as reagents, o-cresolphthalene complexone, a magnesium selective masking agent, and a pH buffer for adjusting the pH of the environment for reaction of the o-cresolphthalene complexone with calcium to 10.0-11.0, wherein such reagents are present in either the reagent layer (4) or the reagent holding layer (5) or the both layers.

    摘要翻译: 用于测量钙(1,10)的干试条的特征在于包含支撑体(2),设置在支撑体(2)上的试剂层(4)和设置在试剂层上的试剂保持层(5) 4),并含有作为试剂的邻甲酚酞配合物,镁选择性屏蔽剂和pH缓冲剂,用于调节邻甲酚酞配合物与钙的反应环境的pH至10.0-11.0,其中这些试剂是 存在于试剂层(4)或试剂保持层(5)或两层中。