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公开(公告)号:EP4397665A3
公开(公告)日:2024-08-21
申请号:EP24158643.7
申请日:2016-07-05
发明人: CUI, Jingrong J. , ROGERS, Evan W.
IPC分类号: C07D491/16 , A61K31/519 , A61K31/52 , C07D491/12 , C07D491/18 , C07D498/18
CPC分类号: C07C271/16 , C07B2200/0720130101 , C07D498/18 , A61P35/00 , Y02P20/55
摘要: This disclosure relates to polymorphs of (7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotiidecin-4(5H)-one that are useful in the treatment of disease, such as cancer, in mammals. This disclosure also relates to compositions including such polymorphs, and to methods of using such compositions in the treatment of diseases, such as cancer, in mammals, especially in humans.
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2.
公开(公告)号:EP4412973A1
公开(公告)日:2024-08-14
申请号:EP22785756.2
申请日:2022-10-04
申请人: Givaudan SA
发明人: LINIGER, Marc
IPC分类号: C07C31/125 , C07C33/025 , C07C33/05 , C07C47/21 , C11B9/00
CPC分类号: C07C47/21 , C11B9/00 , C07B2200/0720130101 , C07C33/025 , C07C33/05 , C07C31/125 , C07C2601/0220170501
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公开(公告)号:EP4397665A2
公开(公告)日:2024-07-10
申请号:EP24158643.7
申请日:2016-07-05
发明人: CUI, Jingrong J. , ROGERS, Evan W.
IPC分类号: C07D498/18
CPC分类号: C07C271/16 , C07B2200/0720130101 , C07D498/18 , A61P35/00 , Y02P20/55
摘要: This disclosure relates to polymorphs of (7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotiidecin-4(5H)-one that are useful in the treatment of disease, such as cancer, in mammals. This disclosure also relates to compositions including such polymorphs, and to methods of using such compositions in the treatment of diseases, such as cancer, in mammals, especially in humans.
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公开(公告)号:EP4396160A1
公开(公告)日:2024-07-10
申请号:EP22764434.1
申请日:2022-08-30
IPC分类号: C07C219/06 , C07F7/18
CPC分类号: C07C219/06 , C07B2200/0720130101 , C07F7/1804
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公开(公告)号:EP4430023A1
公开(公告)日:2024-09-18
申请号:EP22891241.6
申请日:2022-11-10
IPC分类号: C07C229/08 , A61K47/55 , A61P25/00 , C07C229/28 , C07C271/48 , C07C271/54
CPC分类号: A61K47/55 , A61P25/00 , C07C229/08 , C07C229/28 , C07C271/48 , C07C271/54 , C07C2601/1420170501 , C07C2601/1620170501 , C07B2200/0720130101 , C07C305/24
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公开(公告)号:EP4424677A1
公开(公告)日:2024-09-04
申请号:EP23159988.7
申请日:2023-03-03
申请人: RDP Pharma AG
发明人: CHANG, Cheng-Hao , WANG, Yu Fa , MARTI, Roger , MYLÈNE, Soudani , CRISP, Antony
IPC分类号: C07D303/32 , C07F9/113 , C07C43/315 , C07F9/10
CPC分类号: C07F9/10 , C07B2200/0720130101 , C07F9/113 , C07D303/32 , C07C43/315
摘要: The present invention relates to an improved method for the synthesis of (S) or (R)-edelfosine ((S) or (R)-CP201).
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公开(公告)号:EP4410989A2
公开(公告)日:2024-08-07
申请号:EP24184274.9
申请日:2020-06-10
发明人: UCHIDA, Hideharu , SATOH, Tsutomu , SUN, Baoquan , SHA, Chunbo , LIN, Jinguang , GE, Yonghui , CHEN, Yanliang , ZHAO, Bin , GU, Xiaomin , LUO, Jian , CHEN, Chuan , CAI, Xiaofei , YE, Jiajie , LI, Jie , SUN, Fenglai
IPC分类号: C12P7/02
CPC分类号: C07D311/58 , C07C35/52 , C07C2602/1020170501 , C07B2200/0720130101 , C07C213/02 , C12P17/06 , C12Y101/01 , C07B53/00 , C07B61/00 , C07C29/143 , C07C209/10 , C07C215/70 , C12P7/02
摘要: The present invention provides, a novel method for producing a compound represented by formula (I) and a novel method for producing a compound represented by formula (B) or a salt thereof, which are intermediates in the production of formula (I).
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公开(公告)号:EP4019485B1
公开(公告)日:2024-08-07
申请号:EP20859098.4
申请日:2020-06-10
IPC分类号: C07B53/00 , C07C29/143 , C07C35/52 , C07C209/10 , C07C215/70 , C07D311/58 , C07B61/00 , C12P7/02
CPC分类号: C07D311/58 , C07C35/52 , C07C2602/1020170501 , C07B2200/0720130101 , C07C213/02 , C12P17/06 , C12Y101/01 , C07B53/00 , C07B61/00 , C07C29/143 , C07C209/10 , C07C215/70 , C12P7/02
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公开(公告)号:EP4405041A1
公开(公告)日:2024-07-31
申请号:EP22793143.3
申请日:2022-09-23
申请人: Atrogi AB
发明人: BENGTSSON, Tore , PELCMAN, Benjamin
IPC分类号: A61P3/10 , C07C53/10 , C07C215/30 , C07C215/42 , C07C217/52 , C07C229/46 , C07C233/41 , C07C233/62 , C07C233/79 , C07C255/46 , C07C271/24 , C07C275/26 , C07C311/07 , C07D213/38 , C07D213/61 , C07D213/84
CPC分类号: C07C217/52 , C07D213/61 , C07C215/42 , C07C233/41 , C07C233/79 , C07C311/07 , C07C215/30 , C07C229/46 , C07C53/10 , C07C255/46 , C07D213/84 , C07D213/38 , C07C271/24 , C07C233/62 , C07C275/26 , A61P3/10 , C07C2601/1420170501 , C07B2200/0720130101
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10.
公开(公告)号:EP3574908B1
公开(公告)日:2024-07-31
申请号:EP19167006.6
申请日:2012-05-14
IPC分类号: C07C309/04 , C07C239/20 , A61P17/00 , A61P17/10 , A61P31/04
CPC分类号: C07C239/20 , C07B2200/0720130101 , C07B2200/1320130101 , C07C2603/4620170501 , C07C309/04 , A61P17/00 , A61P17/10 , A61P31/04
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