公开(公告)号：EP2088460A1

公开(公告)日：2009-08-12

申请号：EP07828084.9

申请日：2007-11-27

申请人： Nikon Corporation

发明人： MAIYA, Nobuhiko

IPC分类号： G02B21/36 ,  G01N21/64 ,  G06T1/00

CPC分类号： G02B21/367

摘要： It is a proposition of the present invention to provide an image processing apparatus and an image processing program which can reduce a user's burden when performing tracking observation of a specimen. In addition, it is also a proposition of the present invention to provide a user friendly observing system. Therefore, an image processing apparatus of the present invention includes a storage unit which takes in a plurality of slice images acquired from a specific area of a specimen by each of Z-stack shootings performed at different time point, associates the plurality of slice images each with a shooting time point and a slice height z of the shooting time point, and stores the plurality of slice images as one of slice image groups, a manual selecting unit which allows a user to manually select a slice image from one of slice image groups stored by the storage unit as a representing slice images (Ia, Ib, Ic, ...) of said one of slice image groups, and an automatic selecting unit which automatically selects a slice image from another one of slice image groups stored by the storage unit, as a representing slice image of said another one of slice image groups, based on a selecting standard information indicating a result of the manual selection.

摘要翻译： 本发明的目的在于提供一种图像处理装置和图像处理程序，该图像处理装置和图像处理程序能够在进行跟踪观察时减少用户的负担。 此外，本发明的另一个目的是提供一种用户友好的观察系统。 因此，本发明的图像处理装置包括存储单元，其通过在不同时间点执行的每个Z堆叠拍摄获取从样本的特定区域获取的多个切片图像，将多个切片图像各自相关联 具有拍摄时间点的拍摄时间点和切片高度z，并且将多个切片图像存储为切片图像组之一，手动选择单元，其允许用户从切片图像组之一手动选择切片图像 由所述存储单元存储为所述切片图像组中的所述一个图像组的代表切片图像（Ia，Ib，Ic，...），以及自动选择单元，其从另一个切片图像组中存储的切片图像组中自动选择切片图像 存储单元，作为所述另一个切片图像组的代表切片图像，基于指示手动选择的结果的选择标准信息。

公开(公告)号：EP2034349B1

公开(公告)日：2017-10-25

申请号：EP07767085.9

申请日：2007-06-08

申请人： Nikon Corporation

发明人： MAIYA, Nobuhiko

IPC分类号： G02B21/36 ,  G02B21/16 ,  C12M1/00 ,  C12M1/34 ,  G02B21/00

CPC分类号： G02B21/367 ,  C12M41/14 ,  C12M41/46 ,  G02B21/0088 ,  G02B21/16

摘要： An observing apparatus includes: a photographic unit that takes a region where cells are present as an observation object region based upon a macro image captured at low magnification of an interior of a cell culture vessel, and photographs the cells in the observation object region; an illuminating unit that irradiates light upon the cells only during photography by the photographic unit; and an output unit that outputs a fluorescent image photographed by the photographic unit while irradiating light only during photography by the illuminating unit.

公开(公告)号：EP2088460B1

公开(公告)日：2017-10-25

申请号：EP07828084.9

申请日：2007-11-27

申请人： Nikon Corporation

发明人： MAIYA, Nobuhiko

IPC分类号： G02B21/36 ,  G01N21/64 ,  G06T1/00

CPC分类号： G02B21/367

摘要： It is a proposition of the present invention to provide an image processing apparatus and an image processing program which can reduce a user's burden when performing tracking observation of a specimen. In addition, it is also a proposition of the present invention to provide a user friendly observing system. Therefore, an image processing apparatus of the present invention includes a storage unit which takes in a plurality of slice images acquired from a specific area of a specimen by each of Z-stack shootings performed at different time point, associates the plurality of slice images each with a shooting time point and a slice height z of the shooting time point, and stores the plurality of slice images as one of slice image groups, a manual selecting unit which allows a user to manually select a slice image from one of slice image groups stored by the storage unit as a representing slice images (Ia, Ib, Ic, ...) of said one of slice image groups, and an automatic selecting unit which automatically selects a slice image from another one of slice image groups stored by the storage unit, as a representing slice image of said another one of slice image groups, based on a selecting standard information indicating a result of the manual selection.

公开(公告)号：EP3239287A1

公开(公告)日：2017-11-01

申请号：EP14909103.5

申请日：2014-12-26

申请人： The University of Tokyo ,  Nikon Corporation

发明人： MURATA, Masayuki ,  KANO, Fumi ,  NOGUCHI, Yoshiyuki ,  MAIYA, Nobuhiko ,  IWAMOTO, Chisako ,  YAMASAKI, Shoko ,  YAMASHITA, Masafumi

IPC分类号： C12M1/34 ,  G01N21/27 ,  G01N33/48 ,  G01N33/483 ,  G06T7/20

CPC分类号： G01N15/1475 ,  C12M1/34 ,  G01N21/27 ,  G01N33/48 ,  G01N33/483 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1497 ,  G06T7/0012 ,  G06T7/20 ,  G06T2207/10056 ,  G06T2207/30024

摘要： An analysis device includes an acquisition unit configured to acquire an image of a cell and an identification unit configured to identify elements that are identifiable on the basis of the image of cell acquired by the acquisition unit. Characteristic quantities of the elements identified by the identification unit are calculated, a correlation between the characteristic quantities is calculated on the basis of the calculated characteristic quantities of the elements, and a correlation between the elements is calculated on the basis of the calculated correlation between the characteristic quantities.

摘要翻译： 分析装置包括：获取单元，被配置为获取单元的图像;以及识别单元，被配置为基于由获取单元获取的单元的图像来识别可识别的元素。 计算由识别单元识别的元素的特征量，基于计算出的元素的特征量计算特征量之间的相关性，并且基于计算出的元素之间的相关性计算元素之间的相关性 特征量。

公开(公告)号：EP2085806A1

公开(公告)日：2009-08-05

申请号：EP07828091.4

申请日：2007-11-29

申请人： Nikon Corporation

发明人： MAIYA, Nobuhiko

IPC分类号： G02B21/36 ,  G02B21/16 ,  H04N5/225 ,  H04N5/915

CPC分类号： H04N5/915 ,  G02B21/367 ,  G11B27/034 ,  G11B27/34 ,  H04N1/2104 ,  H04N1/2133 ,  H04N21/4334

摘要： Provided with a time-lapse imaging unit which repeatedly captures a specimen at predetermined time intervals and generates a plurality of images, and a recording unit which records either an image group including one or more of the images captured during a predetermined period among a period of a time-lapse capturing performed by the time-lapse imaging unit or an image group including one or more of the images picked at predetermined time intervals among the period of the time-lapse capturing performed by the time-lapse imaging unit. Alternatively, addition to the above-described recording unit, provided with a recording unit which clips an image of a predetermined area from each of the plurality of images generated by the time-lapse imaging unit, and records an image group including one or more images clipped, Thus, data generated in time-lapse photography are managed favorably in a microscope apparatus provided with a time-lapse imaging unit which repeatedly captures a specimen at predetermined time intervals and generates a plurality of images.

摘要翻译： 具有以规定的时间间隔反复拍摄样本并产生多个图像的延时成像单元，以及记录单元，其记录包含在规定期间内拍摄的图像中的一个或多个的图像组， 延时成像单元执行的延时捕获或包括在由延时成像单元执行的延时捕获的周期中以预定时间间隔拾取的一个或多个图像的图像组。 或者，除了上述记录单元之外，设置有记录单元，该记录单元从由延时成像单元生成的多个图像中的每一个图像中剪切预定区域的图像，并记录包括一个或多个图像的图像组 因此，在具有延时成像单元的显微镜装置中，以预定的时间间隔重复拍摄样本并生成多个图像，有利地管理在延时拍摄中产生的数据。

公开(公告)号：EP2034349A1

公开(公告)日：2009-03-11

申请号：EP07767085.9

申请日：2007-06-08

申请人： Nikon Corporation

发明人： MAIYA, Nobuhiko

IPC分类号： G02B21/36

CPC分类号： G02B21/367 ,  C12M41/14 ,  C12M41/46 ,  G02B21/0088 ,  G02B21/16

摘要： An observing apparatus includes: a photographic unit that takes a region where cells are present as an observation object region based upon a macro image captured at low magnification of an interior of a cell culture vessel, and photographs the cells in the observation object region; an illuminating unit that irradiates light upon the cells only during photography by the photographic unit; and an output unit that outputs a fluorescent image photographed by the photographic unit while irradiating light only during photography by the illuminating unit.

摘要翻译： 观察装置包括：摄影单元，其以细胞存储的区域为基础，以细胞培养容器内部的低倍率拍摄的宏观图像作为观察对象区域，并对观察对象区域中的细胞进行拍摄; 照明单元，其仅在照相单元拍摄期间将光照射到单元上; 以及输出单元，其输出由照相单元拍摄的荧光图像，同时仅在照明单元拍摄期间照射光。