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公开(公告)号：EP2227334A2
公开(公告)日：2010-09-15
申请号：EP08858277.0
申请日：2008-12-08
申请人： Miltenyi Biotec GmbH
发明人： MILTENYI, Stefan , SCHIMMELPFENNIG, Winfried , LANTOW, Holger , NEUSCHÄFER, Elmar, Niklas , BIEHL, Martin , KABAHA, Eiad , SCHULZ, Jürgen
CPC分类号： G01N33/58 , A61M1/0209 , A61M1/3618 , A61M1/3633 , A61M1/3679 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2202/0071 , A61M2202/0413 , A61M2202/0427 , A61M2202/10 , B01D15/3809 , B01D15/3885 , B01D21/26 , B03C1/002 , B03C1/027 , B03C1/032 , B03C1/0332 , B03C1/0335 , B03C1/034 , B03C1/288 , B03C2201/18 , B03C2201/26 , B04B1/12 , B04B5/00 , B04B5/04 , B04B5/0442 , B04B5/10 , B04B7/08 , B04B13/00 , B04B2005/0464 , B04B2013/006 , C12M23/28 , C12M33/10 , C12M41/48 , C12M47/04 , C12N5/0636 , C12N5/0646 , C12N5/0647 , C12N5/0669 , G01N35/0098 , G01N2333/70596
摘要： The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder, a pump and a plurality of valves configured to at least partially control fluid flow through a fluid circuitry and a separation column positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
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公开(公告)号：EP2227271B1
公开(公告)日：2018-01-24
申请号：EP08857318.3
申请日：2008-12-08
申请人： Miltenyi Biotec GmbH
发明人： MILTENYI, Stefan , SCHIMMELPFENNIG, Winfried , LANTOW, Holger , NEUSCHÄFER, Elmar, Niklas , BIEHL, Martin , KABAHA, Eiad , SCHULZ, Jürgen
CPC分类号： G01N33/58 , A61M1/0209 , A61M1/3618 , A61M1/3633 , A61M1/3679 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2202/0071 , A61M2202/0413 , A61M2202/0427 , A61M2202/10 , B01D15/3809 , B01D15/3885 , B01D21/26 , B03C1/002 , B03C1/027 , B03C1/032 , B03C1/0332 , B03C1/0335 , B03C1/034 , B03C1/288 , B03C2201/18 , B03C2201/26 , B04B1/12 , B04B5/00 , B04B5/04 , B04B5/0442 , B04B5/10 , B04B7/08 , B04B13/00 , B04B2005/0464 , B04B2013/006 , C12M23/28 , C12M33/10 , C12M41/48 , C12M47/04 , C12N5/0636 , C12N5/0646 , C12N5/0647 , C12N5/0669 , G01N35/0098 , G01N2333/70596
摘要： The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder, a pump and a plurality of valves configured to at least partially control fluid flow through a fluid circuitry and a separation column positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
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公开(公告)号：EP2227271A2
公开(公告)日：2010-09-15
申请号：EP08857318.3
申请日：2008-12-08
申请人： Miltenyi Biotec GmbH
发明人： MILTENYI, Stefan , SCHIMMELPFENNIG, Winfried , LANTOW, Holger , NEUSCHÄFER, Elmar, Niklas , BIEHL, Martin , KABAHA, Eiad , SCHULZ, Jürgen
CPC分类号： G01N33/58 , A61M1/0209 , A61M1/3618 , A61M1/3633 , A61M1/3679 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2202/0071 , A61M2202/0413 , A61M2202/0427 , A61M2202/10 , B01D15/3809 , B01D15/3885 , B01D21/26 , B03C1/002 , B03C1/027 , B03C1/032 , B03C1/0332 , B03C1/0335 , B03C1/034 , B03C1/288 , B03C2201/18 , B03C2201/26 , B04B1/12 , B04B5/00 , B04B5/04 , B04B5/0442 , B04B5/10 , B04B7/08 , B04B13/00 , B04B2005/0464 , B04B2013/006 , C12M23/28 , C12M33/10 , C12M41/48 , C12M47/04 , C12N5/0636 , C12N5/0646 , C12N5/0647 , C12N5/0669 , G01N35/0098 , G01N2333/70596
摘要： The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder, a pump and a plurality of valves configured to at least partially control fluid flow through a fluid circuitry and a separation column positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
摘要翻译： 本发明涉及一种系统，包括：a）样品处理单元，包括输入端口和耦合到具有至少一个样品室的旋转容器的输出端口，所述样品处理单元配置为样品提供第一处理步骤， 使容器旋转以对沉积在室中的样品施加离心力，并分离沉积样品的至少第一组分和第二组分; 以及b）样品分离单元，其耦合到所述样品处理单元的输出端口，所述细胞分离单元包括分离柱保持器，泵和多个阀，所述多个阀构造成至少部分地控制通过流体回路的流体流和分离柱 定位在保持器中，分离柱构造成分离流过柱的样品的标记和未标记组分。
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4.发明授权A CENTRIFUGE FOR SEPARATING A SAMPLE INTO AT LEAST TWO COMPONENTS 有权ZENTRIFUGE ZUR TRENNUNG EINER MINIESTENS探索ZWEI KOMPONENTEN
公开(公告)号：EP2227334B1
公开(公告)日：2011-10-12
申请号：EP08858277.0
申请日：2008-12-08
申请人： Miltenyi Biotec GmbH
发明人： MILTENYI, Stefan , SCHIMMELPFENNIG, Winfried , LANTOW, Holger , NEUSCHÄFER, Elmar, Niklas , BIEHL, Martin , KABAHA, Eiad , SCHULZ, Jürgen
CPC分类号： G01N33/58 , A61M1/0209 , A61M1/3618 , A61M1/3633 , A61M1/3679 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2202/0071 , A61M2202/0413 , A61M2202/0427 , A61M2202/10 , B01D15/3809 , B01D15/3885 , B01D21/26 , B03C1/002 , B03C1/027 , B03C1/032 , B03C1/0332 , B03C1/0335 , B03C1/034 , B03C1/288 , B03C2201/18 , B03C2201/26 , B04B1/12 , B04B5/00 , B04B5/04 , B04B5/0442 , B04B5/10 , B04B7/08 , B04B13/00 , B04B2005/0464 , B04B2013/006 , C12M23/28 , C12M33/10 , C12M41/48 , C12M47/04 , C12N5/0636 , C12N5/0646 , C12N5/0647 , C12N5/0669 , G01N35/0098 , G01N2333/70596
摘要： The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder, a pump and a plurality of valves configured to at least partially control fluid flow through a fluid circuitry and a separation column positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
摘要翻译： 本发明涉及一种系统，包括：a）样品处理单元，包括输入端口和耦合到具有至少一个样品室的旋转容器的输出端口，所述样品处理单元配置为样品提供第一处理步骤， 使容器旋转以对沉积在室中的样品施加离心力，并分离沉积样品的至少第一组分和第二组分; 以及b）样品分离单元，其耦合到所述样品处理单元的输出端口，所述细胞分离单元包括分离柱保持器，泵和多个阀，所述多个阀构造成至少部分地控制通过流体回路的流体流和分离柱 定位在保持器中，分离柱构造成分离流过柱的样品的标记和未标记组分。
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