专利检索 ap:("MediGene Aktiengesellschaft") AND inv:"SARTORIUS, Ute" 第 1 页

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发明公开
ALLOGENE VAKZINE ENTHALTEND EINE EIN COSTIMULATORISCHES POLYPEPTID EXPRIMIERENDE TUMORZELLE 审中-公开
标题翻译：同种异体疫苗包含共刺激表达多肽的肿瘤细胞

公开(公告)号：EP1441758A2

公开(公告)日：2004-08-04

申请号：EP02787620.0

申请日：2002-11-08

申请人： MediGene Aktiengesellschaft

发明人： NIELAND, John , BREIDENSTEIN, Claudia , SARTORIUS, Ute , MOEBIUS, Ulrich , BOGEDAIN, Christoph , DINKEL, Adelheid

IPC分类号： A61K39/00 , A61K39/39 , A61P35/00

CPC分类号： A61K39/0011 , A61K2039/5152 , A61K2039/5156 , A61K2039/55516 , A61K2039/55522 , A61K2039/55561 , A61K2039/57

摘要： The invention relates to the use of a tumor cell for producing a vaccine for the treatment or prophylaxis of tumors in patients, said tumor cell expressing a costimulatory polypeptide and said tumor cell and said patient having non-identical MHC molecules. The invention further relates to the use of a costimulatory polypeptide-expressing tumor cell for producing a vaccine for increasing the lytic activity of NK cells in the treatment or prophylaxis of a tumor in a patient that is allogenic with respect to the tumor cell.