Abstract:
Aneurysm treatment apparatus includes a steerable catheter assembly (10) having a catheter (12) with a steerable distal end (14). A pouch (40) is disposed over the distal end (14) of the catheter (12) so as to be in co-axial overlying relationship therewith. A constraining sheath (60) is disposed over a major portion of the pouch (40) and has a proximal sheath portion (64) which is bonded to the catheter (12). The sheath (60) terminates short of the distal end (26) of the catheter (12), so as to leave a distal end of the pouch (40) exposed. The steerable catheter can be steered into an aneurysm sac (80) and filler material fed through the catheter (12) in order to fill chamber (50) of the pouch (40). The pouch (40) will expand from its distal end (44) with filler material and gradually slide off the sheath (12) as it fills the aneurysm sac (80). The sheath (60) prevents the pouch (40) from expanding proximally, and potentially adversely affecting the filling process.
Abstract:
Methods, devices, and systems for mechanically reducing the volume of the lung. Some embodiments are a device for reducing the volume of a lung, comprising a distal anchor, a proximal anchor, and a tether extending between the distal and proximal anchors, the device configured so that the distance between the anchors measured along the tether can be increased or decreased and maintained after release of a delivery device. Some embodiments are a method of reducing the volume of a lung, comprising endobronchially deploying an anchoring device within the lung, the anchoring device comprising a distal anchor, a proximal anchor, and a tether extending between the distal and proximal anchors, the device configured such that the distance between the distal and proximal anchors measured along the tether can be increased or decreased and then maintained after release of the anchoring device from a delivery device, reducing the volume of the lung by decreasing the distance between the distal and proximal anchors, and maintaining the decreased distance.
Abstract:
Disclosed are compositions, methods and kits to control bleeding through the use of an internal occluder based on polymeric solutions, including use of reverse thermosensitive polymers in nephron-sparing surgeries, which produces a completely bloodless surgical field, allowing speedy resection. In certain embodiments, after a certain amount of time, the flow gradually resumes, with no apparent adverse consequences to the kidney. In certain embodiments, return of blood flow may be accelerated by cooling the kidney. The compositions, methods and kits for perfusive organ hemostasis can also be used to simplify or to enable other organ surgeries or interventional procedures, including liver surgery, prostate surgery, brain surgery, surgery of the uterus, spleen surgery and any surgery on any highly vascularized organs.
Abstract:
The present invention provides methods and apparatus for the endoluminal positioning of an intraluminal prosthesis at a target location within a body lumen. The device may comprise a porous, multi-layer prosthesis that can include several different tubular mesh components such as an everted tubular component, an tubular component that expands to various different sizes, a bifurcated tubular component, and a tubular component with an undulating expanded shape, among others. Various components can have different densities or pore sizes and can be overlaid on each other to selectively block different regions of a vessel.
Abstract:
An inflatable, expandable implant suitable for implantation in a human body, comprising a bladder having a bladder wall defining a volume, having at least one bladder wall opening for introduction of filler material, and the bladder having no passageway through the bladder wall for passage of a body fluid from an end of the bladder to another end of the bladder, and at least one closure for each of the at least one bladder wall openings for maintaining the filler material within the volume after introduction of the filler material into the volume.