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公开(公告)号：EP1207791A1
公开(公告)日：2002-05-29
申请号：EP00965597.8
申请日：2000-08-07
发明人： CRAGG, Andrew, H. , WALKER, Blair, D. , PERL, John, II , JONES, Michael , GREENE, George, Robert , WALLACE, George , GREFF, Richard, J.
IPC分类号： A61B17/12
CPC分类号： A61B17/12195 , A61B17/00491 , A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/12168 , A61B17/12172 , A61B17/12177 , A61B17/12186 , A61B17/1219 , A61B2017/00495 , A61B2017/00876 , A61B2017/00893 , A61B2017/1205 , A61B2017/12059 , A61B2017/12063 , A61M25/00 , A61M25/0028 , A61M25/0097 , A61M2025/0036 , A61M2025/004
摘要： A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.
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公开(公告)号：EP1207791B1
公开(公告)日：2004-10-06
申请号：EP00965597.8
申请日：2000-08-07
发明人： CRAGG, Andrew, H. , WALKER, Blair, D. , PERL, John, II , JONES, Michael , GREENE, George, Robert , WALLACE, George , GREFF, Richard, J.
IPC分类号： A61B17/12
CPC分类号： A61B17/12195 , A61B17/00491 , A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/12168 , A61B17/12172 , A61B17/12177 , A61B17/12186 , A61B17/1219 , A61B2017/00495 , A61B2017/00876 , A61B2017/00893 , A61B2017/1205 , A61B2017/12059 , A61B2017/12063 , A61M25/00 , A61M25/0028 , A61M25/0097 , A61M2025/0036 , A61M2025/004
摘要： A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.
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公开(公告)号：EP0885024A1
公开(公告)日：1998-12-23
申请号：EP97904847.0
申请日：1997-01-27
发明人： EVANS, Scott , PERL, John, II , GREFF, Richard, J.
CPC分类号： A61L24/0015 , A61L24/001 , A61L24/02 , A61L24/04 , A61L31/02 , A61L2300/418 , A61L2300/44 , A61L2430/36
摘要： Disclosed are methods useful for treating vascular lesions wherein a non-particulate agent such as a metal coil is introduced into a vascular site (e.g., an aneurysm cavity) in conjunction with an embolizing composition comprising a biocompatible polymer and a biocompatible solvent. The biocompatible solvent is miscible or soluble in blood and also solubilizes the polymer during delivery. The biocompatible polymer is selected to be soluble in the biocompatible solvent but insoluble in blood. Upon contact with the blood, the biocompatible solvent dissipates from the embolic composition whereupon the biocompatible polymer precipitates. Precipitation of the polymer in the presence of the non-particulate agent permits the agent to act as a structural lattice for the growing polymer precipitate. In another embodiment, the biocompatible polymer composition can be replaced with a biocompatible prepolymer composition containing a biocompatible prepolymer.
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