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1.发明公开METHOD FOR DETERMINING THE CARDIO-GENERATIVE POTENTIAL OF MAMMALIAN CELLS 审中-公开VERFAHREN ZUR BESTIMMUNG DES KARDIOGENERATIVEN POTENZIALS VONSÄUGERZELLEN
公开(公告)号：EP2433125A1
公开(公告)日：2012-03-28
申请号：EP10721224.3
申请日：2010-05-20
IPC分类号： G01N33/50
CPC分类号： C12N5/0657 , A61K35/34 , C12N2501/105 , C12N2501/115 , C12N2501/15 , C12N2501/155 , C12N2501/16 , C12N2501/23 , C12N2501/734 , C12N2501/999 , C12N2506/1353 , C12Q1/6876 , C12Q1/6881 , C12Q2600/136 , C12Q2600/158 , G06F19/24
摘要： This document is related to a method for determining the cardio-generative potential of mammalian cells which comprises the assessment of a CARdiac generation Potential Index (CARPI) as a function of the quantification of the expression of genes of said cells. It also relates to a method for quantitatively assessing the modification of this cardio-generative potential and the cardiogenic potential of a treatment aiming at cellular differentiation.
摘要翻译： 本文件涉及用于确定哺乳动物细胞的心脏发生潜力的方法，其包括作为所述细胞的基因表达的定量的函数的CARdiac产生潜在指数（CARPI）的评估。 它还涉及一种定量评估这种心脏生成潜力的改变和针对细胞分化的治疗的心源性潜力的方法。
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公开(公告)号：EP3524980A1
公开(公告)日：2019-08-14
申请号：EP18208719.7
申请日：2010-05-20
IPC分类号： G01N33/50
摘要： This document is related to a method for determining the cardio-generative potential of mammalian cells which comprises the assessment of a CARdiac generation Potential Index (CARPI) as a function of the quantification of the expression of genes of said cells. It also relates to a method for quantitatively assessing the modification of this cardio-generative potential and the cardiogenic potential of a treatment aiming at cellular differentiation.
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公开(公告)号：EP2433125B1
公开(公告)日：2018-11-28
申请号：EP10721224.3
申请日：2010-05-20
IPC分类号： G01N33/50
CPC分类号： C12N5/0657 , A61K35/34 , C12N2501/105 , C12N2501/115 , C12N2501/15 , C12N2501/155 , C12N2501/16 , C12N2501/23 , C12N2501/734 , C12N2501/999 , C12N2506/1353 , C12Q1/6876 , C12Q1/6881 , C12Q2600/136 , C12Q2600/158 , G06F19/24
摘要： This document is related to a method for determining the cardio-generative potential of mammalian cells which comprises the assessment of a CARdiac generation Potential Index (CARPI) as a function of the quantification of the expression of genes of said cells. It also relates to a method for quantitatively assessing the modification of this cardio-generative potential and the cardiogenic potential of a treatment aiming at cellular differentiation.
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公开(公告)号：EP2432482A1
公开(公告)日：2012-03-28
申请号：EP10723556.6
申请日：2010-05-20
IPC分类号： A61K35/34
CPC分类号： A61K35/34
摘要： The present invention is related to a pharmaceutical composition comprising cells committed to the generation of heart tissue and at least one pharmaceutically acceptable excipient produced according to internationally recognized standards for pharmaceutical product manufacture, a process for the manufacture of such a pharmaceutical composition and a kit for the administration of said pharmaceutical composition which comprises a container containing said pharmaceutical composition.
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公开(公告)号：EP2506867B1
公开(公告)日：2014-10-08
申请号：EP10790375.9
申请日：2010-12-02
IPC分类号： A61K38/18 , A61K38/30 , A61K38/48 , A61K38/22 , A61K38/19 , A61K31/529 , A61K45/06 , A61P9/10
CPC分类号： A61K31/529 , A61K9/0019 , A61K38/18 , A61K38/1825 , A61K38/1841 , A61K38/1875 , A61K38/19 , A61K38/22 , A61K38/30 , A61K45/06 , A61K47/02 , A61K2300/00
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7.发明公开PHARMACEUTICAL COMPOSITIONS FOR THE STIMULATION OF STEM CELLS. 有权药剂师ZUSAMMENSETZUNGEN ZUR STIMULATION VON STAMMZELLEN
公开(公告)号：EP2506867A1
公开(公告)日：2012-10-10
申请号：EP10790375.9
申请日：2010-12-02
CPC分类号： A61K31/529 , A61K9/0019 , A61K38/18 , A61K38/1825 , A61K38/1841 , A61K38/1875 , A61K38/19 , A61K38/22 , A61K38/30 , A61K45/06 , A61K47/02 , A61K2300/00
摘要： The invention relates to a human or veterinary pharmaceutical composition (B) for the stimulation of stem cells, comprising at least two stem-cells-stimulating- agents and at least one pharmaceutically acceptable excipient.
摘要翻译： 本发明涉及用于刺激干细胞的人或兽用药物组合物（B），其包含至少两种干细胞刺激剂和至少一种药学上可接受的赋形剂。
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