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1.发明公开PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 有权蛋白多肽合成酶IMPFSTOFFE GEGEN STREPTOCOCCUS PNEUMONIAE TYP 3
公开(公告)号：EP3046587A1
公开(公告)日：2016-07-27
申请号：EP14776605.9
申请日：2014-09-18
发明人： RATHWELL, Dominea , PARAMESWARAPPA, Sharavathi Guddehalli , GOVINDAN, Subramanian , ANISH, Chakkumkal , PEREIRA, Claney Lebev , SEEBERGER, Peter H. , BRÖCKER, Felix
CPC分类号： A61K39/092 , A61K47/54 , A61K47/543 , A61K47/545 , A61K47/549 , A61K47/55 , A61K47/61 , A61K2039/55555 , A61K2039/575 , A61K2039/6012 , A61K2039/6087
摘要： The present invention provides a protein- and peptide-free conjugate comprising a synthetic carbohydrate and a carrier molecule, wherein the synthetic carbohydrate is a Streptococcus pneumoniae type 3 capsular polysaccharide related carbohydrate and the carrier molecule is a glycosphingolipid. Said conjugate and pharmaceutical composition thereof are useful for immunization against diseases associated with Streptococcus pneumoniae , and more specifically against diseases associated with Streptococcus pneumoniae type 3.
摘要翻译： 本发明提供了含有合成碳水化合物和载体分子的蛋白质和无肽结合物，其中合成碳水化合物是肺炎链球菌3型荚膜多糖相关碳水化合物，载体分子是鞘糖脂。 所述缀合物及其药物组合物可用于针对与肺炎链球菌相关的疾病的免疫，更具体地针对与3型肺炎链球菌相关的疾病。
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2.发明授权PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 有权蛋白和无肽合成疫苗对抗链球菌肺炎3型
公开(公告)号：EP3046587B1
公开(公告)日：2018-01-31
申请号：EP14776605.9
申请日：2014-09-18
发明人： RATHWELL, Dominea , PARAMESWARAPPA, Sharavathi Guddehalli , GOVINDAN, Subramanian , ANISH, Chakkumkal , PEREIRA, Claney Lebev , SEEBERGER, Peter H. , BRÖCKER, Felix
CPC分类号： A61K39/092 , A61K47/54 , A61K47/543 , A61K47/545 , A61K47/549 , A61K47/55 , A61K47/61 , A61K2039/55555 , A61K2039/575 , A61K2039/6012 , A61K2039/6087
摘要： The present invention provides a protein- and peptide-free conjugate comprising a synthetic carbohydrate and a carrier molecule, wherein the synthetic carbohydrate is a Streptococcus pneumoniae type 3 capsular polysaccharide related carbohydrate and the carrier molecule is a glycosphingolipid. Said conjugate and pharmaceutical composition thereof are useful for immunization against diseases associated with Streptococcus pneumoniae , and more specifically against diseases associated with Streptococcus pneumoniae type 3.
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