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1.发明授权
公开(公告)号：EP3393472B1
公开(公告)日：2020-08-12
申请号：EP16879916.1
申请日：2016-12-19
发明人： ACTON, John, J., III , BAO, Jianming , EGBERTSON, Melissa , GAO, Xiaolei , HARRISON, Scott T. , KNOWLES, Sandra L. , LI, Chunsing , LO, Michael Man-Chu , MAZZOLA, Robert D., Jr. , MENG, Zhaoyang , RUDD, Michael, T. , SELYUTIN, Oleg , TELLERS, David, M. , TONG, Ling , WAI, Jenny Miu-Chun
IPC分类号： A61K31/4155 , C07D231/10
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2.发明公开
公开(公告)号：EP3644992A1
公开(公告)日：2020-05-06
申请号：EP18825469.2
申请日：2018-06-22
发明人： ACTON, John, J., III , BAO, Jianming , DENG, Qiaolin , EGBERTSON, Melissa , FERGUSON, Ronald, III , GAO, Xiaolei , HARRISON, Scott Timothy , KNOWLES, Sandra L. , LI, Chunsing , LO, Michael Man-Chu , MAZZOLA, Robert D., Jr. , MENG, Zhaoyang , NA, Meng , RUDD, Michael T. , SELYUTIN, Oleg B. , TELLERS, David M. , TONG, Ling , ZHANG, Fengqi
IPC分类号： A61K31/4155 , C07D231/10
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3.发明公开
公开(公告)号：EP3393472A1
公开(公告)日：2018-10-31
申请号：EP16879916.1
申请日：2016-12-19
发明人： ACTON, John, J., III , BAO, Jianming , EGBERTSON, Melissa , GAO, Xiaolei , HARRISON, Scott T. , KNOWLES, Sandra L. , LI, Chunsing , LO, Michael Man-Chu , MAZZOLA, Robert D., Jr. , MENG, Zhaoyang , RUDD, Michael, T. , SELYUTIN, Oleg , TELLERS, David, M. , TONG, Ling , WAI, Jenny Miu-Chun
IPC分类号： A61K31/4155 , C07D231/10
摘要： The present invention is directed to pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.
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