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公开(公告)号：EP4065567B1
公开(公告)日：2024-09-11
申请号：EP20824397.2
申请日：2020-11-20
IPC分类号： C07D267/16 , C07C381/10 , C07D513/08 , C07D513/10 , C07D515/20 , C07C43/178 , C07C69/63 , C07C205/59 , C07C229/64 , C07C309/20 , C07C311/11 , C07F7/18
CPC分类号： C07D513/08 , C07D513/10 , C07D515/20 , C07D267/16 , C07C381/10 , C07C43/1781 , C07C2601/0420170501 , C07C69/63 , C07C2602/1020170501 , C07F7/1804 , C07C205/59 , C07C229/64 , C07C311/11 , C07C309/20
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公开(公告)号：EP4441054A1
公开(公告)日：2024-10-09
申请号：EP22823521.4
申请日：2022-11-30
发明人： BROEKER, Joachim , ABBOTT, Jason , CUI, Jianwen , FESIK, Stephen W. , FUCHS, Julian , GOLLNER, Andreas , HERDEIS, Lorenz , HODGES, Tim , LITTLE, Andrew , MANTOULIDIS, Andreas , PHAN, Jason , SARKAR, Dhruba , SMETHURST, Christian Alan Paul , SUN, Qi , WATERSON, Alex
IPC分类号： C07D498/10 , C07D515/20 , A61K31/513 , A61K31/541 , A61K31/551 , A61P35/00
CPC分类号： C07D498/10 , C07D515/20 , A61K31/5513 , A61K31/506 , A61K45/06
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3.发明授权TETRASUBSTITUIERTE OXATHIAZINDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, IHRE VERWENDUNG ALS MEDIKAMENT SOWIE SIE ENTHALTENDES ARZNEIMITTEL UND DEREN VERWENDUNG 有权TETRA的取代的OXATHIAZINDERIVATE，制造工艺及其作为药物和含有药物及其用途
公开(公告)号：EP2683700B1
公开(公告)日：2015-02-18
申请号：EP12707596.8
申请日：2012-03-07
申请人： SANOFI
发明人： BOEHME, Thomas , ENGEL, Christian , GUESSREGEN, Stefan , HAACK, Torsten , RITTER, Kurt , TSCHANK, Georg
IPC分类号： C07D291/06 , A61K31/54 , A61P3/10 , C07D291/02 , C07D419/12 , C07D515/10
CPC分类号： C07D291/06 , A61K31/54 , A61K31/541 , A61K31/547 , A61K45/06 , C07D291/02 , C07D291/08 , C07D419/12 , C07D515/10 , C07D515/20
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公开(公告)号：EP2433940B9
公开(公告)日：2015-10-28
申请号：EP10769728.6
申请日：2010-04-27
发明人： ESAKI, Toru , NISHIMURA, Yoshikazu , ISSHIKI, Yoshiaki , OKAMOTO, Naoki , FURUTA, Yoshiyuki , MIZUTANI, Akemi , OHTA, Masateru , LAI, Wayne Wen , KOTAKE, Tomoya
IPC分类号： C07D471/10 , A61K31/438 , A61K31/444 , A61K31/496 , A61K31/5355 , A61P5/20 , A61P7/08 , A61P19/02 , A61P19/08 , A61P43/00 , C07D487/10
CPC分类号： C07D471/10 , C07D471/20 , C07D491/107 , C07D513/20 , C07D513/22 , C07D515/20
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5.发明公开TETRASUBSTITUIERTE OXATHIAZINDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, IHRE VERWENDUNG ALS MEDIKAMENT SOWIE SIE ENTHALTENDES ARZNEIMITTEL UND DEREN VERWENDUNG 有权TETRA的取代的OXATHIAZINDERIVATE，制造工艺及其作为药物和含有药物及其用途
公开(公告)号：EP2683700A1
公开(公告)日：2014-01-15
申请号：EP12707596.8
申请日：2012-03-07
申请人： SANOFI
发明人： BOEHME, Thomas , ENGEL, Christian , GUESSREGEN, Stefan , HAACK, Torsten , RITTER, Kurt , TSCHANK, Georg
IPC分类号： C07D291/06 , A61K31/54 , A61P3/10 , C07D291/02 , C07D419/12 , C07D515/10
CPC分类号： C07D291/06 , A61K31/54 , A61K31/541 , A61K31/547 , A61K45/06 , C07D291/02 , C07D291/08 , C07D419/12 , C07D515/10 , C07D515/20
摘要： The invention relates to the compounds of formula (I) and to the physiologically acceptable salts thereof. Said compounds are suitable e.g. for the treatment of hyperglycemia.
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公开(公告)号：EP4364804A3
公开(公告)日：2024-09-04
申请号：EP24151840.6
申请日：2019-08-19
发明人： CHAI, Wenying , HIRST, Gavin C. , KREUTTER, Kevin D. , KUMMER, David A. , MCCLURE, Kelly J. , NISHIMURA, Rachel T. , SHIH, Amy Y. , VENABLE, Jennifer D. , VENKATESAN, Hariharan , WEI, Jianmei , BARBAY, J. Kent
IPC分类号： C07D417/10 , C07D417/14 , C07D419/10 , C07D419/14 , C07D471/04 , C07D487/04 , C07D513/04 , C07D513/14 , C07D515/04 , C07D515/14 , A61K31/554 , A61P3/00 , A61P11/00 , A61P9/00 , A61P29/00
CPC分类号： A61K31/554 , C07D417/10 , C07D417/14 , C07D419/10 , C07D419/14 , C07D471/04 , C07D487/04 , C07D513/04 , C07D513/14 , C07D515/04 , C07D515/14 , C07D513/10 , C07D515/10 , C07D515/20 , C07D519/00
摘要： Sultam compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with the KEAP1-Nrf2 interaction, such as inflammatory bowel disease, including Crohn's disease and ulcerative colitis.
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7.发明授权SPIRO-CONDENSED 1, 3, 4-THIADIAZOLE DERIVATIVES FOR INHIBITING KSP KINESIN ACTIVITY 有权螺稠-1,3,4-噻二唑用于抑制KSP驱动蛋白活性
公开(公告)号：EP2220061B1
公开(公告)日：2016-02-17
申请号：EP08839917.5
申请日：2008-10-16
发明人： SIDDIQUI, M. Arshad , DAI, Chaoyang , MANSOOR, Umar, Faruk , YANG, Liping , VITHARANA, Lalalnthi, Dilrukshi , ANGELES, Angie, R.
IPC分类号： C07D285/14 , C07D515/10 , C07D515/20 , A61K31/433 , A61P35/00
CPC分类号： C07D211/14 , C07D285/14 , C07D471/04 , C07D515/10 , C07D515/20
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公开(公告)号：EP2433940B1
公开(公告)日：2014-09-24
申请号：EP10769728.6
申请日：2010-04-27
发明人： ESAKI, Toru , NISHIMURA, Yoshikazu , ISSHIKI, Yoshiaki , OKAMOTO, Naoki , FURUTA, Yoshiyuki , MIZUTANI, Akemi , OHTA, Masateru , LAI, Wayne Wen , KOTAKE, Tomoya
IPC分类号： C07D471/10 , A61K31/438 , A61K31/444 , A61K31/496 , A61K31/5355 , A61P5/20 , A61P7/08 , A61P19/02 , A61P19/08 , A61P43/00 , C07D487/10
CPC分类号： C07D471/10 , C07D471/20 , C07D491/107 , C07D513/20 , C07D513/22 , C07D515/20
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公开(公告)号：EP4364804A2
公开(公告)日：2024-05-08
申请号：EP24151840.6
申请日：2019-08-19
发明人： CHAI, Wenying , HIRST, Gavin C. , KREUTTER, Kevin D. , KUMMER, David A. , MCCLURE, Kelly J. , NISHIMURA, Rachel T. , SHIH, Amy Y. , VENABLE, Jennifer D. , VENKATESAN, Hariharan , WEI, Jianmei , BARBAY, J. Kent
IPC分类号： A61P29/00
CPC分类号： A61K31/554 , C07D417/10 , C07D417/14 , C07D419/10 , C07D419/14 , C07D471/04 , C07D487/04 , C07D513/04 , C07D513/14 , C07D515/04 , C07D515/14 , C07D513/10 , C07D515/10 , C07D515/20 , C07D519/00
摘要： Sultam compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with the KEAP1-Nrf2 interaction, such as inflammatory bowel disease, including Crohn's disease and ulcerative colitis.
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10.发明公开CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B 审中-公开环状磺胺酰基酰胺衍生物及其用作治疗乙型肝炎的药物
公开(公告)号：EP3317286A1
公开(公告)日：2018-05-09
申请号：EP16733102.4
申请日：2016-07-01
发明人： VENDEVILLE, Sandrine, Marie, Helene , LAST, Stefaan, Julien , DEMIN, Samuël, Dominique , GROSSE, Sandrine, Céline , HACHÉ, Geerwin, Yvonne, Paul , HU, Lili , PIETERS, Serge, Maria, Aloysius , ROMBOUTS, Geert , VANDYCK, Koen , VERSCHUEREN, Wim, Gaston , RABOISSON, Pierre, Jean-Marie, Bernard
IPC分类号： C07D513/04 , C07D515/04 , C07D291/08 , C07D515/20 , C07D513/20 , A61K31/407 , A61P31/20
CPC分类号： C07D513/04 , A61K31/407 , A61K31/542 , A61K31/554 , A61K45/06 , C07D291/08 , C07D513/20 , C07D515/04 , C07D515/10 , C07D515/20 , A61K2300/00
摘要： The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
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