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公开(公告)号：EP2839278B1
公开(公告)日：2017-09-27
申请号：EP13706853.2
申请日：2013-02-13
发明人： VLASSOV, Alexander , LI, Mu , ZERINGER, Emily , CONRAD, Richard
IPC分类号： G01N33/50
CPC分类号： G01N1/34 , C12Q1/6806 , G01N33/5005 , G01N33/5076 , G01N33/92
摘要： Disclosed are methods, compositions and kits for the isolation of exosomes from biological fluids and tissues. Volume-excluding polymers are used to precipitate exosomes from biological samples thereby allowing exosome isolation by low-speed (benchtop) centrifugation or filtration. Further fractionation of exosomes after precipitation is also described.
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公开(公告)号：EP2839278A1
公开(公告)日：2015-02-25
申请号：EP13706853.2
申请日：2013-02-13
发明人： VLASSOV, Alexander , LI, Mu , ZERINGER, Emily , CONRAD, Richard
IPC分类号： G01N33/50
CPC分类号： G01N1/34 , C12Q1/6806 , G01N33/5005 , G01N33/5076 , G01N33/92
摘要： Disclosed are methods, compositions and kits for the isolation of exosomes from biological fluids and tissues. Volume-excluding polymers are used to precipitate exosomes from biological samples thereby allowing exosome isolation by low-speed (benchtop) centrifugation or filtration. Further fractionation of exosomes after precipitation is also described.
摘要翻译： 公开了用于从生物流体和组织分离外来体的方法，组合物和试剂盒。 使用不含体积聚合物来从生物样品中沉淀外来体，从而通过低速（台式）离心或过滤允许外来体分离。 还描述了沉淀后进一步分离外泌体。
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公开(公告)号：EP3327440A1
公开(公告)日：2018-05-30
申请号：EP17191391.6
申请日：2013-02-13
发明人： VLASSOV, Alexander , LI, Mu , ZERINGER, Emily , CONRAD, Richard
摘要： Disclosed are methods, compositions and kits for the isolation of exosomes from biological fluids and tissues. Volume-excluding polymers are used to precipitate exosomes from biological samples thereby allowing exosome isolation by low-speed (benchtop) centrifugation or filtration. Further fractionation of exosomes after precipitation is also described.
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公开(公告)号：EP3327440B1
公开(公告)日：2020-01-08
申请号：EP17191391.6
申请日：2013-02-13
发明人： VLASSOV, Alexander , LI, Mu , ZERINGER, Emily , CONRAD, Richard
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公开(公告)号：EP2558578A1
公开(公告)日：2013-02-20
申请号：EP11715836.0
申请日：2011-04-13
IPC分类号： C12N15/113
CPC分类号： C12N15/113 , A61K31/713 , A61K47/50 , C12N15/111 , C12N2310/113 , C12N2310/141 , C12N2310/321 , C12N2310/322 , C12N2310/3231 , C12N2310/332 , C12N2310/3515 , C12N2310/3519 , C12N2310/51 , C12N2310/531 , C12N2330/31
摘要： The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs.
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公开(公告)号：EP3347491A1
公开(公告)日：2018-07-18
申请号：EP16778500.5
申请日：2016-09-09
发明人： VLASSOV, Alexander , LAROCCA, Sarah , LI, Mu
CPC分类号： C12N15/1003 , C12Q1/6806 , C12Q1/686 , G01N33/56938 , G01N33/574 , G01N2800/06
摘要： Compositions and methods for nucleic acid isolation from an environmental or biological sample comprising nucleic acid-analysis interferents, particularly from microbiome-containing samples, are provided.
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7.发明授权COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION 有权ZUSAMMENSETZUNGEN UND VERFAHREN ZUR HEMMUNG DER FUNKTION VONNUKLEINSÄUREN
公开(公告)号：EP2558578B1
公开(公告)日：2015-10-28
申请号：EP11715836.0
申请日：2011-04-13
IPC分类号： C12N15/113
CPC分类号： C12N15/113 , A61K31/713 , A61K47/50 , C12N15/111 , C12N2310/113 , C12N2310/141 , C12N2310/321 , C12N2310/322 , C12N2310/3231 , C12N2310/332 , C12N2310/3515 , C12N2310/3519 , C12N2310/51 , C12N2310/531 , C12N2330/31
摘要： The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs.
摘要翻译： 本发明一般涉及通过序列特异性结合抑制靶核酸功能的组合物和方法。 组合物和方法可用于抑制微RNA和其他相对较短的非编码RNA。
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