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1.发明公开SYSTEMS USING A LEVITATING, ROTATING PUMPING OR MIXING ELEMENT AND RELATED METHODS 审中-公开系统用浮动型旋转泵或混合元件和类似的方法使用
公开(公告)号：EP1336243A2
公开(公告)日：2003-08-20
申请号：EP01986970.0
申请日：2001-10-09
CPC分类号： F04D29/048 , A61M1/101 , A61M1/1015 , A61M1/1036 , A61M1/127 , B01F7/00908 , B01F7/162 , B01F13/0018 , B01F13/002 , B01F13/0818 , B01F13/0827 , B01F13/0863 , B01F13/0872 , B01F15/00831 , B01F15/0085 , B01F2015/061 , F04D13/026 , F16C32/0438 , F16C37/005
摘要： A system for pumping or mixing a fluid using a levitating, rotating pumping or mixing element and various other components for use in a pumping or mixing system as disclosed. The pumping or mixing element is placed in a fluid-containing vessel in close proximity to a superconducting element. A cooling source thermally linked to the superconducting element provides the necessary cooking to induce levitation in the pumping or mixing element. The superconducting element may be thermally isolated, such that the pumping or mixing element, the vessel, and any fluid contained therein are not exposed to the cold temperatures required to produce the desired superconductive effects and the resulting levitation. By using means external to the vessel to rotate and/or stabilize the pumping or mixing element levitating in the fluid, including possibly rotating the superconducting element itself or moving it relative to the vessel, the desired effective pumping or mixing action may be provided.
摘要翻译： 一种如游离缺失盘泵送或使用漂浮混合的流体，旋转泵送或在泵送混合元件和各种其它组件以供使用或混合系统的系统。 泵送或混合元件被放置在含有流体的容器在靠近一个超导元件。 热连接到超导元件的冷却源提供了必要的烹调诱导悬浮在泵送或混合元件。 超导元件可以是热隔离的，检查没有泵送或混合元件，所述容器中，并且其中所含的不暴露于产生所需的超导效果和所得到的悬浮所需的冷温度的任何流体。 通过使用构件在容器外部旋转和/或稳定的泵送或混合元件在流体中漂浮，包括可能本身旋转超导元件或移动它相对于容器中，可以提供期望的有效泵送或混合作用。
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公开(公告)号：EP1534412B1
公开(公告)日：2010-08-18
申请号：EP02800450.5
申请日：2002-10-02
申请人： Levtech Inc.
CPC分类号： B01F15/00837 , B01F1/0011 , B01F7/162 , B01F13/0818 , B01F13/0827 , B01F13/0845 , B01F13/0863 , B01F15/00071 , B01F15/00824 , B01F15/00831 , B01F15/0085 , B01F2215/0032 , B01F2215/0034 , B01F2215/0036 , B01F2215/0037 , B01F2215/0073
摘要： A vessel (10) in which a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device (24) is disclosed. In one aspect, the vessel is a bag including a first receiver (16) for receiving and holding a fluid-agitating element (18) at a home location. The first receiver may be in the form of an inwardly projecting post (20) having an oversized portion for capturing the fluid-agitating element. Use of this feature in completely rigid vessels where the fluid-agitating element is free of direct attachment from a first receiver having an oversized portion is also disclosed. In another aspect, the vessel or bag further includes a second receiver (26) for receiving a portion of an external structure, such as a motive device, and aligning the vessel relative thereto.
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公开(公告)号：EP1701780A1
公开(公告)日：2006-09-20
申请号：EP05705228.4
申请日：2005-01-07
申请人： Levtech Inc.
IPC分类号： B01F3/04
CPC分类号： B01F15/00123 , B01F3/04248 , B01F3/04262 , B01F3/04531 , B01F7/162 , B01F13/00 , B01F13/08 , B01F13/0827 , B01F15/00207 , B01F15/00824 , B01F15/0085 , B01F2215/0037 , C12M23/14 , C12M23/22 , C12M27/02 , C12M29/06
摘要： Bioprocessing vessel intended for receiving a fluid, comprising a bag (10) capable of receiving and holding the fluid, the bag having a rigid receiver (200) facing an interior, and an at least translucent tube (G) having a closed end for insertion through the receiver and in communication with the interior.
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公开(公告)号：EP2271906A1
公开(公告)日：2011-01-12
申请号：EP09755354.9
申请日：2009-03-26
申请人： Levtech Inc.
摘要： An apparatus for integrity testing a first container having a flexible body at least partially defining a first interior chamber using a second container having a second, preferably sterilized interior chamber at least partially filled with a detectable gas. A sensor associated with a detection chamber for receiving the flexible container, and possibly the second container as well, senses the presence of the detectable gas external to the first interior chamber in the event of a leak of the detectable gas therefrom. Related methods also involve integrity testing of fluid processing bags and other types of flexible containers.
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公开(公告)号：EP1948779A1
公开(公告)日：2008-07-30
申请号：EP06826977.8
申请日：2006-10-26
申请人： Levtech Inc.
IPC分类号： C12M1/06
CPC分类号： C12M27/02 , B01F3/04262 , B01F7/0005 , B01F7/00575 , B01F7/162 , B01F13/0863 , B01F15/00831 , B01F15/0085 , B01F2003/0429 , C12M23/14 , C12M23/26 , C12M27/04 , C12M29/06 , C12M41/34
摘要： A bioreactor and related methods are for use in bioprocessing in which a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device. In one embodiment, the bioreactor includes a mixer and a movable sparger. The mixer may take the form of a rotational wand mixer, and may further comprise a magnetic impeller. In another embodiment, the bioreactor includes a rotational wand mixer and an integral sparger. In still another embodiment, the bioreactor comprises a bag including a rotational wand mixer having rigid blades attached thereto.
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公开(公告)号：EP1332299A1
公开(公告)日：2003-08-06
申请号：EP01986751.4
申请日：2001-01-12
申请人： Levtech Inc.
CPC分类号： F04D29/048 , A61M1/1006 , A61M1/101 , A61M1/1015 , A61M1/1036 , A61M1/127 , B01F13/0818 , B01F2015/061 , F04D13/027 , F16C32/0438 , F16C37/005
摘要： A kit for assisting in the set-up of a fluid pumping or mixing system including a superconducting element capable of reaching a transition temperature during a field cooling process is disclosed. In one embodiment, the kit comprises at least one pumping or mixing element including a levitation magnet and at least one charging magnet substantially corresponding in size, shape, and magnetic field distribution to the levitation magnet. The presence of the charging magnet adjacent the superconducting element during the field cooling process enables stable levitation of the pumping or mixing element, including when in a fluid-filled vessel positioned adjacent the superconducting element.
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公开(公告)号：EP1332299B1
公开(公告)日：2010-03-03
申请号：EP01986751.4
申请日：2001-01-12
申请人： Levtech Inc.
CPC分类号： F04D29/048 , A61M1/1006 , A61M1/101 , A61M1/1015 , A61M1/1036 , A61M1/127 , B01F13/0818 , B01F2015/061 , F04D13/027 , F16C32/0438 , F16C37/005
摘要： A kit for assisting in the set-up of a fluid pumping or mixing system including a superconducting element capable of reaching a transition temperature during a field cooling process is disclosed. In one embodiment, the kit comprises at least one pumping or mixing element including a levitation magnet and at least one charging magnet substantially corresponding in size, shape, and magnetic field distribution to the levitation magnet. The presence of the charging magnet adjacent the superconducting element during the field cooling process enables stable levitation of the pumping or mixing element, including when in a fluid-filled vessel positioned adjacent the superconducting element.
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公开(公告)号：EP1999446A2
公开(公告)日：2008-12-10
申请号：EP07758988.5
申请日：2007-03-21
申请人： Levtech Inc.
IPC分类号： G01M3/16
摘要： An apparatus detects a leak of an electrically conductive fluid from a disposable plastic bag used in mixing applications, such as during bioprocessing in a sterile environment. In one embodiment, the bag is associated with a sensor for detecting a leak from an interior compartment. The sensor may be arranged to detect either a leak internal to the at least two material layers of the bag or external to the outer layer, or both. Related methods are also disclosed.
摘要翻译： 设备检测来自用于混合应用的一次性塑料袋的导电流体泄漏，例如在无菌环境中的生物处理期间。 在一个实施例中，袋子与用于检测来自内部隔室的泄漏的传感器相关联。 传感器可以布置成检测袋子的至少两个材料层内或外层外部的泄漏，或两者。 还公开了相关的方法。
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9.发明授权APPARATUS AND METHOD FOR MIXING MATERIALS SEALED IN A CONTAINER UNDER STERILE CONDITIONS 有权DEVICE AND METHOD FOR材料在无菌条件下的容器中的混音包括
公开(公告)号：EP1365854B1
公开(公告)日：2011-05-25
申请号：EP02718914.1
申请日：2002-02-05
申请人： Levtech Inc.
CPC分类号： B01F7/00325 , B01F7/0005 , B01F7/1695 , B01F15/00071 , B01F15/00824 , B01F15/0085 , B01F15/0212 , B01F2015/00084 , B01F2215/0037 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要： A mixing bag (12) usable in chemical and bioprocessing procedures that is hermetically sealed about a tube (14) that is closed within the bag but extends out through a seal (18) and adapted to receive a rotatable rigid rod (16) of a predetermined shape for mixing the materials in the bag (12). After the mixing is completed the rod (16) can be removed from the tube (14) within the bag (12), and the bag (12) along with other components including the tube (14) and spacers 22 can be moved for further processing as desired. The bag (12) along with the tube (14) can be discarded once processing has been completed while rod 16 can be used again.
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10.发明公开ROLLER BEARING FOR A FLUID-AGITATING ELEMENT AND ASSOCIATED VESSEL 审中-公开滚珠轴承一个FLÜSSIGKEITSANTREIBENDES元与相应的容器
公开(公告)号：EP2114554A1
公开(公告)日：2009-11-11
申请号：EP08730431.7
申请日：2008-02-21
申请人： Levtech Inc.
IPC分类号： B01F13/08
CPC分类号： B01F7/162 , B01F13/0827 , B01F15/00831 , B01F15/0085 , F16C19/10 , F16C33/32 , F16C33/62
摘要： In a vessel, such as a flexible bag, a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device and supported by a bearing, such as a roller bearing. The bearing may comprise a thrust bearing having at least one race fabricated of polyvinylidene fluoride and a plurality of associated rollers, preferably comprising a ceramic material, such as silicon nitride. Experiments show beneficial results in terms of particle generation when this particular combination of materials is used in the context of agitating fluids, and benefits as well when different materials are used to form the rollers.
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