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    METHOD FOR PRODUCING A PIPERIDIN-4-ONE-DERIVATIVE
    2.
    发明授权
    METHOD FOR PRODUCING A PIPERIDIN-4-ONE-DERIVATIVE 有权
    用于生产哌啶-4-衍生

    公开(公告)号：EP2058303B1

    公开(公告)日：2010-08-18

    申请号：EP07829479.0

    申请日：2007-10-10

    申请人： Nippon Soda Co., Ltd.

    发明人： OOOKA, Hirohito ,  SHIBATA, Yasushi ,  INOUE, Hiroki ,  IMAGAWA, Tsutomu

    IPC分类号： C07D221/22 ,  C07D491/113

    CPC分类号： C07D221/22 ,  C07D221/24 ,  C07D491/113

    摘要： Disclosed is a method for producing a piperidin-4-one derivative which is useful as an intermediate for agricultural chemicals or pharmaceutical products. Specifically, a piperidin-4-one derivative represented by the formula (III-a) or (III-b) below is produced by reacting a cyclic bis(aminol) ether compound represented by the formula (I) below and an acetone derivative represented by the formula (II) below in the presence of at least one substance selected from the group consisting of protonic acids, Lewis acids, acid halides and dialkyl sulfuric acids.

    METHOD FOR PRODUCING PIPERIDIN-4-ONE-DERIVATIVE
    3.
    发明公开
    METHOD FOR PRODUCING PIPERIDIN-4-ONE-DERIVATIVE 有权
    VERFAHREN ZUR HERSTELLUNG EINES PIPERIDIN-4-ON-DERIVATS

    公开(公告)号：EP2058303A1

    公开(公告)日：2009-05-13

    申请号：EP07829479.0

    申请日：2007-10-10

    申请人： Nippon Soda Co., Ltd.

    发明人： OOOKA, Hirohito ,  SHIBATA, Yasushi ,  INOUE, Hiroki ,  IMAGAWA, Tsutomu

    IPC分类号： C07D221/22 ,  C07D491/113

    CPC分类号： C07D221/22 ,  C07D221/24 ,  C07D491/113

    摘要： Provided is a method for producing a piperidin-4-one derivative useful as an intermediate for agricultural chemicals or pharmaceutical products. A piperidin-4-one derivative represented by formula (III-a) or formula (III-b) is produced by reacting a cyclic bis(aminol)ether compound represented by formula (I) and an acetone derivative represented by formula (II) in the presence of at least one substance selected from the group consisting of protonic acids, Lewis acids, acid halides and dialkyl sulfuric acids.

    摘要翻译： 提供可用作农药或药品的中间体的哌啶-4-酮衍生物的制造方法。 由式（I-a）或式（III-b）表示的哌啶-4-酮衍生物由式（I）表示的环状双（氨基醇）醚化合物与由式（II）表示的丙酮衍生物反应制备， 在至少一种选自质子酸，路易斯酸，酰卤和二烷基硫酸的物质存在下进行。

    PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND
    5.
    发明公开
    PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND 有权
    制造方法的有机锂和方法用于制备取代的芳族连接

    公开(公告)号：EP2371831A1

    公开(公告)日：2011-10-05

    申请号：EP09834520.0

    申请日：2009-12-25

    申请人： Nippon Soda Co., Ltd.

    发明人： INOUE, Hiroki

    IPC分类号： C07F1/02 ,  C07C211/14 ,  C07C217/08 ,  C07F5/02

    CPC分类号： C07C217/08 ,  C07C211/14 ,  C07F1/02 ,  C07F5/025

    摘要： A method for producing an organolithium compound includes the step of reacting an aromatic compound or a halogenated unsaturated aliphatic compound and a lithiating agent in the presence of a coordinating compound containing three or more elements having a coordinating ability in a molecule, at least one thereof being a nitrogen element, or a coordinating compound containing three or more oxygen elements having a coordinating ability in a molecule, at least one of the groups containing the oxygen elements having a coordinating ability being a tertiary alkoxy group, at a temperature of -40°C to 40°C.

    摘要翻译： 一种在有机锂化合物的制造方法包括使芳族化合物或卤代不饱和脂肪族化合物和配位化合物的存在下，锂化剂含有在分子中具有一个配位能力，其至少一个为三个或更多个元件的步骤 氮元素，或含有在分子中具有一个配位能力，含有具有配位能力是叔烷氧基中的氧元素，在-40℃的温度下的基团中的至少一个三个或更多个氧元素的配位化合物 至40℃