-
公开(公告)号：EP4232091A1
公开(公告)日：2023-08-30
申请号：EP21884148.4
申请日：2021-10-26
发明人： TREVASKIS, Natalie , PORTER, Christopher John , LEE, Given , HAN, Sifei , PHILLIPS, Anthony , WINDSOR, John , HONG, Jiwon , STYLES, Ian Kenneth , LU, Zijun
IPC分类号： A61K47/12 , A61K31/365 , A61P1/18
-
公开(公告)号：EP4306524A2
公开(公告)日：2024-01-17
申请号：EP23193733.5
申请日：2018-08-29
发明人： BONNER, Daniel Kenneth , HAN, Sifei , HU, Luojuan , KARANAM, Ketki , MUTAMBA, James T. , PORTER, Christopher John Hamilton , SHYAM, Rishab R. , SIMPSON, Jamie , TREVASKIS, Natalie , QUACH, Tim
IPC分类号： C07D473/34
摘要： The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.
-
公开(公告)号：EP3347340A1
公开(公告)日：2018-07-18
申请号：EP16843301.9
申请日：2016-09-08
申请人： Monash University
发明人： PORTER, Chris , SIMPSON, Jamie , TREVASKIS, Natalie , QUACH, Tim , HAN, Sifei , HU, Luojuan
IPC分类号： C07C219/08 , C07C271/24 , C07C233/14 , C07D307/88 , C07D489/12 , C07J1/00 , A61K31/568 , A61K31/485 , A61K31/365 , A61K31/27 , A61K31/165 , A61K31/222
CPC分类号： A61K47/542 , A61K9/0053 , A61K31/138 , A61K31/165 , A61K31/167 , A61K31/222 , A61K31/27 , A61K31/365 , A61K31/485 , A61K31/568 , A61K45/06 , C07C219/06 , C07C235/36 , C07C271/24 , C07C2602/26 , C07D307/88 , C07D489/12 , C07J1/0025 , C07J1/0029
摘要： The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that pro mote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.
-
公开(公告)号：EP4100017A1
公开(公告)日：2022-12-14
申请号：EP21750039.6
申请日：2021-02-05
-
公开(公告)号：EP3829590A1
公开(公告)日：2021-06-09
申请号：EP19844792.2
申请日：2019-08-02
发明人： BONNER, Daniel Kenneth , KARANAM, Ketki , SIMPSON, Jamie , PORTER, Christopher John , TREVASKIS, Natalie , QUACH, Tim , HAN, Sifei , HU, Luojuan
IPC分类号： A61K31/57
-
公开(公告)号：EP3675838A1
公开(公告)日：2020-07-08
申请号：EP18851922.7
申请日：2018-08-29
发明人： BONNER, Daniel Kenneth , KARANAM, Ketki , MUTAMBA, James T. , SHYAM, Rishab R. , SIMPSON, Jamie , HAN, Sifei , HU, Luojuan , PORTER, Christopher John Hamilton , QUACH, Tim , TREVASKIS, Natalie
IPC分类号： A61K31/015 , A61K31/495 , A61K31/4985 , C07C13/12 , C07D473/32 , C07D473/34
-
公开(公告)号：EP4306524A3
公开(公告)日：2024-09-11
申请号：EP23193733.5
申请日：2018-08-29
发明人： BONNER, Daniel Kenneth , HAN, Sifei , HU, Luojuan , KARANAM, Ketki , MUTAMBA, James T. , PORTER, Christopher John Hamilton , SHYAM, Rishab R. , SIMPSON, Jamie , TREVASKIS, Natalie , QUACH, Tim
IPC分类号： A61K31/015 , A61K31/495 , A61K31/4985 , C07C13/12 , C07D473/32 , C07D473/34 , A61K45/06 , A61K47/54 , C07C69/34 , C07C69/40 , C07C69/42 , C07C69/58 , C07C69/708 , C07C69/96 , C07C233/25 , C07C235/74 , C07C271/24 , C07D311/80 , C07D307/88 , C07D409/12 , C07D489/02
CPC分类号： A61K45/06 , A61K47/543 , C07B2200/0720130101 , C07C69/34 , C07C69/40 , C07C69/42 , C07C69/58 , C07C69/708 , C07C69/96 , C07C233/25 , C07C235/74 , C07C271/24 , C07C2601/1620170501 , C07C2602/0820170501 , C07C2602/1020170501 , C07C2603/4020170501 , C07D307/88 , C07D311/80 , C07D409/12 , C07D489/02 , C07D498/18 , A61K47/542 , A61P37/02 , C07C13/12 , C07D209/08 , C07D333/56 , Y02A50/30
摘要： The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.
-
公开(公告)号：EP3930709A1
公开(公告)日：2022-01-05
申请号：EP20762421.4
申请日：2020-02-28
发明人： BOLEN, Joseph , BONNER, Daniel Kenneth , KARANAM, Ketki , PORTER, Christopher John , SIMPSON, Jamie , TREVASKIS, Natalie , ZHENG, Dan , LEONG, Nathania , SHARMA, Garima , MCINERNEY, Mitchell , QUACH, Tim , HAN, Sifei
IPC分类号： A61K31/407 , C07D487/02 , C07D487/04
-
公开(公告)号：EP3727362A1
公开(公告)日：2020-10-28
申请号：EP18890811.5
申请日：2018-12-19
发明人： BONNER, Daniel Kenneth , KARANAM, Ketki , HAN, Sifei , HU, Luojuan , PORTER, Christopher John Hamilton , QUACH, Tim , SHYAM, Rishab R. , SIMPSON, Jamie , TREVASKIS, Natalie
IPC分类号： A61K31/138 , A61K31/167 , A61K31/27
-
公开(公告)号：EP3180349A1
公开(公告)日：2017-06-21
申请号：EP15832378.2
申请日：2015-08-12
申请人： Monash University
发明人： PORTER, Chris , SIMPSON, Jamie , TREVASKIS, Natalie , QUACH, Tim , HAN, Sifei , HU, Luojuan
CPC分类号： A61K31/365 , A61K31/40 , A61K31/4025 , A61K31/568 , A61K45/06 , A61P5/24 , C07J1/0025 , C07J1/0029 , C07J5/00 , C07J7/002 , C07J9/00 , C07J31/00 , C07J31/006 , G01N30/48 , G01N2030/486 , A61K2300/00
摘要： The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that promote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.
摘要翻译： 本发明涉及化合物及其用途，特别是前体药物形式的化合物，其促进药剂向 淋巴系统并随后增强母体药物的释放。
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.012 秒)
