专利检索 ap:("NantBio, Inc." OR "NantOmics, LLC" OR "Nant Holdings IP, LLC") AND inv:"KAYVAN, Niazi" 第 1 页

1.

发明授权
COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS 有权

公开(公告)号：EP3277678B1

公开(公告)日：2020-03-18

申请号：EP16774366.5

申请日：2016-04-01

申请人： NantBio, Inc. , NantOmics, LLC , Nant Holdings IP, LLC

发明人： RABIZADEH, Shahrooz , KAYVAN, Niazi , BUZKO, Oleksandr V. , WEINGARTEN, Paul , MCFARLANE, Heather , JUNCKER-JENSEN, Anna , GOLOVATO, Justin , SOON-SHIONG, Patrick , TAO, Chunlin , HO, David

IPC分类号： C07D417/12 , C07D417/14 , A61K31/427 , A61K31/4725 , A61P35/00

2.

发明公开
COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS 审中-公开
标题翻译：靶向突变K-RAS的组合物和方法

公开(公告)号：EP3277678A1

公开(公告)日：2018-02-07

申请号：EP16774366.5

申请日：2016-04-01

申请人： NantBioScience, Inc. , Nantomics, LLC , Nant Holdings IP, LLC

发明人： RABIZADEH, Shahrooz , KAYVAN, Niazi , BUZKO, Sasha , WEINGARTEN, Paul , MCFARLANE, Heather , JUNCKER-JENSEN, Anna , GOLOVATO, Justin , SOON-SHIONG, Patrick , TAO, Chunlin , HO, David

IPC分类号： C07D417/12 , C07D417/14 , A61K31/427 , A61K31/4725 , A61P35/00

摘要： Compounds and compositions are presented that inhibit K-ras, and especially mutant K-ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.