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公开(公告)号：EP2882754A1
公开(公告)日：2015-06-17
申请号：EP13748245.1
申请日：2013-08-06
发明人： BARA, Thomas , BHAT, Sathesh , BISWAS, Dipshika , BROCKUNIER, Linda , BURNETTE, Duane , CHACKALAMANNIL, Samuel , CHELIAH, Mariappan, V. , CHEN, Austin , CLASBY, Martin , COLANDREA, Vince, J. , GUO, Zhuyan , HAN, Yongxin , JAYNE, Charles , JOSIEN, Hubert , MARCANTONIO, Karen , MIAO, Shouwu , NEELAMKAVIL, Santhosh , PINTO, Patrick , RAJAGOPALAN, Murali , SHAH, Unmesh , VELAZQUEZ, Francisco , VENKATRAMAN, Srikanth , XIA, Yan
IPC分类号： C07D491/107 , A61K31/343 , A61K31/407 , A61P1/16 , A61P31/14
CPC分类号： C07K5/08 , A61K38/06 , A61K45/06 , C07D419/00 , C07D491/22
摘要： The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.
摘要翻译： 本发明涉及含有螺环状的丙型肝炎病毒（HCV）NS3蛋白酶抑制剂，这些化合物的用途以及这些化合物的合成。
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公开(公告)号：EP2882754B1
公开(公告)日：2018-10-03
申请号：EP13748245.1
申请日：2013-08-06
发明人： BARA, Thomas , BHAT, Sathesh , BISWAS, Dipshika , BROCKUNIER, Linda , BURNETTE, Duane , CHACKALAMANNIL, Samuel , CHELIAH, Mariappan, V. , CHEN, Austin , CLASBY, Martin , COLANDREA, Vince, J. , GUO, Zhuyan , HAN, Yongxin , JAYNE, Charles , JOSIEN, Hubert , MARCANTONIO, Karen , MIAO, Shouwu , NEELAMKAVIL, Santhosh , PINTO, Patrick , RAJAGOPALAN, Murali , SHAH, Unmesh , VELAZQUEZ, Francisco , VENKATRAMAN, Srikanth , XIA, Yan
IPC分类号： C07D491/22 , C07D419/00 , A61K45/06 , A61K31/343 , A61K31/407 , A61P1/16 , A61P31/14
CPC分类号： C07K5/08 , A61K38/06 , A61K45/06 , C07D419/00 , C07D491/22
摘要： The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.
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公开(公告)号：EP3463362A1
公开(公告)日：2019-04-10
申请号：EP17803324.7
申请日：2017-05-19
发明人： ADAMS, Gregory, L. , COX, Jason, M. , DEBENHAM, John, S. , EDMONDSON, Scott , GILBERT, Eric, J. , GUO, Yan , JIANG, Yu , JOSIEN, Hubert , KIM, Hyunjin, M. , LAN, Ping , MIAO, Shouwu , PLUMMER, Christopher, W. , RAJAGOPALAN, Murali , SHAH, Unmesh , SUN, Zhongxiang , TRUONG, Quang, T. , UJJAINWALLA, Feroze , VELAZQUEZ, Francisco , VENKATRAMAN, Srikanth , SUZUKI, Takao , WANG, Nengxue
IPC分类号： A61K31/472 , A61K31/4725 , A61P3/10 , C07D217/02
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4.发明授权CARBOCYCLIC AND HETEROCYCLIC ARYLSULFONES AS GAMMA SECRETASE INHIBITORS 有权CARBOCYCLISCHE UND HETEROCYCLISCHE ARYLSULFONE ALS GAMMA-SEKRETASE-HEMMER
公开(公告)号：EP1976843B1
公开(公告)日：2013-09-04
申请号：EP07716750.0
申请日：2007-01-18
发明人： ASBEROM, Theodros , BARA, Thomas , BENNETT, Chad, E. , BURNETT, Duane, A. , CAPLEN, Mary Ann , CLADER, John, W. , COLE, David, J. , DOMALSKI, Martin, S. , JOSIEN, Hubert, B. , KNUTSON, Chad, E. , LI, Hongmei , MCBRIAR, Mark, D. , PISSARNITSKI, Dmitri, A. , QIANG, Li , RAJAGOPALAN, Murali , SASIKUMAR, Thavalakulamgar, K. , SU, Jing , TANG, Haiqun , WU, Wen-Lian , XU, Ruo , ZHAO, Zhiqiang
IPC分类号： C07D311/22 , C07D311/80 , C07D311/92 , C07D311/94 , C07D313/08 , C07D335/06
CPC分类号： C07D311/22 , C07C317/14 , C07C317/20 , C07C317/44 , C07C2602/08 , C07C2602/10 , C07C2602/12 , C07D311/80 , C07D311/92 , C07D311/94 , C07D313/08 , C07D335/06 , C07D405/12 , C07D409/12 , C07D491/04 , C07D493/04
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