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18 条记录 (耗时 0.014 秒)

    Cell isolation instrument
    2.
    发明公开
    Cell isolation instrument 有权
    Zellisolationsinstrument

    公开(公告)号：EP2551340A1

    公开(公告)日：2013-01-30

    申请号：EP12177415.2

    申请日：2012-07-23

    申请人： Nihon Kohden Corporation ,  TOKYO WOMEN'S MEDICAL UNIVERSITY

    发明人： Shioyama, Takahiro ,  Suzuki, Akane ,  Okano, Teruo ,  Shimizu, Tatsuya ,  Haraguchi, Yuji

    IPC分类号： C12M3/08

    CPC分类号： C12M45/02

    摘要： A cell isolation instrument (1) includes: a first container (20) which has an opening in an upper portion; a filtration member (22) which defines at least a part of a lower portion of the first container (20); an isolation member (10) which is movably housed in the first container to collide with a tissue, thereby isolating cells; and a second container (30) which houses the first container in a manner that the first container can be taken out.

    摘要翻译： 电池隔离器（1）包括：第一容器（20），其在上部具有开口; 限定第一容器（20）的下部的至少一部分的过滤构件（22）; 隔离构件（10），其可移动地容纳在第一容器中以与组织碰撞，从而隔离单元; 以及以能够取出第一容器的方式容纳第一容器的第二容器（30）。

    APPARATUS AND METHOD FOR DIAGNOSING TUMOR
    6.
    发明公开
    APPARATUS AND METHOD FOR DIAGNOSING TUMOR 审中-公开
    用于诊断肿瘤的装置和方法

    公开(公告)号：EP3239694A1

    公开(公告)日：2017-11-01

    申请号：EP17167028.4

    申请日：2017-04-19

    申请人： Nihon Kohden Corporation

    发明人： Shioyama, Takahiro ,  Suzuki, Akane ,  Amano, Yoshitaka

    IPC分类号： G01N21/64 ,  G01N15/14

    CPC分类号： C12Q1/6886 ,  G01N15/1429 ,  G01N15/1459 ,  G01N21/6428 ,  G01N21/6486 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2015/1488 ,  G01N2021/6439

    摘要： An apparatus and a method for diagnosing a tumor are provided. A histogram generating section (14) generates a histogram from a result of a measurement of fluorescence intensity of a suspension produced from a target sample. The histogram indicates a relation between the fluorescence intensity and the number of cells. A determination section (15) detects an S phase fluorescence intensity range corresponding to S phase cells based on the fluorescence intensity corresponding to a peak of the number of cells in the histogram, detects an abnormal fluorescence intensity range corresponding to tumor cells, based on a change in the number of cells in the S phase fluorescence intensity range, and performs a diagnosis of a tumor in the target sample based on an index of the number of cells in a range defined by excluding the abnormal fluorescence intensity range from the S phase fluorescence intensity range.

    摘要翻译： 提供了一种诊断肿瘤的装置和方法。 直方图生成部分（14）根据由目标样本产生的悬浮液的荧光强度的测量结果生成直方图。 直方图表示荧光强度和细胞数量之间的关系。 判定部（15）基于与直方图中的细胞数的峰值对应的荧光强度，检测与S相细胞对应的S相荧光强度范围，根据该判定结果，检测与肿瘤细胞对应的异常荧光强度范围 改变S期荧光强度范围内的细胞数，并基于通过从S期荧光排除异常荧光强度范围而限定的范围内的细胞数目指标来执行目标样本中肿瘤的诊断 强度范围。

    Cell analyzing apparatus and cell analyzing method
    7.
    发明公开
    Cell analyzing apparatus and cell analyzing method 审中-公开
    Zellanalysevorrichtung und Zellanalyseverfahren

    公开(公告)号：EP2857828A1

    公开(公告)日：2015-04-08

    申请号：EP14185334.1

    申请日：2014-09-18

    申请人： Nihon Kohden Corporation

    发明人： Takeda, Sunao ,  Kubo, Hirotsugu ,  Shioyama, Takahiro ,  Suzuki, Akane ,  Nomura, Kenichi ,  Kato, Yo ,  Hinata, Nae

    IPC分类号： G01N21/64 ,  G01N15/14 ,  A61B5/00

    CPC分类号： G06K9/00127 ,  A61B5/0071 ,  G01N15/1429 ,  G01N15/1459 ,  G01N21/6428 ,  G01N2015/1006 ,  G01N2015/1402 ,  G01N2015/1486 ,  G01N2015/1488 ,  G01N2021/6439

    摘要： A cell analyzing apparatus (1) includes: a first histogram acquiring section (11) which is configured to acquire a first histogram of fluorescence intensities by using a result of a measurement of a number of nuclear stained cells; a second histogram acquiring section (12) which is configured to acquire a second histogram that is normalized based on a fluorescence intensity value indicating a maximum value of the first histogram; a determining section (14) which is configured to determine whether cancer cells exist or not, based on one of the first histogram and the second histogram; and an outputting section (15) which is configured to output a result of the determination performed by the determining section.

    摘要翻译： 细胞分析装置（1）包括：第一直方图获取部（11），其被配置为通过使用核染色细胞的数量的测量结果来获取荧光强度的第一直方图; 第二直方图获取部（12），其被配置为获取基于指示所述第一直方图的最大值的荧光强度值被归一化的第二直方图; 基于所述第一直方图和所述第二直方图之一，被配置为确定是否存在癌细胞的确定部分（14）; 以及输出部（15），其被配置为输出由所述确定部执行的所述确定的结果。

    Method and apparatus for analyzing cells
    8.
    发明公开
    Method and apparatus for analyzing cells 有权
    Verfahren und Vorrichtung zur分析von Zellen

    公开(公告)号：EP2690439A1

    公开(公告)日：2014-01-29

    申请号：EP13177448.1

    申请日：2013-07-22

    申请人： Nihon Kohden Corporation

    发明人： Shioyama, Takahiro ,  Suzuki Akane ,  Kubo, Hirotsugu ,  Takeda, Sunao

    IPC分类号： G01N33/574 ,  G01N21/64

    CPC分类号： G01N33/5091 ,  G01N15/1429 ,  G01N21/6428 ,  G01N33/574 ,  G01N33/57496

    摘要： A method of analyzing cells, the method comprising: measuring a number of cells which are nuclear stained, in a to-be-determined tissue, and acquiring a histogram showing a fluorescence intensity based on a result of the measurement; analyzing the histogram, and acquiring data of predetermined parameters; comparing the data of the parameters with first thresholds predetermined for the parameters, to perform a first cancer determination for each of the parameters on the to-be-determined tissue; performing a scoring process for each of the parameters, on a result of the first cancer determination for each of the parameters, to calculate scores of the parameters; and combining the scores of the parameters with one another, thereby performing a second cancer determination on the to-be-determined tissue.

    摘要翻译： 一种分析细胞的方法，所述方法包括：在待确定的组织中测量被核染色的细胞数量，并且基于测量结果获取显示荧光强度的直方图; 分析直方图，并获取预定参数的数据; 将参数的数据与为参数预定的第一阈值进行比较，以对待确定的组织上的每个参数执行第一次癌症确定; 根据每个参数的第一次癌症确定的结果对每个参数进行评分过程，以计算参数的分数; 并且将参数的得分相互组合，从而对待确定的组织进行第二次癌症测定。