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公开(公告)号：EP0968277A1
公开(公告)日：2000-01-05
申请号：EP98913653.6
申请日：1998-03-05
IPC分类号： C12N7/02
CPC分类号： B01D61/145 , A61K48/00 , C12N7/00 , C12N15/86 , C12N2710/10322 , C12N2710/10343 , C12N2710/10351 , C12N2750/14143 , C12N2750/14151
摘要： The invention relates to a filtration method for separating viruses of various sizes, wherein the solution containing said viruses is preferably filtered by one or several filtering membranes.
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2.发明公开
公开(公告)号：EP0888457A1
公开(公告)日：1999-01-07
申请号：EP97918009.0
申请日：1997-03-06
CPC分类号： C12N15/86 , A61K48/00 , A61K2039/51 , C12N2750/14143
摘要： The invention concerns an AAV vector with a foreign DNA coding for a protein that boosts immunogenicity of cells. The invention also concerns a vaccine containing such a vector and the use of both.
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公开(公告)号：EP0954592A1
公开(公告)日：1999-11-10
申请号：EP97930352.0
申请日：1997-06-24
CPC分类号： C12N7/00 , A61K48/00 , C07K14/005 , C12N15/86 , C12N2750/14122 , C12N2750/14143 , C12N2750/14152
摘要： The invention concerns a system comprising an AAV vector, which contains a foreigh DNA, and rep 68/78 sequences of AAV with delayed expression, these sequences being present (a) in cis or (b) in trans. The invention also concerns the use of such a system for the production of AAV vectors.
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4.发明公开ALLOGENE VAKZINE ENTHALTEND EINE EIN COSTIMULATORISCHES POLYPEPTID EXPRIMIERENDE TUMORZELLE 审中-公开同种异体疫苗包含共刺激表达多肽的肿瘤细胞
公开(公告)号：EP1441758A2
公开(公告)日：2004-08-04
申请号：EP02787620.0
申请日：2002-11-08
发明人： NIELAND, John , BREIDENSTEIN, Claudia , SARTORIUS, Ute , MOEBIUS, Ulrich , BOGEDAIN, Christoph , DINKEL, Adelheid
CPC分类号： A61K39/0011 , A61K2039/5152 , A61K2039/5156 , A61K2039/55516 , A61K2039/55522 , A61K2039/55561 , A61K2039/57
摘要： The invention relates to the use of a tumor cell for producing a vaccine for the treatment or prophylaxis of tumors in patients, said tumor cell expressing a costimulatory polypeptide and said tumor cell and said patient having non-identical MHC molecules. The invention further relates to the use of a costimulatory polypeptide-expressing tumor cell for producing a vaccine for increasing the lytic activity of NK cells in the treatment or prophylaxis of a tumor in a patient that is allogenic with respect to the tumor cell.
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5.发明公开
公开(公告)号：EP0891429A2
公开(公告)日：1999-01-20
申请号：EP97918010.0
申请日：1997-03-06
IPC分类号： C12N15 , A61K31 , A61K38 , A61K48 , A61K49 , A61P7 , A61P25 , A61P31 , A61P35 , A61P37 , A61P43 , C07K14 , C12N5 , C12R1
CPC分类号： C12N15/86 , C12N2750/14143
摘要： The present invention concerns a transduction system comprising (a) a rep-negative AAV vector containing a foreign DNA and (b) an agent for preparing an AAV rep-protein. The invention also relates to the use of the transduction system.
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