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1.发明公开UBIQUITIN SPECIFIC PROTEASES RESPONSIBLE FOR MCL-1 STABILITY AND USES THEREOF 审中-公开泛素蛋白酶FOR MCL-1稳定性和使用
公开(公告)号：EP2344666A2
公开(公告)日：2011-07-20
申请号：EP09799134.3
申请日：2009-10-29
CPC分类号： G01N33/5011 , A61K38/00 , C12Q1/37
摘要： Use of a polypeptide selected from the group consisting of USP13, USP26, USP38, USP42 or USP46 as a screening tool for an agent for treating cancer.
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2.发明公开
公开(公告)号：EP2084163A2
公开(公告)日：2009-08-05
申请号：EP07848828.5
申请日：2007-10-25
申请人： Hybrigenics S.A.
发明人： GUEDAT, Philippe , JACQ, Xavier , COLLAND, Frédéric , DAVIET, Laurent , FORMSTECHER, Etienne , RAIN, Jean-Christophe , COLOMBO, Matteo
IPC分类号： C07D487/04 , A61K31/53 , A61K31/4196 , A61K31/41 , A61P35/00 , A61P33/00 , A61P25/00
CPC分类号： C07D487/04
摘要： The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use : Formule (I) wherein R3, R4, R5, R6, Y, Het1, T, U, V, W, X, Ru, Rv and Rw are as defined in claim 1
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3.发明公开INHIBITORS OF CYSTEINE PROTEASES, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS 有权半胱氨酸蛋白酶抑制剂，其药物组合物及其治疗用途
公开(公告)号：EP1963328A2
公开(公告)日：2008-09-03
申请号：EP06831646.2
申请日：2006-12-05
申请人： Hybrigenics S.A.
发明人： GUEDAT, Philippe , BOISSY, Guillaume , BORG-CAPRA, Catherine , COLLAND, Frédéric , DAVIET, Laurent , FORMSTECHER, Etienne , JACQ, Xavier , RAIN, Jean-Christophe , DELANSORNE, Rémi , PERETTO, Ilaria , VIGNANDO, Stefano
IPC分类号： C07D487/04 , A61P37/02 , A61K31/4192
CPC分类号： C07D487/04
摘要： The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
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4.发明公开
公开(公告)号：EP1912954A2
公开(公告)日：2008-04-23
申请号：EP06808884.8
申请日：2006-07-26
申请人： Hybrigenics S.A.
发明人： GUEDAT, Philippe , BOISSY, Guillaume , BORG-CAPRA, Catherine , COLLAND, Frédéric , DAVIET, Laurent , FORMSTECHER, Etienne , JACQ, Xavier , RAIN, Jean-Christophe , DELANSORNE, Rémi , VALLESE, Stefania , COLOMBO, Matteo
IPC分类号： C07D241/38 , A61K31/495 , A61P35/00 , A61P25/28
CPC分类号： C07D241/38
摘要： The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
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5.发明授权INHIBITORS OF CYSTEINE PROTEASES, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS 有权半胱氨酸蛋白酶抑制剂，其药物组合物及其治疗用途
公开(公告)号：EP1963328B1
公开(公告)日：2013-10-30
申请号：EP06831646.2
申请日：2006-12-05
申请人： Hybrigenics S.A.
发明人： GUEDAT, Philippe , BOISSY, Guillaume , BORG-CAPRA, Catherine , COLLAND, Frédéric , DAVIET, Laurent , FORMSTECHER, Etienne , JACQ, Xavier , RAIN, Jean-Christophe , DELANSORNE, Rémi , PERETTO, Ilaria , VIGNANDO, Stefano
IPC分类号： C07D487/04 , A61P37/02 , A61K31/4192
CPC分类号： C07D487/04
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6.发明授权
公开(公告)号：EP1912954B1
公开(公告)日：2011-03-09
申请号：EP06808884.8
申请日：2006-07-26
申请人： Hybrigenics S.A.
发明人： GUEDAT, Philippe , BOISSY, Guillaume , BORG-CAPRA, Catherine , COLLAND, Frédéric , DAVIET, Laurent , FORMSTECHER, Etienne , JACQ, Xavier , RAIN, Jean-Christophe , DELANSORNE, Rémi , VALLESE, Stefania , COLOMBO, Matteo
IPC分类号： C07D241/38 , A61K31/495 , A61P35/00 , A61P25/28
CPC分类号： C07D241/38
摘要： The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
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7.发明授权
公开(公告)号：EP2084163B1
公开(公告)日：2017-04-12
申请号：EP07848828.5
申请日：2007-10-25
申请人： Hybrigenics S.A.
发明人： GUEDAT, Philippe , JACQ, Xavier , COLLAND, Frédéric , DAVIET, Laurent , FORMSTECHER, Etienne , RAIN, Jean-Christophe , COLOMBO, Matteo
IPC分类号： C07D487/04 , A61K31/53 , A61K31/4196 , A61K31/41 , A61P35/00 , A61P33/00 , A61P25/00
CPC分类号： C07D487/04
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