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1.发明授权Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases 有权用于肥胖症，糖尿病，代谢综合征，神经变性疾病和线粒体功能障碍相关的疾病有关的治疗或预防疾病的药物组合物
公开(公告)号：EP1848432B1
公开(公告)日：2013-07-17
申请号：EP06715982.2
申请日：2006-02-15
发明人： YOO, Sang-Ku , PARK, Myunggyu , JO, In Geun , KWAK, Taehwan
IPC分类号： A61P3/04 , A61P3/10 , A61P3/00 , A61P1/16 , A61P9/10 , A61P29/00 , A61P27/02 , A61P9/12 , A61K31/352 , A61K31/353 , A61K31/343
CPC分类号： A61K31/352 , A61K8/498 , A61K9/0014 , A61K9/06 , A61K9/146 , A61K9/2054 , A61K31/343 , A61K31/353 , A61K31/453 , A61Q19/00
摘要： Provided is a pharmaceutical composition for the treatment and prevention of obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, comprising: a therapeutically effective amount of a compound represented by Formula I below, or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient, or any combination thereof.
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2.发明公开
公开(公告)号：EP1994168A1
公开(公告)日：2008-11-26
申请号：EP07708979.5
申请日：2007-02-15
发明人： PARK, Myung-Gyu , YOO, Sang-Ku , JO, In Geun , KWAK, Taehwan
IPC分类号： C12Q1/26
CPC分类号： C12Q1/26 , A61K31/12 , A61K31/343 , A61K38/44 , C12Y106/05002
摘要： Provided is a method capable of effectively treating various diseases associated with energy excess, such as obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, via elevation of an NAD(P)+ZNAD(P)H ratio by increasing an NAD(P)+ concentration in vivo or in vitro through use of NAD(P)H as a substrate or coenzyme by oxidoreductase such as NAD(P)H:quinone oxidoreductase (NQO1), a method of screening a drug for the same and a therapeutic drug.
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3.发明公开OBESITY AND METABOLIC SYNDROME TREATMENT WITH TANSHINONE DERIVATIVES WHICH INCREASE METABOLIC ACTIVITY 审中-公开肥胖和代谢综合征TRANSHINON衍生物用于提高代谢活力的治疗
公开(公告)号：EP1706108A1
公开(公告)日：2006-10-04
申请号：EP04808674.8
申请日：2004-12-30
发明人： KWAK, Taehwan , PARK, Myunggyu
IPC分类号： A61K31/343 , A61K36/18 , A61P3/04
CPC分类号： A61Q19/06 , A23C9/152 , A23L2/02 , A23L2/52 , A23L33/105 , A23V2002/00 , A61K8/4973 , A61K9/0095 , A61K9/2054 , A61K31/343 , A61K36/537 , A61K2300/00 , A23V2250/0606 , A23V2250/032 , A23V2250/704 , A23V2200/332 , A23V2200/328 , A23V2200/326 , A23V2250/708 , A23V2250/606 , A23V2250/5042
摘要： The present invention relates to a composition for preventing and treating metabolic syndrome, containing tanshinone derivatives as an effective ingredient. More specifically, the present invention relates to a composition for preventing and treating metabolic syndrome, containing tanshinone derivatives that exhibit superior activity in enhancing metabolic activity, as an effective ingredient.
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