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公开(公告)号：EP1974209A2
公开(公告)日：2008-10-01
申请号：EP06851774.7
申请日：2006-11-30
Applicant: Massachusetts Institute of Technology
Inventor： SCHWOEBEL, Eric , HARPER, James , PETROVICK, Martha S. , NARGI, Frances , HOLLIS, Mark , JOHNSON, Bernadette , LACIRIGNOLA, Joseph , MATHEWS, Richard , HOGAN, Kristine , VIAN, Trina , HEFF, Allan , HENNESSY, Mark , PALCHAUDHURI, Songeeta , RIDER, Todd
IPC: G01N33/50
CPC classification number: G01N33/54373 , G01N21/6428 , G01N21/75
Abstract: The invention described herein provides methods for the detection of target particles, such as pathogens, soluble antigens, nucleic acids, toxins, chemicals, plant pathogens, blood borne pathogens, bacteria, viruses and the like. Also described is an emittor cell comprising a receptor, wherein the receptor can be an antibody or an Fc receptor, and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more receptors on the emittor cell. Also provided are optoelectronic sensor devices for detecting a target particle in a sample, including in a plurality of samples.
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Patent Agency Ranking
公开(公告)号：EP1831404A2
公开(公告)日：2007-09-12
申请号：EP05858641.3
申请日：2005-11-30
Applicant: Massachusetts Institute of Technology (MIT)
Inventor： SCHWOEBEL, Eric, D. , HARPER, James, D. , PETROVICK, Martha, S. , NARGI, Frances, E. , RIDER, Todd, H. , HOGAN, Kristine, E. , MATHEWS, Richard, H. , LACIRIGNOLA, Joseph , HENNESSY, Mark , VIAN, Trina, R. , JOSEPH, Rose, M. , UTTARO, Raymond , SHAUN, Berry , HOLLIS, Mark, A. , JOHNSON, Bernadette
IPC: C12Q1/68
CPC classification number: G01N33/5304 , C12M1/3461 , C12M1/3476 , C12Q1/6825 , G01N21/6428 , G01N21/6454 , G01N33/582 , C12Q2565/619 , C12Q2563/131
Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
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公开(公告)号：EP1364070A2
公开(公告)日：2003-11-26
申请号：EP02726568.5
申请日：2002-02-06
Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor： HARPER, James, Douglas , MATHEWS, Richard, Hart , JOHNSON, Bernadette , PETROVICK, Martha, Susan , RUNDELL, Ann , NARGI, Frances, Ellen , STEPHENS, Timothy , MENDENHALL, Linda, Marie , HOLLIS, Mark, Alexander , YOUNG, Albert, M. , RIDER, Todd, Harrison , SCHWOEBEL, Eric, David , VIAN, Trina, Rae
IPC: C12Q1/68 , G01N27/26 , G01N33/53 , G01N33/543 , G01N33/552 , G01N33/554 , H01L21/203 , H01L29/00
CPC classification number: G01N33/554 , G01N15/0205 , G01N21/07 , G01N21/64 , G01N21/6428 , G01N21/75 , G01N21/76 , G01N33/54373 , G01N33/54393 , G01N33/56983 , G01N33/582 , G01N2021/6439 , G01N2201/025 , G01N2201/061 , Y10S435/808 , Y10S436/805
Abstract: The invention relates to optoelectronic systems for detecting one or more target particles (Figure 4). The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, thereby producing a measurable optical signal.
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公开(公告)号：EP1974209B1
公开(公告)日：2013-06-19
申请号：EP06851774.7
申请日：2006-11-30
Applicant: Massachusetts Institute of Technology
Inventor： SCHWOEBEL, Eric , HARPER, James , PETROVICK, Martha S. , NARGI, Frances , HOLLIS, Mark , JOHNSON, Bernadette , LACIRIGNOLA, Joseph , MATHEWS, Richard , HOGAN, Kristine , VIAN, Trina , HEFF, Allan , HENNESSY, Mark , PALCHAUDHURI, Songeeta , RIDER, Todd
IPC: G01N33/543 , G01N33/566
CPC classification number: G01N33/54373 , G01N21/6428 , G01N21/75
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公开(公告)号：EP1831404B1
公开(公告)日：2010-04-28
申请号：EP05858641.3
申请日：2005-11-30
Applicant: Massachusetts Institute of Technology (MIT)
Inventor： SCHWOEBEL, Eric, D. , HARPER, James, D. , PETROVICK, Martha, S. , NARGI, Frances, E. , RIDER, Todd, H. , HOGAN, Kristine, E. , MATHEWS, Richard, H. , LACIRIGNOLA, Joseph , HENNESSY, Mark , VIAN, Trina, R. , JOSEPH, Rose, M. , UTTARO, Raymond , BERRY, Shaun , HOLLIS, Mark, A. , JOHNSON, Bernadette
IPC: C12Q1/68
CPC classification number: G01N33/5304 , C12M1/3461 , C12M1/3476 , C12Q1/6825 , G01N21/6428 , G01N21/6454 , G01N33/582 , C12Q2565/619 , C12Q2563/131
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公开(公告)号：EP1364070B1
公开(公告)日：2006-11-15
申请号：EP02726568.5
申请日：2002-02-06
Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor： HARPER, James, Douglas , MATHEWS, Richard, Hart , JOHNSON, Bernadette , PETROVICK, Martha, Susan , RUNDELL, Ann , NARGI, Frances, Ellen , STEPHENS, Timothy , MENDENHALL, Linda, Marie , HOLLIS, Mark, Alexander , YOUNG, Albert, M. , RIDER, Todd, Harrison , SCHWOEBEL, Eric, David , VIAN, Trina, Rae
CPC classification number: G01N33/554 , G01N15/0205 , G01N21/07 , G01N21/64 , G01N21/6428 , G01N21/75 , G01N21/76 , G01N33/54373 , G01N33/54393 , G01N33/56983 , G01N33/582 , G01N2021/6439 , G01N2201/025 , G01N2201/061 , Y10S435/808 , Y10S436/805
Abstract: The invention relates to optoelectronic systems for detecting one or more target particles (Figure 4). The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, thereby producing a measurable optical signal.
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