公开(公告)号：EP0852336B1

公开(公告)日：2004-04-14

申请号：EP97310655.2

申请日：1997-12-30

申请人： Lifescan, Inc.

发明人： Douglas, joel ,  Kiser, Ernest ,  Tomasco, Michael F. ,  Dato, Remedios ,  Rice, Edward G. ,  Tuohy, Deborah P. ,  Maxson, Mark ,  Witko, Zbigniew ,  Segelke, Scott

IPC分类号： G01N33/558 ,  C12Q1/54

CPC分类号： G01N33/66 ,  C12Q1/54 ,  G01N33/521 ,  G01N33/523 ,  G01N33/526 ,  G01N33/558

公开(公告)号：EP0852336A1

公开(公告)日：1998-07-08

申请号：EP97310655.2

申请日：1997-12-30

申请人： Lifescan, Inc.

发明人： Douglas, joel ,  Kiser, Ernest ,  Tomasco, Michael F. ,  Dato, Remedios ,  Rice, Edward G. ,  Tuohy, Deborah P. ,  Maxson, Mark ,  Witko, Zbigniew ,  Segelke, Scott

IPC分类号： G01N33/558 ,  C12Q1/54

CPC分类号： G01N33/66 ,  C12Q1/54 ,  G01N33/521 ,  G01N33/523 ,  G01N33/526 ,  G01N33/558

摘要： A multilayer reagent test strip measures the concentration of analyte in a liquid sample that is applied to it. The sample is guided to a number of assay areas arrayed along the strip, where the analyte can react with a reagent to cause a color change. Each assay area also includes an inhibitor for the color-change reaction. The inhibitor concentration increases in successive assay areas; thus, the number of areas that change color is a measure of the analyte concentration. The test strip is particularly adapted for measuring glucose in a whole blood sample. In a preferred embodiment, the sample is guided to the assay areas along a path formed by crushing selected areas of a membrane, and the assay areas are uncrushed areas of the membrane.

摘要翻译： 多层试剂测试条测量施加于其上的液体样品中分析物的浓度。 将样品引导到沿着条带排列的多个测定区域，其中分析物可以与试剂反应以引起颜色变化。 每个测定区域还包括用于变色反应的抑制剂。 连续测定区域的抑制剂浓度增加; 因此，改变颜色的区域的数量是分析物浓度的量度。 测试条特别适用于测量全血样品中的葡萄糖。 在优选的实施方案中，将样品沿着通过破碎膜的选定区域形成的路径被引导到测定区域，并且测定区域是膜的未破碎区域。

公开(公告)号：EP0759555A2

公开(公告)日：1997-02-26

申请号：EP96305720.3

申请日：1996-08-02

申请人： LIFESCAN, INC.

发明人： Douglas, Joel ,  Tomasco, Michael F. ,  Kiser, Ernest ,  Dato, Remedios ,  Rice, Edward G. ,  Tuohy, Deborah P. ,  Maxson, Mark

IPC分类号： G01N33/52

CPC分类号： G01N33/526 ,  C12Q1/54

摘要： A multilayer reagent test strip measures the concentration of analyte in a liquid sample that is applied to it. The sample is guided to a number of assay areas arrayed along the strip, where the analyte can react with a reagent to cause a color change. Each assay area also includes an inhibitor for the color-change reaction. The inhibitor concentration increases in successive assay areas; thus, the number of areas that change color is a measure of the analyte concentration. The test strip is particularly adapted for measuring glucose in a whole blood sample. In a preferred embodiment, the sample is guided to the assay areas along a path formed by crushing selected areas of a membrane, and the assay areas are uncrushed areas of the membrane.

摘要翻译： 多层试剂测试条测量应用于其上的液体样品中分析物的浓度。 将样品引导至沿着条带排列的多个分析区域，其中分析物可以与试剂反应以引起颜色变化。 每个测定区域还包括用于颜色变化反应的抑制剂。 在连续测定区域中抑制剂浓度增加; 因此，改变颜色的区域的数量是分析物浓度的量度。 测试条特别适用于测量全血样品中的葡萄糖。 在一个优选的实施方案中，样品沿着通过压碎膜的选定区域而形成的路径被引导至测定区域，并且测定区域是膜的未压碎区域。